Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Junya, Hatanaka"'
Autor:
Toshiyuki Tanaka, Hiroyuki Miyoshi, Kazuki Kuriyama, Shizuo Yamada, Yoshiki Seto, Tatsuya Nakamura, Atushi Uchida, Junya Hatanaka, Satomi Onoue
Publikováno v:
PharmaNutrition. 3:153-159
The major purpose of the present study was to clarify the physicochemical and nutraceutical properties of self-nanoemulsifying particles of coenzyme Q10 (CoQ10/SNEP). Nanoemulsion preconcentrate, containing CoQ10, medium-chain triglyceride, sucrose e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::512178152cad45391f8be05b24e1a66e
https://doi.org/10.1016/j.phanu.2015.05.001
https://doi.org/10.1016/j.phanu.2015.05.001
Autor:
Junya Hatanaka, Kazuki Kuriyama, Satomi Onoue, Shizuo Yamada, Toshiyuki Tanaka, Masashi Kato, Atushi Uchida, Yoshiki Seto, Hiroyuki Miyoshi, Tatsuya Nakamura
Publikováno v:
European Journal of Pharmaceutical Sciences. 46:492-499
The present study was undertaken to develop a solid self-emulsifying drug delivery system of coenzyme Q(10) (CoQ(10)/s-SEDDS) with high photostability and oral bioavailability. The CoQ(10)/s-SEDDS was prepared by spray-drying an emulsion preconcentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5048a0a3b86f5f38cf3b66d54f83be1c
https://doi.org/10.1016/j.ejps.2012.03.015
https://doi.org/10.1016/j.ejps.2012.03.015
Autor:
Yukiko Shinme, Atsushi Uchida, Kazuki Kuriyama, Shizuo Yamada, Junya Hatanaka, Shinya Uchida, Keitatsu Kou, Satomi Onoue
Publikováno v:
Drug Metabolism and Pharmacokinetics. 26:551-558
The main purpose of the present study was to develop a novel formulation of St. John's Wort (SJW) extract with the aim of improving its pharmacokinetics and anti-nociceptive effect. Several formulations of SJW were prepared, including cyclodextrin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c0be72dad4e0ed6bcf556157009217
https://doi.org/10.2133/dmpk.dmpk-11-rg-041
https://doi.org/10.2133/dmpk.dmpk-11-rg-041
Autor:
Hina Chikamori, Shizuo Yamada, Kazuhiro Debari, Junya Hatanaka, Hideyuki Sato, Satomi Onoue, Shinya Uchida
Publikováno v:
International Journal of Pharmaceutics. 396:188-193
The main purpose of the present study is to develop a novel nano-emulsion (NE) formulation of alpha-tocopherol (alpha-TC) with enhanced oral bioavailability and pharmacological effects. Three NE formulations of alpha-TC at different loading amounts (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5e9e7ec2f968ec9f9ecc286217927a
https://doi.org/10.1016/j.ijpharm.2010.06.017
https://doi.org/10.1016/j.ijpharm.2010.06.017
Autor:
Yohei Kawabata, Junya Hatanaka, Yoshiki Seto, Shizuo Yamada, Haruki Takahashi, Satomi Onoue, Barbara N. Timmermann
Publikováno v:
Journal of Pharmaceutical Sciences. 99:1871-1881
Considerable interest has been focused on curcumin due to its use to treat a wide variety of disorders, however, the therapeutic potential of curcumin could often be limited by its poor solubility, bioavailability, and photostability. To overcome the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7508fc2dcd7054430434e4b65265ddcb
https://doi.org/10.1002/jps.21964
https://doi.org/10.1002/jps.21964
Publikováno v:
International Journal of Pharmaceutics. 363:112-117
Coenzyme Q(10) (CoQ(10)) has been used as a drug for chronic heart failure. Furthermore, various biological effects of CoQ(10) have also been applied for food supplements and cosmetics. However, CoQ(10) was found to be poorly soluble in water, so tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1ac61ab318d671b3b9a790752c3c4b
https://doi.org/10.1016/j.ijpharm.2008.07.019
https://doi.org/10.1016/j.ijpharm.2008.07.019
Autor:
Satomi, Onoue, Atushi, Uchida, Kazuki, Kuriyama, Tatsuya, Nakamura, Yoshiki, Seto, Masashi, Kato, Junya, Hatanaka, Toshiyuki, Tanaka, Hiroyuki, Miyoshi, Shizuo, Yamada
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 46(5)
The present study was undertaken to develop a solid self-emulsifying drug delivery system of coenzyme Q(10) (CoQ(10)/s-SEDDS) with high photostability and oral bioavailability. The CoQ(10)/s-SEDDS was prepared by spray-drying an emulsion preconcentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04c414d73bd283ec4c6f1473411f9d51
https://pubmed.ncbi.nlm.nih.gov/22498005
https://pubmed.ncbi.nlm.nih.gov/22498005
Liposomal formulations of glucagon-like peptide-1: improved bioavailability and anti-diabetic effect
Autor:
Junko Hanato, Shizuo Yamada, Junya Hatanaka, Takahiro Mizumoto, Kazuki Kuriyama, Satomi Onoue, Kazuhiro Debari
Publikováno v:
International journal of pharmaceutics. 382(1-2)
Glucagon-like peptide-1 (GLP-1), an incretin hormone, is recognized to be potent drug candidate for treatment of diabetes, however its clinical application has been highly limited, because of rapid enzymatic degradation by dipeptidyl-peptidase IV. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340632262746edd9b305af2847512bb7
https://pubmed.ncbi.nlm.nih.gov/19698772
https://pubmed.ncbi.nlm.nih.gov/19698772