Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Junxiong Chen"'
Autor:
Mengchen Shi, Linsen Ye, Lu Zhao, Lingyuan He, Junxiong Chen, Jingdan Zhang, Yixi Su, Haiyan Dong, Jiaqi Liu, Liumei Liang, Wenwen Zheng, Yanhong Xiao, Huanliang Liu, Xiangling Yang, Zihuan Yang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Extracellular ATP–AMP–adenosine metabolism plays a pivotal role in modulating tumor immune responses. Previous studies have shown that the conversion of ATP to AMP is primarily catalysed by Ectonucleoside triphosphate diphosph
Externí odkaz:
https://doaj.org/article/e77c4194627e4e3e91a8edb8b54a6050
Publikováno v:
PeerJ, Vol 12, p e17422 (2024)
Background There is a paucity of knowledge concerning the psychological variables that serve to facilitate the connection between physical activity and self-efficacy, and the factors capable of moderating these pathways. This study aimed to examine t
Externí odkaz:
https://doaj.org/article/7d9099980e9144d492e8f7e1d0f70427
Autor:
Yanchun Feng, Yingming Jiang, Jun Liu, Jiaqi Liu, Mengchen Shi, Junxiong Chen, Jingdan Zhang, Yu Tian, Xiangling Yang, Huanliang Liu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Autophagy is involved in nasopharyngeal carcinoma (NPC) radioresistance. Replication protein A 1 (RPA1) and RPA3, substrates of the RPA complex, are potential therapeutic targets for reversing NPC radioresistance. Nevertheless, th
Externí odkaz:
https://doaj.org/article/1659b5ed69f34b2dbb720483299e2e17
Autor:
Dongni Lin, Kaihao Yan, Lingyun Chen, Junxiong Chen, Jianing Xu, Zijing Xie, Zhujun Li, Shuo Lin, Jinghuan Li, Zhenzhou Chen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The benefits of hypoxia for maintaining the stemness of cultured human bone marrow-derived endothelial progenitor cells (BM EPCs) have previously been demonstrated but the mechanisms responsible remain unclear. Growing evidences suggest that
Externí odkaz:
https://doaj.org/article/61dc5f05adb041f6b7e2e3a142bf00b3
Autor:
Rui-Xian Liu, Chuangyu Wen, Weibiao Ye, Yewei Li, Junxiong Chen, Qian Zhang, Weiqian Li, Wanfei Liang, Lili Wei, Jingdan Zhang, Ka-Wo Chan, Xueqin Wang, Xiangling Yang, Huanliang Liu
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106140- (2023)
Summary: Antibody-secreting B cells have long been considered the central element of gut homeostasis; however, tumor-associated B cells in human colorectal cancer (CRC) have not been well characterized. Here, we show that the clonotype, phenotype, an
Externí odkaz:
https://doaj.org/article/dd1f2ddf26e4425aa4d4cc6b1495143d
Autor:
Huihui Wang, Chuangyu Wen, Siyu Chen, Weiqian Li, Qiyuan Qin, Lu He, Fang Wang, Junxiong Chen, Weibiao Ye, Wende Li, Junsheng Peng, Xiangling Yang, Huanliang Liu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
There is an urgent need for novel agents for colorectal cancer (CRC) due to the increasing number of cases and drug-resistance related to current treatments. In this study, we aim to uncover the potential of chaetocin, a natural product, as a chemoth
Externí odkaz:
https://doaj.org/article/cbd34d805ee14d38897da94f6de55902
Autor:
Jiancong Hu MD, Zihan Wang BS, Junxiong Chen PhD, Zhaoliang Yu MD, Jingdan Zhang BS, Weiqian Li BS, Mengmeng Lin BS, Xiangling Yang PhD, Huanliang Liu MD, PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 20 (2021)
Inhibitor of β-catenin and T-cell factor (ICAT) was first found as a polypeptide that blocks β-catenin–TCF interaction. Abundant evidence has shown that ICAT has different functions in diverse cancers’ progression. Nevertheless, the roles it pl
Externí odkaz:
https://doaj.org/article/85d0189fcb954e288097d28a9dccf2ce
Autor:
Qiong Lou, Ruixian Liu, Xiangling Yang, Weiqian Li, Lanlan Huang, Lili Wei, Huiliu Tan, Nanlin Xiang, Kawo Chan, Junxiong Chen, Huanliang Liu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Indoleamine 2,3-dioxygenase 1 (IDO1) is a critical regulator of T cell function, contributing to immune tolerance. Upregulation of IDO1 has been found in many cancer types; however, the regulatory mechanisms and clinical significa
Externí odkaz:
https://doaj.org/article/5f6846e496bf40ae9aec075ba71233eb
Autor:
Ge Sun, Junxiong Chen, Yingjun Ding, Jonathan D. Wren, Fuyi Xu, Lu Lu, Yan Wang, Dao-wen Wang, Xin A. Zhang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Tetraspanins and integrins are integral membrane proteins. Tetraspanins interact with integrins to modulate the dynamics of adhesion, migration, proliferation, and signaling in the form of membrane domains called tetraspanin-enriched micr
Externí odkaz:
https://doaj.org/article/7f5f67533b054250bc13e8181d898746
Publikováno v:
Cellular Physiology and Biochemistry, Vol 39, Iss 2, Pp 721-739 (2016)
Background: Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acids (AA) to form epoxyeicosatrienoic acids (EETs), which exert beneficial roles in the treatment of cardiovascular diseases, but little is known about its role on adventitial rem
Externí odkaz:
https://doaj.org/article/f52e6ba188664192bb33d379acdefe6d