Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Junxiao Zhuo"'
Autor:
Zijian Zhang, Deshun Zeng, Wei Zhang, Ailin Chen, Jie Lei, Fang Liu, Bing Deng, Junxiao Zhuo, Bin He, Min Yan, Xinxing Lei, Shulan Wang, Eric W.-F. Lam, Quentin Liu, Zifeng Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-15 (2021)
Abstract Uncontrolled mitosis is one of the most important features of cancer, and mitotic kinases are thought to be ideal targets for anticancer therapeutics. However, despite numerous clinical attempts spanning decades, clinical trials for mitotic
Externí odkaz:
https://doaj.org/article/635c8173f8c740859566c26c14e0b828
Autor:
Min Yan, Bin He, Bing Deng, Jie Lei, Wei Zhang, Junxiao Zhuo, Eric W.-F. Lam, Zifeng Wang, Shulan Wang, Ailin Chen, Zijian Zhang, Fang Liu, Xinxing Lei, Deshun Zeng, Quentin Liu
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-15 (2021)
Cell Death and Disease, Vol 12, Iss 10, Pp 1-15 (2021)
Uncontrolled mitosis is one of the most important features of cancer, and mitotic kinases are thought to be ideal targets for anticancer therapeutics. However, despite numerous clinical attempts spanning decades, clinical trials for mitotic kinase-ta
Autor:
Fang Liu, Xuan Wang, Jianli Duan, Zhijie Hou, Zhouming Wu, Lingling Liu, Hanqi Lei, Dan Huang, Yifei Ren, Yue Wang, Xinyan Li, Junxiao Zhuo, Zijian Zhang, Bin He, Min Yan, Huiming Yuan, Lihua Zhang, Jinsong Yan, Shijun Wen, Zifeng Wang, Quentin Liu
Publikováno v:
Advanced Science. 9:2104823
AURKA is a potential kinase target in various malignancies. The kinase-independent oncogenic functions partially disclose the inadequate efficacy of the kinase inhibitor in a Phase III clinical trial. Simultaneously targeting the catalytic and noncat