Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Junya Yamaguchi"'
Autor:
Junya Yamaguchi, Fumiharu Ohka, Masafumi Seki, Kazuya Motomura, Shoichi Deguchi, Yoshiki Shiba, Yuka Okumura, Yuji Kibe, Hiroki Shimizu, Sachi Maeda, Yuhei Takido, Ryo Yamamoto, Akihiro Nakamura, Kennosuke Karube, Ryuta Saito
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-7 (2024)
Abstract Mutations in the isocitrate dehydrogenase (IDH) gene are recognized as the key drivers in the oncogenesis of astrocytoma and oligodendroglioma. However, the significance of IDH mutation in tumor maintenance and malignant transformation has n
Externí odkaz:
https://doaj.org/article/f9f5ded7c6c5412cb0f008ce4aa78f77
Autor:
Yuji Kibe, Fumiharu Ohka, Kosuke Aoki, Junya Yamaguchi, Kazuya Motomura, Eiji Ito, Kazuhito Takeuchi, Yuichi Nagata, Satoshi Ito, Nobuhiko Mizutani, Yoshiki Shiba, Sachi Maeda, Tomohide Nishikawa, Hiroki Shimizu, Ryuta Saito
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Li-Fraumeni syndrome (LFS) is an autosomal dominant tumor predisposition syndrome caused by heterozygous germline mutations or deletions in the TP53 tumor suppressor gene. Central nervous system tumors, such as choroid plexus tumors, medullo
Externí odkaz:
https://doaj.org/article/8a4831412d03486798dd6a0ea60ec8dd
Autor:
Junya Yamaguchi, Fumiharu Ohka, Chalise Lushun, Kazuya Motomura, Kosuke Aoki, Kazuhito Takeuchi, Yuichi Nagata, Satoshi Ito, Nobuhiko Mizutani, Masasuke Ohno, Noriyuki Suzaki, Syuntaro Takasu, Yukio Seki, Takahisa Kano, Kenichi Wakabayashi, Hirofumi Oyama, Shingo Kurahashi, Kuniaki Tanahashi, Masaki Hirano, Hiroyuki Shimizu, Yotaro Kitano, Sachi Maeda, Shintaro Yamazaki, Toshihiko Wakabayashi, Yutaka Kondo, Atsushi Natsume, Ryuta Saito
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 7116-7126 (2023)
Abstract Background Rituximab, high‐dose methotrexate (HD‐MTX), procarbazine and vincristine (R‐MPV), has significantly prolonged the survival of patients with primary central nervous system lymphoma (PCNSL), but predictive factors for response
Externí odkaz:
https://doaj.org/article/9032b57cfdb94eec8ed1c32a18c58b14
Autor:
Yuji Kibe, Kazuya Motomura, Fumiharu Ohka, Kosuke Aoki, Hiroyuki Shimizu, Junya Yamaguchi, Tomohide Nishikawa, Ryuta Saito
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Isocitrate dehydrogenase wild-type (IDHwt) diffuse astrocytomas feature highly infiltrative patterns, such as a gliomatosis cerebri growth pattern with widespread involvement. Among these tumors, localized IDHwt histologically diffuse astroc
Externí odkaz:
https://doaj.org/article/beeff8d37e5b4693a460339ccf8eee1a
Autor:
Lushun Chalise, Akira Kato, Masasuke Ohno, Sachi Maeda, Akane Yamamichi, Shunichiro Kuramitsu, Satoshi Shiina, Hiromi Takahashi, Sachiko Ozone, Junya Yamaguchi, Yukinari Kato, Yumi Rockenbach, Atsushi Natsume, Tomoki Todo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 26, Iss , Pp 265-274 (2022)
Glioblastoma is a devastating malignant brain tumor with a poor prognosis despite standard therapy. Podoplanin (PDPN), a type I transmembrane mucin-like glycoprotein that is overexpressed in various cancers, is a potential therapeutic target for the
