Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Junzhen Tan"'
1
Akademický článek
Toxicity studies of condensed fuzheng extract in mice and rats
Autor: JiDa Wang, Li Wang, Junzhen Tan, RunDong Chai, Ying Wang, Yue Wang, ShuWu Zhao, XiangLing Wang, YuHong Bian, JianWei Liu
Publikováno v: Heliyon, Vol 10, Iss 3, Pp e24780- (2024)
Nutritional supplements have been used to improve immune function. Condensed fuzheng extract (CFE) is a well-known traditional Chinese medicine (TCM) formula that is predominantly made from sheep placenta, Astragalus mongholicus Bunge, and Polygonatu
Externí odkaz: https://doaj.org/article/a10c1bbffb344be0a79b07c9f72d08f4
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2
Akademický článek
PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism
Autor: Mingming Sun, Leilei Li, Yujia Niu, Yingzhi Wang, Qi Yan, Fei Xie, Yaya Qiao, Jiaqi Song, Huanran Sun, Zhen Li, Sizhen Lai, Hongkai Chang, Han Zhang, Jiyan Wang, Chenxin Yang, Huifang Zhao, Junzhen Tan, Yanping Li, Shuangping Liu, Bin Lu, Min Liu, Guangyao Kong, Yujun Zhao, Chunze Zhang, Shu-Hai Lin, Cheng Luo, Shuai Zhang, Changliang Shan
Publikováno v: Acta Pharmaceutica Sinica B, Vol 13, Iss 1, Pp 157-173 (2023)
Metabolic reprogramming is a hallmark of cancer, including lung cancer. However, the exact underlying mechanism and therapeutic potential are largely unknown. Here we report that protein arginine methyltransferase 6 (PRMT6) is highly expressed in lun
Externí odkaz: https://doaj.org/article/36c8e8bd351c4e309e5b7c65ea0fc457
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3
Akademický článek
PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1
Autor: Fei Xie, Han Zhang, Kongkai Zhu, Cheng‐Shi Jiang, Xiaoya Zhang, Hongkai Chang, Yaya Qiao, Mingming Sun, Jiyan Wang, Mukuo Wang, Junzhen Tan, Tao Wang, Lianmei Zhao, Yuan Zhang, Jianping Lin, Chunze Zhang, Shuangping Liu, Jianguo Zhao, Cheng Luo, Shuai Zhang, Changliang Shan
Publikováno v: MedComm, Vol 4, Iss 2, Pp n/a-n/a (2023)
Abstract Protein arginine methyltransferase 5 (PRMT5) is a major type II enzyme responsible for symmetric dimethylation of arginine (SDMA), and plays predominantly roles in human cancers, including in ovarian cancer. However, the exactly roles and un
Externí odkaz: https://doaj.org/article/8c1a0d509b124df5ae4a85577bce88bb
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4
Akademický článek
Neuroprotection of Triptolide against Amyloid-Beta1-42-induced toxicity via the Akt/mTOR/p70S6K-mediated Autophagy Pathway
Autor: PENGJUAN XU, ZIXUAN WU, YANFEI PENG, JING GAO, FANG ZHENG, JUNZHEN TAN, JING XU, TAO WANG
Publikováno v: Anais da Academia Brasileira de Ciências, Vol 94, Iss 2 (2022)
Abstract Triptolide is a natural active compound that has significant neuroprotective properties and shows promising effects in the treatment of Alzheimer’s disease (AD). Recent studies have shown that autophagy occurs in AD. In this study, we dete
Externí odkaz: https://doaj.org/article/bdd5a0759616450f8d644e2cf7848eee
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5
Nanosized copper particles induced mesangial cell toxicity via the autophagy pathway
Autor: Pengjuan Xu, Min Cao, Xueqian Dong, Zhichao Yu, Jianwei Liu, Junzhen Tan, Yiyi Wang, Tao Li, Shuwu Zhao
Publikováno v: Brazilian Journal of Medical and Biological Research, Volume: 55, Article number: e12252, Published: 11 NOV 2022
Brazilian Journal of Medical and Biological Research v.55 2022
Brazilian Journal of Medical and Biological Research
Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
