Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Junya Ning"'
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Colorectal cancer (CRC) is one of the malignant tumors with the highest morbidity and mortality and poor prognosis. The mammalian gene family of Cab45/reticulocalbin/ERC-45/calumenin (CREC) consists of RCN1, RCN2, RCN3, SDF4 and CALU. Althou
Externí odkaz:
https://doaj.org/article/a1d5b15e9cb14673b821acf4a3f07218
Autor:
Junya Ning, Jie Hao, Fengli Guo, Xiukun Hou, Lijuan Li, Jinmiao Wang, Shoujun Wang, Ying Gao, Xiangqian Zheng, Ming Gao
Publikováno v:
Translational Oncology, Vol 36, Iss , Pp 101747- (2023)
Head and neck squamous cell carcinomas (HNSCC) are at a high risk of recurrence and multimodal therapy have not significantly improved survival in recent decades. Although immune checkpoint inhibitors (ICIs) are effective in a small proportion of HNS
Externí odkaz:
https://doaj.org/article/5997fdff70ac4357ab5b06528cd20ade
Activation of GRP78 ATPase suppresses A549 lung cancer cell migration by promoting ITGB4 degradation
Publikováno v:
Cell Adhesion & Migration, Vol 16, Iss 1, Pp 107-114 (2022)
Hypochlorous acid (HOCl) is an essential signal molecule in cancer cells. Activated GRP78 ATPase by a HOCl probe named ZBM-H inhibits lung cancer cell growth. However, the role and underlying mechanism of GRP78 ATPase in lung cancer cell migration ha
Externí odkaz:
https://doaj.org/article/90f7933d011741edb4173909a20f181a
Autor:
Lijuan Gao, Ruimin Ren, Jing Shen, Jiayi Hou, Junya Ning, Yanlin Feng, Meiyue Wang, Lifei Wu, Yaojun Sun, Huang Wang, Deping Wang, Jimin Cao
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Bladder cancer (BLCA) is one of the most common genitourinary malignancies in the world, but its pathogenic genes have not been fully identified and the treatment outcomes are still unsatisfactory. Although the members of 2', 5'-o
Externí odkaz:
https://doaj.org/article/cee5b734a3554374b36d6c823800580c
Publikováno v:
EBioMedicine, Vol 41, Iss , Pp 702-710 (2019)
The transforming growth factor β (TGF-β) superfamily participates in tumour proliferation, apoptosis, differentiation, migration, invasion, immune evasion and extracellular matrix remodelling. Genetic deficiency in distinct components of TGF-β and
Externí odkaz:
https://doaj.org/article/51618d270c694e7aacc36a95b9e13e02
Autor:
Pei Xiao, Xinxin Long, Lijie Zhang, Yingnan Ye, Jincheng Guo, Pengpeng Liu, Rui Zhang, Junya Ning, Wenwen Yu, Feng Wei, Jinpu Yu
Publikováno v:
OncoImmunology, Vol 7, Iss 7 (2018)
We previously demonstrated that neurotensin (NTS) induces local inflammation and promotes tumor invasion in hepatocellular carcinoma (HCC). However, the underlying molecular mechanisms are not clear. In this study, positive correlations between NTS a
Externí odkaz:
https://doaj.org/article/143e05ac443640158fe3bb3d1d4fa1e5
Autor:
Xiao Zhang, Rui Zhang, Pengpeng Liu, Runjiao Zhang, Junya Ning, Yingnan Ye, Wenwen Yu, Jinpu Yu
Publikováno v:
Cancers; Volume 14; Issue 3; Pages: 835
Cancers, Vol 14, Iss 835, p 835 (2022)
Cancers, Vol 14, Iss 835, p 835 (2022)
The flippase ATPase class I type 8b member 1 (ATP8B1) is essential for maintaining the stability and polarity of the epithelial membrane and can translocate specific phospholipids from the outer membrane to the inner membrane of the cell. Although AT
ZBM-H-induced activation of GRP78 ATPase promotes apoptosis via annexin A7 in A549 lung cancer cells
Autor:
Junya Ning, Xiaotan Wang, Nan Li, Xiaoling Cui, Na Li, Baoxiang Zhao, Junying Miao, Zhaomin Lin
Publikováno v:
Journal of cellular biochemistryREFERENCES. 123(4)
Hypochlorous acid (HOCl) is an essential signal for the regulation of cancer cell fate, including autophagy and apoptosis. HOCl regulated autophagy by affecting the oxidation modification of glucose-regulated protein 78 (GRP78) and the activity of GR
Publikováno v:
EBioMedicine
EBioMedicine, Vol 41, Iss, Pp 702-710 (2019)
EBioMedicine, Vol 41, Iss, Pp 702-710 (2019)
The transforming growth factor β (TGF-β) superfamily participates in tumour proliferation, apoptosis, differentiation, migration, invasion, immune evasion and extracellular matrix remodelling. Genetic deficiency in distinct components of TGF-β and
Autor:
Yingnan Ye, Guoguang Ying, Hui Li, Xiubao Ren, Yi Zhao, Gang Zhao, Hailong Wang, Pengpeng Liu, Dechao Bu, Jinpu Yu, Junya Ning, Tianqiang Song, Wenwen Yu
Publikováno v:
Mol Ther
The transforming growth factor-beta (TGF-β) signaling pathway is the predominant cytokine signaling pathway in the development and progression of hepatocellular carcinoma (HCC). Bone morphogenetic protein (BMP), another member of the TGF-β superfam