Externí odkaz:
https://doaj.org/article/245c987ac1fb490c848f5a0ad8a05f69
Autor:
Daisetsu Aoyama, Shinsuke Miyazaki, Kanae Hasegawa, Ryohei Nomura, Shota Kakehashi, Moe Mukai, Machiko Miyoshi, Junya Yamaguchi, Yusuke Sato, Yuichiro Shiomi, Hiroyuki Ikeda, Kentaro Ishida, Hiroyasu Uzui, Hiroshi Tada
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundMechanisms underlying atrial fibrillation (AF) are widely complex and vary tremendously among individuals.ObjectivesThis retrospective study aimed to investigate the association between AF activation patterns and clinical outcomes post-abla
Externí odkaz:
https://doaj.org/article/549abe38428b4a38a1eb8feedb8cb4e0
Autor:
Yoshitaka Nagashima, Yusuke Nishimura, Kaoru Eguchi, Junya Yamaguchi, Shoichi Haimoto, Fumiharu Ohka, Masakazu Takayasu, Ryuta Saito
Publikováno v:
Neurospine, Vol 19, Iss 2, Pp 262-271 (2022)
The study of genetic alterations and molecular biology in central nervous system (CNS) tumors has improved the accuracy of estimations of patient prognosis and tumor categorization. Therefore, the updated 2021 World Health Organization (WHO) classifi
Externí odkaz:
https://doaj.org/article/0482ffc89949418db1b9828f4f3b275d
Autor:
Yuji Kibe, Kuniaki Tanahashi, Kazuhiro Ohtakara, Yuka Okumura, Fumiharu Ohka, Kazuhito Takeuchi, Yuichi Nagata, Kazuya Motomura, Sho Akahori, Akihiro Mizuno, Hiroo Sasaki, Hiroyuki Shimizu, Junya Yamaguchi, Tomohide Nishikawa, Kenji Yokota, Ryuta Saito
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Eccrine spiradenocarcinoma (SC), also known as malignant eccrine spiradenoma, is a rare malignant cutaneous adnexal neoplasm arising from long-standing benign eccrine spiradenoma. Malignant skin tumors rarely show direct intracran
Externí odkaz:
https://doaj.org/article/151848dd591046cca63b5d013900407b
Autor:
Shinsuke Miyazaki, Kanae Hasegawa, Kazuya Yamao, Eri Ishikawa, Moe Mukai, Daisetsu Aoyama, Minoru Nodera, Junya Yamaguchi, Yuichiro Shiomi, Naoto Tama, Hiroyuki Ikeda, Yoshitomo Fukuoka, Kentaro Ishida, Hiroyasu Uzui, Yoshito Iesaka, Hiroshi Tada
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Left atrial roof-dependent tachycardias (LARTs) are common macroreentrant atrial tachycardias (ATs). We sought to characterize clinical LARTs using an ultra-high resolution mapping system. Methods This study included 22 consecutiv
Externí odkaz:
https://doaj.org/article/7faf2967476d40ba88bf5bf2b77f88bf
Autor:
Sachi Maeda, Fumiharu Ohka, Yusuke Okuno, Kosuke Aoki, Kazuya Motomura, Kazuhito Takeuchi, Hironao Kusakari, Nobuyuki Yanagisawa, Shinya Sato, Junya Yamaguchi, Kuniaki Tanahashi, Masaki Hirano, Akira Kato, Hiroyuki Shimizu, Yotaro Kitano, Shintaro Yamazaki, Shinji Yamashita, Hideo Takeshima, Keiko Shinjo, Yutaka Kondo, Toshihiko Wakabayashi, Atsushi Natsume
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-12 (2020)
Abstract Diffuse midline glioma, H3 K27M-mutant is a lethal brain tumor located in the thalamus, brain stem, or spinal cord. H3 K27M encoded by the mutation of a histone H3 gene such as H3F3A plays a pivotal role in the tumorigenesis of this type of
Externí odkaz:
https://doaj.org/article/6022ac32f68642d68773d237f5291135