Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Junzo Hirono"'
Autor:
Takahiro Ishikawa, Ichiro Takashima, Toshio Iijima, Riichi Kajiwara, Takaaki Sato, Akira Shimizu, Junzo Hirono, Hiroshi Hamana
Publikováno v:
Anatomical Science International. 83:195-206
Since the discovery of the superfamily of approximately 1000 odorant receptor genes in rodents, the structural simplicity as well as the complexity of the olfactory system have been revealed. The simple aspects include the one neuron-one receptor rul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc2c3e0585d3544aa44b3ad8d3468c3
https://doi.org/10.1111/j.1447-073x.2007.00215.x
https://doi.org/10.1111/j.1447-073x.2007.00215.x
Autor:
Makoto Emura, Hiroshi Hamana, Akio Tsuboi, Takaaki Sato, Miwako Kizumi, Junzo Hirono, Shigeyoshi Itohara, Ko Kobayakawa, Reiko Kobayakawa
Publikováno v:
Scientific Reports
Enantiomeric pairs of mirror-image molecular structures are difficult to resolve by instrumental analyses. The human olfactory system, however, discriminates (−)-wine lactone from its (+)-form rapidly within seconds. To gain insight into receptor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a722c524ec77078079aefeb23133daa
http://europepmc.org/articles/PMC4566093
http://europepmc.org/articles/PMC4566093
Publikováno v:
Journal of General Physiology. 122:255-264
It has long been believed that vertebrate olfactory signal transduction is mediated by independent multiple pathways (using cAMP and InsP3 as second messengers). However, the dual presence of parallel pathways in the olfactory receptor cell is still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fd143c531eb68045d8a4d397b656cce
https://doi.org/10.1085/jgp.200308867
https://doi.org/10.1085/jgp.200308867
Publikováno v:
Chemical Senses. 28:87-104
In order to comprehend the strategy of odor encoding by odorant receptors, we isolated 2740 mouse receptor neurons from four olfactory epithelial zones and classified them in terms of their sensitivities and tuning specificities to a chiral pair of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1541b82e04b7324ea30f916fd71728
https://doi.org/10.1093/chemse/28.2.87
https://doi.org/10.1093/chemse/28.2.87
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
The discriminatory capacity of the mammalian olfactory system is such that thousands of volatile chemicals are perceived as having distinct odors. Here we used a combination of calcium imaging and single-cell RT–PCR to identify odorant receptors (O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4ed52bbbc0fdbec6bb6dd1d04c2563
https://doi.org/10.1016/s0092-8674(00)80581-4
https://doi.org/10.1016/s0092-8674(00)80581-4
Publikováno v:
Scopus-Elsevier
1. Odor responses to two homologous series of n-fatty acids (nFA) and n-aliphatic alcohols (nAA) with a straight chain of three to nine carbons were examined by measuring odor-induced [Ca2+]i increase in mouse olfactory receptor neurons (ORNs) isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71ae229faa9f58a618ad5f50e7d1e07
https://doi.org/10.1152/jn.1994.72.6.2980
https://doi.org/10.1152/jn.1994.72.6.2980
Publikováno v:
Journal of Neuroscience Methods. 42:185-194
A new method is described for isolating olfactory receptor neurons suitable for simultaneous recording of odorant responses in several cells. This method, called "tissue printing" by Cassab and Varner, was used to isolate cells for measurement of odo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e3fc0f40b078f28a95a670c5248864
https://doi.org/10.1016/0165-0270(92)90098-x
https://doi.org/10.1016/0165-0270(92)90098-x
Publikováno v:
Journal of neuroscience methods. 185(2)
Heterologous functional expression system for odorant receptors (ORs) is essential for investigating the structure-activity relationship (SAR) of various ligands. Different systems that coexpressed ORs with different G-protein alpha subunits (Galpha)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38a20fed7bf6ef1a5fc101a3ba6925d7
https://pubmed.ncbi.nlm.nih.gov/19799933
https://pubmed.ncbi.nlm.nih.gov/19799933
Publikováno v:
Chemical senses. 34(2)
The discrimination of thousands of odorants is mediated by several hundred olfactory receptors (ORs). It is generally accepted that the main strategy in encoding odor quality is a combinatorial receptor code scheme, in which odorants are discriminate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fa5eaaa27569364812b947252ee025
https://pubmed.ncbi.nlm.nih.gov/19073951
https://pubmed.ncbi.nlm.nih.gov/19073951
Publikováno v:
Neuroscience letters. 174(2)
The local distribution of odor responsivity was studied in isolated mouse olfactory neurons retaining their original spatial relationships in intact tissue. The selectivity for three odorants and population of responsive cells were estimated from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e65a467aa57838bf64c597a27cd50ca
https://pubmed.ncbi.nlm.nih.gov/7970179
https://pubmed.ncbi.nlm.nih.gov/7970179