Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Junzhao Yin"'
Autor:
Ting Zhang, Lingfeng You, Jianyan Xu, Junzhao Yin, Bolei Qu, Yuchang Mao, Beibei Fu, Dan Cao, Linda Zhao, Jun Feng, Min Hu, Feng He
Publikováno v:
Cancer Research. 83:LB031-LB031
Current clinical HER2-targeting ADCs, especially T-DXd, have shown strong efficacy in HER2-expressing/mutant cancers, however, with adverse events such as hematologic toxicities and interstitial lung disease (ILD)/pneumonitis. Here we presented a pot
Autor:
Aishen Gong, Jun Feng, Piaoyang Sun, Qiyue Hu, Lei Zhang, Xiaoyan Zhu, Wangyang Tu, Mimi Wan, Guoji Xu, Jijun Yuan, Junzhao Yin, Dan Wang, Bing Lin, Hongbo Fei, Hejun Lu, Qian Wang
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(11)
The MAPK pathway is identified as one of the most important pathways involved in cell proliferation and differentiation. A key kinase in the pathway, the Mitogen-activated protein kinase kinase (MEK) is recognized as a promising target for antitumor