Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Junya, Awata"'
Autor:
Chun Chou, Gregory L. Martin, Gayani Perera, Junya Awata, Amy Larson, Robert Blanton, Michael T. Chin
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/44ff253957e346fb8924810c3dcff37d
Autor:
Jean Mukherjee, Celinia A. Ondeck, Jacqueline M. Tremblay, Jacob Archer, Michelle Debatis, Alexa Foss, Junya Awata, Jesse H. Erasmus, Patrick M. McNutt, Charles B. Shoemaker
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Single domain antibodies (sdAbs), also called nanobodies, have substantial biophysical advantages over conventional antibodies and are increasingly being employed as components of immunotherapeutic agents. One particularly favorable property
Externí odkaz:
https://doaj.org/article/fbf6a19e8929440a86eeb6f344288f44
Autor:
Chun Chou, Gregory L. Martin, Gayani Perera, Junya Awata, Amy Larson, Robert Blanton, Michael T. Chin
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disorder affecting 1 in 500 people in the general population. Characterized by asymmetric left ventricular hypertrophy, cardiomyocyte disarray and cardiac fibrosis, HCM is
Externí odkaz:
https://doaj.org/article/70a1450d9b0f468c9509965ddb5eba4e
Autor:
Kay D. Everett, Lija Swain, Lara Reyelt, Monica Majumdar, Xiaoying Qiao, Shreyas Bhave, Mary Warner, Elena Mahmoudi, Michael T. Chin, Junya Awata, Navin K. Kapur
Publikováno v:
JACC: Basic to Translational Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc1c8025f28b7f78ba19e6e007ff490c
https://doi.org/10.1016/j.jacbts.2023.01.004
https://doi.org/10.1016/j.jacbts.2023.01.004
Publikováno v:
Cardiology and cardiovascular medicine. 6(4)
End stage, nonobstructive hypertrophic cardiomyopathy (HCM) is an intractable condition with no disease-specific therapies. To gain insights into the pathogenesis of nonobstructive HCM, we performed single nucleus RNA-sequencing (snRNA-seq) on human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42da5711f08330a84073b565c2fa702e
https://pubmed.ncbi.nlm.nih.gov/36237479
https://pubmed.ncbi.nlm.nih.gov/36237479
Autor:
Chun Chou, Gregory Martin, Gayani Perera, Junya Awata, Robert M Blanton, Xuehong Cao, Abdullah Alissa, Christopher Madias, Jonas B Galper, Michael T Chin
Publikováno v:
Circulation Research. 131
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disorder affecting 1 in 500 people in the general population. Characterized by asymmetric left ventricular hypertrophy, cardiomyocyte disarray, cardiac fibrosis and increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c615f5a9310a864d4a891a96f58562bd
https://doi.org/10.1161/res.131.suppl_1.p2011
https://doi.org/10.1161/res.131.suppl_1.p2011
Autor:
Jean Mukherjee, Celinia A. Ondeck, Jacqueline M. Tremblay, Jacob Archer, Michelle Debatis, Alexa Foss, Junya Awata, Jesse H. Erasmus, Patrick M. McNutt, Charles B. Shoemaker
Single domain antibodies (sdAbs) have substantial biophysical advantages over conventional antibodies and are increasingly being employed as components of immunotherapeutic agents. One particularly favorable property is the ability to link different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdfdbdec31338c25181c007cae6a5294
https://doi.org/10.21203/rs.3.rs-1565002/v1
https://doi.org/10.21203/rs.3.rs-1565002/v1
Autor:
Michael Chin, Christina Codden, Amy Larson, Gayani Perera, Jason Laird, Rebecca Batorsky, Junya Awata
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3186e034f21c700a218ad68d5eeb441a
https://doi.org/10.1016/j.yjmcc.2022.08.090
https://doi.org/10.1016/j.yjmcc.2022.08.090
Autor:
Robert M. Blanton, Gregory Martin, Mark Aronovitz, Lauren Richey, Wei-Ming Chien, Corinne J Thomas, Kelly Tam, Michael T. Chin, Douglas Strathdee, Junya Awata, Ana Dinca
Publikováno v:
Circulation Research. 125
Barth syndrome (BTHS) is an X-linked recessive disease where patients most commonly die from cardiomyopathy-induced heart failure before middle age. BTHS is caused by mutations in the tafazzin (TAZ) gene, resulting in defective TAZ protein. TAZ is an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::810003d8c1726858ddd487996b6cd3a0
https://doi.org/10.1161/res.125.suppl_1.113
https://doi.org/10.1161/res.125.suppl_1.113
Autor:
Raqual Bower, Kangkang Song, Mary E. Porter, Junya Awata, George B. Witman, Douglas Tritschler, Daniela Nicastro
Publikováno v:
Journal of Biological Chemistry. 290:5341-5353
Cryo-electron tomography (cryo-ET) has reached nanoscale resolution for in situ three-dimensional imaging of macromolecular complexes and organelles. Yet its current resolution is not sufficient to precisely localize or identify most proteins in situ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436b82c74571b3c3177b1549f5658b8b
https://doi.org/10.1074/jbc.m114.626556
https://doi.org/10.1074/jbc.m114.626556