Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Junzo Saegusa"'
Autor:
Shigeru Kyuwa, Junzo Saegusa, Fumihiro Taguchi, Yoichiroh Iwakura, Yasuhiro Yoshikawa, Shutoku Matsuyama, Satoshi Takagaki, Yoh-ichi Tagawa
Publikováno v:
Viral Immunology. 23:437-442
Previously, we showed that intraperitoneal infection with murine coronavirus strain JHM (JHMV) established a persistent infection with subacute granulomatous serositis in interferon-gamma-deficient C57BL/6 (B6-GKO) mice. Herein, we characterize a var
Publikováno v:
Experimental Animals. 56:393-397
To assess delayed fertility in male growth-retarded (grt) mice with congenital primary hypothyroidism, their testes were chronologically examined. The testicular weight in grt mice was significantly lower than age-matched normal mice until 8 weeks bu
Publikováno v:
Experimental and Molecular Pathology. 79:68-73
We investigated the kinetics of decorin, biglycan and thrombospondin-1 in mercuric chloride-treated Brown Norway (BN) rats. BN rats were injected subcutaneously with 1 mg/kg b.w. of mercuric chloride one or three times. The kidney was examined histop
Publikováno v:
INDUSTRIAL HEALTH. 42:219-225
Reproductive toxicity of 2-bromopropane (2BP), a substitute for ozone layer-depleting chloro-fluorocarbon, was found among the workers in an electronics factory in Korea in 1995. Furthermore the importance of testicular toxicity has been realized sin
Publikováno v:
Autoimmunity. 36:247-254
Subpopulations of infiltrating lymphocytes, professional antigen-presenting cells (APCs), and Th1/Th2 cytokines that could initiate an autoimmune sialodacryoadenitis were studied in the IQI/Jic mouse model of primary Sjögren's syndrome. Although lym
Publikováno v:
Experimental and Toxicologic Pathology. 52:235-240
IQI/Jic (IQI) mice are an ICR-derived inbred strain developed in Japan, and it is known that aged females of this strain develop allergic dermatitis of spontaneous nature. In the present study, young IQI female mice which were sensitized with picryl
Publikováno v:
Experimental Animals. 46:103-109
IQI/Jic mice showed a high incidence of subcapsular spindle cell hyperplasia (SCH) in the adrenal cortex accompanied by prominent mast cell infiltration. SCH-positive animals appeared as early as at 3 months of age, with an incidence of 18% in males
Autor:
Hisayo Kubota, Junzo Saegusa
Publikováno v:
Journal of Veterinary Medical Science. 59:897-903
Focal infiltration of lymphocytes with parenchymal destruction was noted in both salivary and lacrimal glands of IQI/Jic mice. The sialadenitis was found in more than 80% of female mice at all ages examined. The lesion progressed after 6 months and b
Publikováno v:
Experimental Animals. 45:353-360
The thymus of IQI/Jic mice aged 3 to 15 months was studied chronologically by flow cytometry and immunohistochemistry. Thymic B cells (Thy B) expressing the surface marker B220+IgM+ were detected in both sexes, but were more prominent in females. Thy
Publikováno v:
Experimental Animals. 41:239-242
Numerous plasma cells and B cells were present in the thymuses of aged WHT/Ht mice. Plasma cells containing IgG and the follicle-like structure were present in the cortex and medulla, respectively. In these respects, WHT/Ht strain of mice is unique a