Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Junzhi Ji"'
Autor:
Yiwan Song, Zhongmao Yuan, Junzhi Ji, Yang Ruan, Xiaowen Li, Lianxiang Wang, Weijun Zeng, Keke Wu, Wenshuo Hu, Lin Yi, Hongxing Ding, Mingqiu Zhao, Shuangqi Fan, Zhaoyao Li, Jinding Chen
Publikováno v:
Vaccines, Vol 12, Iss 8, p 948 (2024)
The occurrence of classical swine fever (CSF) poses a significant threat to the global swine industry. Developing an effective and safe vaccine is crucial for preventing and controlling CSF. Here, we constructed self-assembled ferritin nanoparticles
Externí odkaz:
https://doaj.org/article/c65a4252b182440a856e2c342eb3a4a2
Publikováno v:
ASSAY and Drug Development Technologies. 12:352-360
Human stem cell-derived cardiomyocytes provide a cellular model for the study of electrophysiology in the human heart and are finding a niche in the field of safety pharmacology for predicting proarrhythmia. The cardiac L-type Ca2+ channel is an impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763b2bc4d2cd4e37c311bb85956a95d7
https://doi.org/10.1089/adt.2014.596
https://doi.org/10.1089/adt.2014.596
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 341:510-517
Human stem cell-derived cardiomyocytes provide new models for studying the ion channel pharmacology of human cardiac cells for both drug discovery and safety pharmacology purposes. However, detailed pharmacological characterization of ion channels in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cde526b606c59d6c0a676821c9dceea
https://doi.org/10.1124/jpet.112.192609
https://doi.org/10.1124/jpet.112.192609
Autor:
Xiaoyou Ying, Harry Meng, Junzhi Ji, James Cao, Jiesheng Kang, William F. Reynolds, David Rampe
Publikováno v:
Toxicology Letters. 208:62-68
Mephedrone (4-methylmethcathinone) is a new and popular drug of abuse widely available on the Internet and still legal in some parts of the world. Clinical reports are now emerging suggesting that the drug displays sympathomimetic toxicity on the car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb573877cd9817015305927833156c1e
https://doi.org/10.1016/j.toxlet.2011.10.010
https://doi.org/10.1016/j.toxlet.2011.10.010
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 334:619-626
Epigallocatechin-3-gallate (EGCG) is the major catechin found in green tea. EGCG is also available for consumption in the form of concentrated over-the-counter nutritional supplements. This compound is currently undergoing clinical trials for the tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e60effcc8aed313a6ff79b4d485a18f5
https://doi.org/10.1124/jpet.110.169391
https://doi.org/10.1124/jpet.110.169391
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 36:1104-1109
Summary 1. The non-selective K(+) channel blocker 4-aminopyridine (4-AP) has shown clinical efficacy in the treatment of neurological disorders such as multiple sclerosis. The clinical usefulness of 4-AP is hampered by its ability to produce seizures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f92c1eb11526dd61d666311cba86cc
https://doi.org/10.1111/j.1440-1681.2009.05200.x
https://doi.org/10.1111/j.1440-1681.2009.05200.x
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 82:1006-1017
We hypothesized that regional differences in electrophysiological properties exist within the musculature of the feline lower esophageal sphincter (LES) and that they may potentially contribute to functional asymmetry within the LES. Freshly isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fc0041e820d4f0bf72281cd22a2751
https://doi.org/10.1139/y04-090
https://doi.org/10.1139/y04-090
Publikováno v:
Neurogastroenterology and Motility. 16:325-334
Muscle from the proximal smooth muscle (SM) oesophagus of the cat demonstrates contractions of greater amplitude and greater sensitivity to cholinergic stimulation than muscle from the distal SM oesophagus. In the light of the central role of calcium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22cd00d62d0584afa5f1bc7cab3cacd
https://doi.org/10.1111/j.1365-2982.2004.00523.x
https://doi.org/10.1111/j.1365-2982.2004.00523.x
Autor:
Laura Sheu, Xiaodong Gao, Junzhi Ji, Herbert Y. Gaisano, Frederique Varoqueaux, Nils Brose, Xiaohang Huang, Eva A. Pasyk
Publikováno v:
Journal of Biological Chemistry. 278:27556-27563
The slower kinetics of insulin release from pancreatic islet beta cells, as compared with other regulated secretory processes such as chromaffin granule secretion, can in part be explained by the small number of the insulin granules that are docked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e3f95e121e8a3028f32f365025a469
https://doi.org/10.1074/jbc.m303203200
https://doi.org/10.1074/jbc.m303203200
Publikováno v:
Biochemical and Biophysical Research Communications. 306:298-302
We recently reported that non-secretory gastrointestinal smooth muscle cells also possessed SNARE proteins, of which SNAP-25 regulated Ca(2+)-activated (K(Ca)) and delayed rectifier K(+) channels (K(V)). Voltage-gated, long lasting (L-type) calcium c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277b64557acf9e6c316ad4b399430f50
https://doi.org/10.1016/s0006-291x(03)00968-9
https://doi.org/10.1016/s0006-291x(03)00968-9