Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Junya Chiba"'
Publikováno v:
The Journal of Organic Chemistry. 87:10825-10835
Publikováno v:
The Journal of organic chemistry. 87(16)
We created chiral assemblies of planar and achiral macrocycles by saccharide recognition. To achieve this, we synthesized stackable
Publikováno v:
European Journal of Organic Chemistry. 2022
Publikováno v:
The Journal of Organic Chemistry. 85:2666-2671
Halogenated 2-aminopyridine was attached to the acetylene terminal of ethynyl C-2-deoxy-β-d-ribofuranoside as a nucleobase substitute, and then, the C-nucleoside was incorporated into natural DNAs. The resulting chimeric DNA constructed double helic
Publikováno v:
ChemBioChem. 20:1945-1952
We report enzymatic phosphorylation and additive-free ligation of DNAs containing unnatural C-nucleotide residues through the action of T4 polynucleotide kinase and T4 DNA ligase. The artificial units are each made up of an alkynyl deoxyribose compon
Autor:
Tsukasa Kaneko, Junya Chiba, Yusuke Hotta, Ryuji Hayashi, Takenori Tomohiro, Akito Yamamoto, Shota Morimoto
Publikováno v:
Chemistry – An Asian Journal. 14:398-402
We developed a novel diazirine-based photolabeling agent having a (coumarin-4-yl)methyl ester scaffold, which exhibited multiple photochemical properties of crosslinking, fluorogenicity and cleavage. These properties can be kinetically regulated via
Publikováno v:
The Journal of organic chemistry. 85(4)
Halogenated 2-aminopyridine was attached to the acetylene terminal of ethynyl
Publikováno v:
Tetrahedron Letters. 60:1611-1613
The synthesis of sulfonylguanidines from N,N,N',N'-tetramethylthiourea and sulfonyl azides is described. This method serves as an alternative route for generating sulfonylguanidines via the use of stable starting materials.
Publikováno v:
International Research Journal of Pure and Applied Chemistry. 14:1-8
In this report, we describe a simple synthesis of gluconoamidinylsulfones as a new class of potential inhibitors toward glycan processing enzymes. Gluconoamidinylsulfones have a glucose-based sulfonyl amidine skeleton, thus would form a distorted hal
Autor:
Ikuhiko Nakase, Yasumaru Hatanaka, Shiroh Futaki, Keiko Kuwata, Yoshimasa Kawaguchi, Junya Chiba, Toshihide Takeuchi
Publikováno v:
Bioconjugate Chemistry. 27:1119-1130
Arginine-rich cell-penetrating peptides (CPPs) such as Tat and oligoarginine peptides have been widely used as carriers for intracellular delivery of bioactive molecules. Despite accumulating evidence for involvement of endocytosis in the cellular up