Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Junwen, Deng"'
Autor:
Jaya Manjunath, Varsha Parthasarathy, Marina Z. Joel, Junwen Deng, Emily Z. Ma, Kevin K. Lee, Thomas Pritchard, Shenghao Guo, Cissy Zhang, Madan M. Kwatra, Anne Le, Shawn G. Kwatra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Chronic pruritus of unknown origin (CPUO) is characterized by chronic itch for 6 weeks or greater without an identifiable primary cause. Studies are needed to investigate circulating blood biomarkers to elucidate disease pathogenesis. The ob
Externí odkaz:
https://doaj.org/article/1acfa06fe5514aafb864c485e9168250
Publikováno v:
Aggregate, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract Photoluminescence (PL) mechanisms of nontraditional luminogens (NTLs) have attracted great interest, and they are generally explained with intra/intermolecular through‐space conjugation (TSC) of nonconventional chromophores. Here a new con
Externí odkaz:
https://doaj.org/article/47a8e0ef153e455b86265941b42c02d5
Autor:
Hannah L. Cornman, BS, Junwen Deng, BA, Anusha Kambala, BS, Varsha Parthasarathy, BS, Sriya V. Reddy, BS, Shawn G. Kwatra, MD
Publikováno v:
JAAD International, Vol 13, Iss , Pp 74-82 (2023)
Background: Prurigo nodularis (PN) is a chronic inflammatory skin disease associated with several systemic comorbidities. However, there is lack of evidence supporting specific laboratory testing in the diagnostic workup of PN patients. Objective: To
Externí odkaz:
https://doaj.org/article/b8258fb939324468b3527e5e8fa63aa3
Autor:
Emily Z. Ma, Junwen Deng, Varsha Parthasarathy, Kevin K. Lee, Thomas Pritchard, Shenghao Guo, Cissy Zhang, Madan M. Kwatra, Anne Le, Shawn G. Kwatra
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ImportanceDisease models for atopic dermatitis (AD) have primarily focused on understanding underlying environmental, immunologic, and genetic etiologies. However, the role of metabolic mechanisms in AD remains understudied.ObjectiveTo investigate th
Externí odkaz:
https://doaj.org/article/57002ae2747249f9a2e5a2266c68fcea
Autor:
Xinlin Liu, Jiyixuan Li, Junwen Deng, Jianan Zhao, Gaoxiang Zhao, Tingting Zhang, Hongfei Jiang, Bing Liang, Dongming Xing, Jie Wang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Trophoblast cell surface antigen 2 (Trop2) exhibits limited expression in normal tissues but is over-expressed across various solid tumors. The effectiveness of anti-Trop2 antibody-drug conjugate (ADC) in managing breast cancer validates Trop2 as a p
Externí odkaz:
https://doaj.org/article/c184a8c1602e43ba94c813e54c3cd171
Autor:
Xinlin Liu, Junwen Deng, Renshuai Zhang, Jiyao Xing, Yudong Wu, Wujun Chen, Bing Liang, Dongming Xing, Jiazhen Xu, Miao Zhang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Despite the emergence of molecular targeted therapy and immune checkpoint inhibitors as standard first-line treatments for non-small cell lung cancer (NSCLC), their efficacy in some patients is limited by intrinsic and acquired resistance. Antibody-d
Externí odkaz:
https://doaj.org/article/8c72c3e2cee643778f44cc8226fecdb7
Autor:
Xinlin Liu, Linli Luan, Xi Liu, Dingwen Jiang, Junwen Deng, Jiazhen Xu, Yang Yuan, Jiyao Xing, Bingguan Chen, Dongming Xing, Haiming Huang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Human epithelial growth factor receptor-2 (HER2) plays an oncogenic role in numerous tumors, including breast, gastric, and various other solid tumors. While anti-HER2 therapies are approved for the treatment of HER2-positive tumors, a necessity pers
Externí odkaz:
https://doaj.org/article/31cb72e90bb9468aacdde98b705a3c3b
Publikováno v:
Molecules, Vol 28, Iss 16, p 5950 (2023)
Nontraditional luminogens (NTLs) do not contain any conventional chromophores (large π-conjugated structures), but they do show intrinsic photoluminescence. To achieve photoluminescence from NTLs, it is necessary to increase the extent of through-sp
Externí odkaz:
https://doaj.org/article/79152d85fd1b4334a18728946879bd8d
Autor:
Justin Choi, Zachary A. Bordeaux, Gabriella Braun, Cole Davis, Varsha Parthasarathy, Junwen Deng, Mathew T. Taylor, Anusha Kambala, Hannah Cornman, Olusola Oladipo, Martin P. Alphonse, Cameron E. West, Shawn G. Kwatra, Madan M. Kwatra
Publikováno v:
JID Innovations, Vol 3, Iss 1, Pp 100164- (2023)
UV irradiation is commonly used in murine models of skin cancers. Despite the popularity of using UVB rays to model photocarcinogenesis in animals, there is a lack of standardization in the secondary enclosures used to administer radiation. An apprai
Externí odkaz:
https://doaj.org/article/0de2062469bf49509619c9b13657c872
Autor:
Junwen Deng, Varsha Parthasarathy, Melika Marani, Zachary Bordeaux, Kevin Lee, Chi Trinh, Hannah L. Cornman, Anusha Kambala, Thomas Pritchard, Shihua Chen, Nishadh Sutaria, Olusola O. Oladipo, Madan M. Kwatra, Martin P. Alphonse, Shawn G. Kwatra
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Prurigo nodularis (PN) is a chronic, pruritic, inflammatory skin disease characterized by hyperkeratotic nodules on the trunk and extremities. While there is growing research on the immunological basis of PN, the neuropathic and structural components
Externí odkaz:
https://doaj.org/article/517c5d4160ab47cd87f1c1b94ceb0e0d