Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Junxian Hong"'
Autor:
Mingxi Li, Yifei Ren, Zhen Qin Aw, Bo Chen, Ziqing Yang, Yuqing Lei, Lin Cheng, Qingtai Liang, Junxian Hong, Yiling Yang, Jing Chen, Yi Hao Wong, Jing Wei, Sisi Shan, Senyan Zhang, Jiwan Ge, Ruoke Wang, Jay Zengjun Dong, Yuxing Chen, Xuanling Shi, Qi Zhang, Zheng Zhang, Justin Jang Hann Chu, Xinquan Wang, Linqi Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The authors identify nanobodies from immunized alpaca with broadly neutralizing activity against SARS-CoV-1, SARS-CoV-2 variants, and major sarbecoviruses. One representative nanobody binds to a highly conserved epitope on RBD and protects K18-hACE2
Externí odkaz:
https://doaj.org/article/56dcd05d7c9842e89c47db3e1ae5a3a4
Publikováno v:
Infectious Diseases & Immunity, Vol 2, Iss 4, Pp 263-273 (2022)
Abstract. Human immunodeficiency virus (HIV)-1 infection creates a persistent latent reservoir even after antiretroviral therapy, which is the main barrier to HIV cure. One of the most explored strategies is the use of latent reversal agents (LRAs) t
Externí odkaz:
https://doaj.org/article/81857819bc374df3b3783b3981025877
Autor:
Yangyang Li, Zhisong Wang, Ying Hou, Xiaoyu Liu, Junxian Hong, Xuanling Shi, Xiaojie Huang, Tong Zhang, Xuebin Liao, Linqi Zhang
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Antiretroviral therapy can successfully suppress HIV-1 replication to undetectable levels but fails to eliminate latent and persistent HIV-1 reservoirs. Recent studies have focused on the immunomodulatory agents such as Toll-like receptor 7 and 8 (TL
Externí odkaz:
https://doaj.org/article/84763039d59843d6bfd5a3de5349592a
Autor:
Ruoke Wang, Qi Zhang, Rui Zhang, Zhen Qin Aw, Peng Chen, Yi Hao Wong, Junxian Hong, Bin Ju, Xuanling Shi, Qiang Ding, Zheng Zhang, Justin Jang Hann Chu, Linqi Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Striking number of mutations found in the spike protein of recently emerged SARS-CoV-2 Omicron subvariants BA.1, BA.2, BA.3 and BA.4/5 has raised serious concerns regarding the escape from current antibody therapies and vaccine protection. Here, we c
Externí odkaz:
https://doaj.org/article/13576e6d57a34006b3dc059820a7b2b7
Autor:
Tao Chen, Yun Huang, Junxian Hong, Xikang Wei, Fang Zeng, Jialin Li, Geting Ye, Jie Yuan, Yuhua Long
Publikováno v:
Marine Drugs, Vol 19, Iss 1, p 12 (2020)
The latest research has indicated that anti-tumor agents with COX-2 inhibitory activity may benefit their anti-tumor efficiency. A series of sclerotiorin derivatives have been synthesized and screened for their cytotoxic activity against human lung c
Externí odkaz:
https://doaj.org/article/956e526d086a40afbe92c0ca9d79eb31
Publikováno v:
Journal of environmental management. 325
Trimethoprim (TMP), as a widely used chemotherapeutic antibiotic agent, has caused potential risks to the aquatic environment. In this study, magnetic Co-doped Fe
Autor:
Mingxi Li, Yifei Ren, Zhen Qin Aw, Bo Chen, Ziqing Yang, Yuqing Lei, Lin Cheng, Qingtai Liang, Junxian Hong, Yiling Yang, Jing Chen, Yi Hao Wong, Sisi Shan, Senyan Zhang, Jiwan Ge, Ruoke Wang, Xuanling Shi, Qi Zhang, Zheng Zhang, Justin Jang Hann Chu, Xinquan Wang, Linqi Zhang
As SARS-CoV-2 Omicron and other variants of concern continue spreading around the world, development of antibodies and vaccines to confer broad and protective activity is a global priority. Here, we report on the identification of a special group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3aa26afd5ac56a0dfc30e7a615e12216
https://doi.org/10.1101/2022.04.12.488087
https://doi.org/10.1101/2022.04.12.488087
Publikováno v:
Journal of Materials Chemistry C. 8:16083-16091
In recent years, substantial progress has been made in the synthesis of colloidal CsPbX3 (X = Cl, Br, and I) nanocrystals (NCs). However, the anion exchange reaction always synthesizes CsPbCl3 NCs with low efficiency and poor stability. Here, first,
Autor:
Sisi Shan, Shitong Luo, Ziqing Yang, Junxian Hong, Yufeng Su, Fan Ding, Lili Fu, Chenyu Li, Peng Chen, Jianzhu Ma, Xuanling Shi, Qi Zhang, Bonnie Berger, Linqi Zhang, Jian Peng
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(11)
SignificanceSARS-CoV-2 continues to evolve through emerging variants, more frequently observed with higher transmissibility. Despite the wide application of vaccines and antibodies, the selection pressure on the Spike protein may lead to further evol
Publikováno v:
Journal of Environmental Management. 325:116459