Nanosized copper particles (nano Cu) have been incorporated into products in multiple industries, although studies have demonstrated that these particles are nephrotoxic. We investigated the cytotoxicity of nanosized copper particles on rat mesangial
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93f5c36c4553e337c7d92533f23ff94
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2022000100674&lng=en&tlng=en
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6
Neuroprotection of Triptolide against Amyloid-Beta1-42-induced toxicity via the Akt/mTOR/p70S6K-mediated Autophagy Pathway
Autor: PENGJUAN XU, ZIXUAN WU, YANFEI PENG, JING GAO, FANG ZHENG, JUNZHEN TAN, JING XU, TAO WANG
Publikováno v: Anais da Academia Brasileira de Ciências v.94 n.2 2022
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Anais da Academia Brasileira de Ciências, Volume: 94, Issue: 2, Article number: e20210938, Published: 08 AUG 2022
Triptolide is a natural active compound that has significant neuroprotective properties and shows promising effects in the treatment of Alzheimer’s disease (AD). Recent studies have shown that autophagy occurs in AD. In this study, we determined wh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53b5dedf58050bca2e4abccd67ab445
https://pubmed.ncbi.nlm.nih.gov/35946645
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7
PIKE-A promotes glioblastoma growth by driving PPP flux through increasing G6PD expression mediated by phosphorylation of STAT3
Autor: Hao Sheng, Qingrong Huang, Junzhen Tan, Yanping Li, Guo Chen, Tingfeng Wu, Huifang Zhao, Shuangping Liu, Changliang Shan, Jiyan Wang, Bei Lan, Jiaqi Song, Yingzhi Wang, Zhen Li, Yuan Zhang, Huanran Sun, Mingming Sun, Shuai Zhang
Publikováno v: Biochemical pharmacology. 192
Reprogramming of energy metabolism is a hallmarkofcancer, and the pentose phosphate pathway (PPP) is a major glucose metabolic pathway important for meeting the cellular demands of biosynthesis and anti-oxidant defense. Our previous study showed that
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16626ca69dbda13ec97687f18afc054
https://pubmed.ncbi.nlm.nih.gov/34411567
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8
Quercetin Inhibits Breast Cancer Stem Cells via Downregulation of Aldehyde Dehydrogenase 1A1 (ALDH1A1), Chemokine Receptor Type 4 (CXCR4), Mucin 1 (MUC1), and Epithelial Cell Adhesion Molecule (EpCAM)
Autor: Shen Li, Qingyan Liu, Zibo Zhao, Lihong Yang, Dongmei Ye, Laixiu Yang, Rong Wang, Xiuli Li, Junzhen Tan, Qing Cai
Publikováno v: Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
BACKGROUND Quercetin, nature's most common flavonoid, possesses anticarcinogenic properties against various forms of cancer. The aim of this study was to investigate the effect of quercetin on breast cancer stem cells in the MDA-MB-231 cell line, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9b309ce5fb61daa8693c7f361ed3b9
https://doi.org/10.12659/msm.908022
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9
Aortic wall proteomic analysis in spontaneously hypertensive rats with a blood pressure decrease induced by 6-week load-free swimming
Autor: Junzhen Tan, Haiying Li, Hong Feng, Y U Zhang, Wei Liu, Ning Jiang, Yungang Zhao, Wen Fang, Derong Zhang, Yong Zhang, Xiaoling Zhao
Publikováno v: Biomedical reports. 3(5)
Decreased arterial compliance is one of the earliest detectable manifestations of adverse structural and functional changes within the vessel wall in hypertension. The proteomic approach is a powerful technique to analyze a complex mixture of protein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cacaecd86a1b402d7ca3c1b3c3dbc2ef
https://pubmed.ncbi.nlm.nih.gov/26405545
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