Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Junying Qin"'
Autor:
Xiaolu Ma, Hui Fu, Chenyi Sun, Wei Wu, Wenya Hou, Zibin Zhou, Hui Zheng, Yifei Gong, Honglin Wu, Junying Qin, Huiqiang Lou, Jing Li, Tie-Shan Tang, Caixia Guo
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-11 (2024)
Abstract RAD18, an important ubiquitin E3 ligase, plays a dual role in translesion DNA synthesis (TLS) and homologous recombination (HR) repair. However, whether and how the regulatory mechanism of O-linked N-acetylglucosamine (O-GlcNAc) modification
Externí odkaz:
https://doaj.org/article/0a8abaa024654349b25fef0ef5747690
Autor:
Xiao-Qiong Chen, Xuan Zhang, Ding-Guo Pan, Guo-Yu Li, Rui-Xi Hu, Tao Wu, Tao Shen, Xin-Yi Cai, Xian-Shuo Cheng, Junying Qin, Fu-Hui Xiao, Yun-Feng Li
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33738- (2024)
Background: Colon adenocarcinoma (COAD) is one of the most common malignant tumors. The interplay involving ferroptosis between tumor and immune cells plays a crucial in cancer progression. However, the biological basis of this interplay in COAD deve
Externí odkaz:
https://doaj.org/article/e5714de55d374368a3e9e6d1f2670eb7
Publikováno v:
Nature metabolism. 3(1)
NADPH has long been recognized as a key cofactor for antioxidant defence and reductive biosynthesis. Here we report a metabolism-independent function of NADPH in modulating epigenetic status and transcription. We find that the reduction of cellular N
Autor:
Rong Liu, Qian Tao, Wenlin Chen, Yingying Wu, Ceshi Chen, Junying Qin, Yunxi Li, Fubing Li, Chuanyu Yang, Xinye Wang, Zhen Li, Hailin Zhang, Zhongmei Zhou
Publikováno v:
J Biol Chem
The Kruppel-like factor 5 (KLF5) transcription factor is highly expressed in basal type breast cancer and promotes breast cancer cell proliferation, survival, migration, and tumorigenesis. KLF5 protein stability is regulated by ubiquitination. In thi
Autor:
Tianning Zou, Wenlin Chen, Fei Ge, Hongyuan Li, Guosheng Ren, Zhongmei Zhou, Junying Qin, Rong Liu, Lin-Lin Liu, Ceshi Chen, Jing Tan
Publikováno v:
Oncotarget
The Kruppel-like factor 5 (KLF5) has been suggested to promote breast cell proliferation, survival and tumorigenesis. KLF5 protein degradation is increased by several E3 ubiquitin ligases, including WWP1 and SCFFbw7, through the ubiquitin-proteasome
Autor:
Yingying Wu1,2,3, Junying Qin1, Fubing Li1, Chuanyu Yang1, Zhen Li4, Zhongmei Zhou1, Hailin Zhang1, Yunxi Li4, Xinye Wang1, Rong Liu1, Qian Tao5, Wenlin Chen4 chenc@mail.kiz.ac.cn, Ceshi Chen1,6,7 chenwenlin@aliyun.com
Publikováno v:
Journal of Biological Chemistry. 11/22/2019, Vol. 294 Issue 47, p17837-17847. 11p.
Autor:
Hailin Zhang, Zhixiang Fan, Hou-Jun Xia, Ceshi Chen, Rong Liu, Dingyun You, Guang-Zhe Ge, Ming Shao, Chunyan Wang, Junying Qin, Wenlin Chen, Zhongmei Zhou
Publikováno v:
Nature Communications
The transcription factor KLF5 is highly expressed in basal-like breast cancer and promotes breast cancer cell proliferation, survival, migration and tumour growth. Here we show that, in breast cancer cells, KLF5 is stabilized by the deubiquitinase (D
Autor:
Li Shumo, Wenlin Chen, Jian Shen, Chunyan Wang, Rong Liu, Junying Qin, Fubing Li, Ceshi Chen, Chen Liang, Hailin Zhang, Ma Yun, Yingying Wu, Jing Wu, Zhongmei Zhou, Peiguo Shi, Zhi Nie
Publikováno v:
Oncotarget
// Chunyan Wang 1, 2, 3, * , Zhi Nie 3, * , Zhongmei Zhou 1 , Hailin Zhang 1 , Rong Liu 1 , Jing Wu 1, 2, 4 , Junying Qin 1, 2 , Yun Ma 3 , Liang Chen 3 , Shumo Li 3 , Wenlin Chen 5 , Fubing Li 1, 2 , Peiguo Shi 1, 2 , Yingying Wu 3 , Jian Shen 3 , C
Publikováno v:
Cancer Research. 75:4967-4967
The transcription factor KLF5 is highly expressed in basal triple-negative breast cancer (TNBC) and promotes breast cancer cell proliferation, survival and tumor growth. However, the mechanism by which KLF5 is regulated in breast cancer remains uncle