Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Junya Hayase"'
Autor:
Tsubasa Sakurai, Sachiko Kamakura, Junya Hayase, Akira Kohda, Masafumi Nakamura, Hideki Sumimoto
Publikováno v:
The Journal of biological chemistry. 298(10)
The adhesion family of G protein-coupled receptors (GPCRs) is defined by an N-terminal large extracellular region that contains various adhesion-related domains and a highly-conserved GPCR-autoproteolysis-inducing (GAIN) domain, the latter of which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894a9f6dea7331e8d96f3c77cd6468ee
https://pubmed.ncbi.nlm.nih.gov/36089063
https://pubmed.ncbi.nlm.nih.gov/36089063
Autor:
Hideki Sumimoto, Satoru Yuzawa, Kei Miyano, Hiroki Takayanagi, Sachiko Kamakura, Kanako Chishiki, Junya Hayase
Publikováno v:
J Biol Chem
Proper mitotic spindle orientation requires that astral microtubules are connected to the cell cortex by the microtubule-binding protein NuMA, which is recruited from the cytoplasm. Cortical recruitment of NuMA is at least partially mediated via dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5338735509504f65ac1a462c72be7b1d
https://doi.org/10.1074/jbc.ra119.011457
https://doi.org/10.1074/jbc.ra119.011457
Autor:
Sachiko Kamakura, Akira Kohda, Hideki Sumimoto, Junya Hayase, Vlad Tocan, Motoyuki Kohjima, Shouichi Ohga
Publikováno v:
The Journal of Biological Chemistry
Hepatocytes differ from columnar epithelial cells by their multipolar organization, which follows the initial formation of central lumen-sharing clusters of polarized cells as observed during liver development and regeneration. The molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6d023e4f5fb8ae6bce49a76816f4b6
https://doi.org/10.1016/j.jbc.2021.101354
https://doi.org/10.1016/j.jbc.2021.101354
Autor:
Tocan, Vlad1, Junya Hayase1, Sachiko Kamakura1, Akira Kohda1, Shouichi Ohga2, Motoyuki Kohjima1,3, Hideki Sumimoto1 hsumi@med.kyushu-u.ac.jp
Publikováno v:
Journal of Biological Chemistry. Dec2021, Vol. 297 Issue 6, p1-19. 19p.
Autor:
Kanako Chishiki, Hideki Sumimoto, Sachiko Kamakura, Junya Hayase, Kei Miyano, Akira Kohda, Takuya Kiyohara
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 23(6)
Transmembrane glycoproteins, synthesized at the endoplasmic reticulum (ER), generally reach the Golgi apparatus in COPII-coated vesicles en route to the cell surface. Here, we show that the bona fide nonglycoprotein Nox5, a transmembrane superoxide-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e927a3dcb3fc60d6b811379932a340
https://pubmed.ncbi.nlm.nih.gov/29718541
https://pubmed.ncbi.nlm.nih.gov/29718541
Autor:
Ryoichi Takayanagi, Hideki Sumimoto, Sachiko Kamakura, Yoshinori Fukui, Yuko Iwakiri, Masatoshi Nomura, Junya Hayase, Akihiko Nishikimi
Publikováno v:
Developmental Cell. 26(3):292-302
SummarySuccessful chemotaxis requires not only increased motility but also sustained directionality. Here, we show that, during neutrophil chemotaxis via receptors coupled with the Gi family of heterotrimeric G proteins, directional movement is regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227d7dd078bab3c17586a33f955f2d60
Publikováno v:
Biochemical and Biophysical Research Communications. 435:414-419
The cytosolic protein Ric-8A acts as a guanine nucleotide exchange factor for Gα subunits of the Gi, Gq, and G12/13 classes of heterotrimeric G protein in vitro, and is also known to increase the amounts of these Gα proteins in vivo. The mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d8c7a07b42408fc92f4b21699336d8
https://doi.org/10.1016/j.bbrc.2013.04.103
https://doi.org/10.1016/j.bbrc.2013.04.103
Publikováno v:
Biochemical Journal. 451:195-204
Bipolar spindle assembly in mitotic cells is a prerequisite to ensure correct alignment of chromosomes for their segregation to each daughter cell; spindle microtubules are tethered at plus ends to chromosomes and focused at minus ends to either of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0cca63fbc53c26266112fb30d024259
https://doi.org/10.1042/bj20121447
https://doi.org/10.1042/bj20121447
The WD40 protein Morg1 facilitates Par6–aPKC binding to Crb3 for apical identity in epithelial cells
Autor:
Takashi Ito, Sachiko Kamakura, Hideki Sumimoto, Tomoko Izaki, Junya Hayase, Yuko Iwakiri, Yoshihiro Yamaguchi
Publikováno v:
The Journal of Cell Biology
Par6–aPKC recruitment to the premature apical membrane through Morg1 interaction with Par6 is required for definition of apical identity of epithelial cells.
Formation of apico-basal polarity in epithelial cells is crucial for both morphogenes
Formation of apico-basal polarity in epithelial cells is crucial for both morphogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5697c30770cf31c639e80cfcc362f59
https://doi.org/10.1083/jcb.201208150
https://doi.org/10.1083/jcb.201208150
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 22(3)
Correct cyst morphogenesis of epithelial cells requires apical-basal polarization, which is partly regulated by mitotic spindle orientation, a process dependent on the heterotrimeric G protein subunit Gαi and its binding protein LGN. Here, we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6184464269bf9c11b5ee5271d6473dc6
https://pubmed.ncbi.nlm.nih.gov/28185378
https://pubmed.ncbi.nlm.nih.gov/28185378