Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Junya, Toguchida"'
Autor:
Megumi Yokomizo-Goto, Nana Takenaka-Ninagawa, Chengzhu Zhao, Clémence Kiho Bourgeois Yoshioka, Mayuho Miki, Souta Motoike, Yoshiko Inada, Denise Zujur, William Theoputra, Yonghui Jin, Junya Toguchida, Makoto Ikeya, Hidetoshi Sakurai
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Ullrich congenital muscular dystrophy (UCMD) is caused by a deficiency in type 6 collagen (COL6) due to mutations in COL6A1, COL6A2, or COL6A3. COL6 deficiency alters the extracellular matrix structure and biomechanical properties
Externí odkaz:
https://doaj.org/article/f340ceaf0581411496358769fb395f06
Autor:
Chengzhu Zhao, Yoshiko Inada, Kazuya Sekiguchi, Kyosuke Hino, Megumi Nishio, Yasuhiro Yamada, Shuichi Matsuda, Junya Toguchida, Makoto Ikeya
Publikováno v:
Genes and Diseases, Vol 10, Iss 3, Pp 731-734 (2023)
Externí odkaz:
https://doaj.org/article/95ba83ae53fe4a348c39f507484b9713
Autor:
Mami Iima, Ryo Sakamoto, Takahide Kakigi, Akira Yamamoto, Bungo Otsuki, Yuji Nakamoto, Junya Toguchida, Shuichi Matsuda
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 768-775 (2023)
Purpose: To evaluate the usefulness of CT temporal subtraction (TS) images for detecting emerging or growing ectopic bone lesions in fibrodysplasia ossificans progressiva (FOP). Materials and Methods: Four patients with FOP were retrospectively inclu
Externí odkaz:
https://doaj.org/article/cd3d4167d5e541dea0e1d2252b6e04e6
Autor:
Shunsuke Kawai, Junko Sunaga, Sanae Nagata, Megumi Nishio, Masayuki Fukuda, Takeshi Kamakura, Liping Sun, Yonghui Jin, Satoko Sakamoto, Akira Watanabe, Shuichi Matsuda, Taiji Adachi, Junya Toguchida
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Although the formation of bone-like nodules is regarded as the differentiation process from stem cells to osteogenic cells, including osteoblasts and osteocytes, the precise biological events during nodule formation are unknown. Here we perf
Externí odkaz:
https://doaj.org/article/dbb57962a6144ea8b83bc0dd40be197a
Autor:
Hirotsugu Maekawa, Yonghui Jin, Megumi Nishio, Shunsuke Kawai, Sanae Nagata, Takeshi Kamakura, Hiroyuki Yoshitomi, Akira Niwa, Megumu K. Saito, Shuichi Matsuda, Junya Toguchida
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-15 (2022)
Abstract Background Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized by progressive heterotopic ossification (HO) in soft tissues due to a heterozygous mutation of the ACVR1A gene (FOP-ACVR1A), which erroneously tra
Externí odkaz:
https://doaj.org/article/1a29b45a74264b83b9eb2587ec53abff
Autor:
Takeshi Kamakura, Yonghui Jin, Megumi Nishio, Sanae Nagata, Masayuki Fukuda, Liping Sun, Shunsuke Kawai, Junya Toguchida
Publikováno v:
JBMR Plus, Vol 7, Iss 5, Pp n/a-n/a (2023)
ABSTRACT Collagen X is a non‐fibril collagen produced by hypertrophic chondrocytes and was believed to associate with the calcification process of growth plate cartilage. The homozygous loss of Col10a1 gene in mice, however, demonstrated no remarka
Externí odkaz:
https://doaj.org/article/44b157d147da47c9aeba1708c52fff2d
Autor:
Hirotsugu Maekawa, Shunsuke Kawai, Megumi Nishio, Sanae Nagata, Yonghui Jin, Hiroyuki Yoshitomi, Shuichi Matsuda, Junya Toguchida
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract Background Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal-dominant disease characterized by heterotopic ossification (HO) in soft tissues and caused by a mutation of the ACVR1A/ALK2 gene. Activin-A is a key molecule for init
Externí odkaz:
https://doaj.org/article/ec452d0b9c2c4ed4a7d2c0f47ad7cdca
Autor:
Tomoki Aoyama, MD, PhD, Koji Goto, MD, PhD, Ryosuke Ikeguchi, MD, PhD, Manabu Nankaku, RPT, PhD, Katsuyuki Madoba, RPT, Momoko Nagai-Tanima, RPT, PhD, Akira Ito, RPT, PhD, Ryosuke Kakinoki, MD, PhD, Takashi Nakamura, MD, PhD, Shuichi Matsuda, MD, PhD, Junya Toguchida, MD, PhD
Publikováno v:
Archives of Rehabilitation Research and Clinical Translation, Vol 4, Iss 1, Pp 100179- (2022)
Objective: To assess the status of 10 patients with advanced osteonecrosis of the femoral head who underwent mesenchymal stromal cell transplants and a 12-week rehabilitation program 10 years earlier. Design: Retrospective study. Setting: University
Externí odkaz:
https://doaj.org/article/b5be7ff59cce41a298c81b38f0602a37
Autor:
Liping Sun, Yonghui Jin, Megumi Nishio, Makoto Watanabe, Takeshi Kamakura, Sanae Nagata, Masayuki Fukuda, Hirotsugu Maekawa, Shunsuke Kawai, Takuya Yamamoto, Junya Toguchida
Publikováno v:
Life Science Alliance; May2024, Vol. 7 Issue 5, p1-17, 17p
Autor:
Shingo Komura, Kenji Ito, Sho Ohta, Tomoyo Ukai, Mio Kabata, Fumiaki Itakura, Katsunori Semi, Yutaka Matsuda, Kyoichi Hashimoto, Hirofumi Shibata, Masamitsu Sone, Norihide Jo, Kazuya Sekiguchi, Takatoshi Ohno, Haruhiko Akiyama, Katsuji Shimizu, Knut Woltjen, Manabu Ozawa, Junya Toguchida, Takuya Yamamoto, Yasuhiro Yamada
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
The EWS-ATF1 fusion gene causes clear cell sarcoma (CCS). Here, the authors show that the downstream effects of EWS-ATF1 expression are strictly context dependent, and reveal the cell of origin for CCS to be Tppp3-expressing cells in peripheral nerve
Externí odkaz:
https://doaj.org/article/d6a0a59accc9488fa4d118ffc7d1f1f9