Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Junwan Fan"'
Autor:
Junwan Fan, Haowen Li, Lun Kuang, Zichen Zhao, Wenyan He, Chen Liu, Yongjun Wang, Steven Y. Cheng, Wei Chen
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Background Hedgehog signaling is essential to the regulation of embryonic development, tissue homeostasis, and stem cell self-renewal, making it a prime target for developing cancer therapeutics. Given the close link between aberrant Hedgeho
Externí odkaz:
https://doaj.org/article/054017eb11d94654ab20711938c4b523
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The first adult repopulating hematopoietic stem cells (HSCs) are found in the aorta-gonad-mesonephros (AGM) region, which are produced from hemogenic endothelial cells. Embryonic head is the other site for HSC development. Wild-type p53-induced phosp
Externí odkaz:
https://doaj.org/article/cf1bf6fb9bc946359fcef5f601c4ba39
Autor:
Yan Li, Ying Zhang, Ming Zou, Yan Feng, Wenyan He, Junwan Fan, Haowen Li, Wei-Na Jin, Jingli Cao, Yuwhen Xiu
Publikováno v:
Stroke and Vascular Neurology, Vol , Iss
Background Stroke is a devastating disease, including intracerebral haemorrhage (ICH) and ischaemic stroke. Emerging evidences indicate that systemic inflammatory cascades after stroke contribute to brain damage. However, the direct effects and featu
Externí odkaz:
https://doaj.org/article/5877ac563c9b483795b7d1c901d7c3cf
Publikováno v:
Stroke and Vascular Neurology, Vol , Iss
Stem cells (SCs) are cells with strong proliferation ability, multilineage differentiation potential and self-renewal capacity. SC transplantation represents an important therapeutic advancement for the treatment strategy of neurological diseases, bo
Externí odkaz:
https://doaj.org/article/c45c008987ca4f479a873c6ca087b3f1
Autor:
Ming Zou, Junwan Fan, Jingli Cao, Ying Zhang, Yuwhen Xiu, Wei-Na Jin, Yan Feng, Wenyan He, Haowen Li, Yan Li
Publikováno v:
Stroke and Vascular Neurology, Vol, Iss
BackgroundStroke is a devastating disease, including intracerebral haemorrhage (ICH) and ischaemic stroke. Emerging evidences indicate that systemic inflammatory cascades after stroke contribute to brain damage. However, the direct effects and featur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17171314d1c7e6c058e164cafc4b2ef1
https://doi.org/10.1136/svn-2021-000987
https://doi.org/10.1136/svn-2021-000987
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14505
Epilepsy is one of the common encephalopathies caused by sudden abnormal discharges of neurons in the brain. About 30% of patients with epilepsy are insensitive and refractory to existing antiseizure medications. The sonic hedgehog signaling pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c885dfd1e001e2ad689c4b643d97dbe6
https://doi.org/10.3390/ijms232314505
https://doi.org/10.3390/ijms232314505
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The first adult repopulating hematopoietic stem cells (HSCs) are found in the aorta-gonad-mesonephros (AGM) region, which are produced from hemogenic endothelial cells. Embryonic head is the other site for HSC development. Wild-type p53-induced phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136eef2f3c994fd1594c9bfdbd27053f
https://pubmed.ncbi.nlm.nih.gov/34604235
https://pubmed.ncbi.nlm.nih.gov/34604235
Autor:
Junwan Fan, Haowen Li, Zichen Zhao, Lun Kuang, Wenyan He, Yongjun Wang, Steven Y. Cheng, Wei Chen
Background Hedgehog signaling is essential to the regulation of embryonic development, tissue homeostasis, and stem cell self-renewal, making it a prime target for developing cancer therapeutics. Given the close link between aberrant Hedgehog signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3590384ae0201828ed317e60c4440c3f
https://doi.org/10.21203/rs.3.rs-127245/v1
https://doi.org/10.21203/rs.3.rs-127245/v1
Autor:
Junwan Fan, Yaqing Wang, Zhiheng Xu, Fei Gao, Lei Shi, Liang Liu, Feng Zhang, Hongsheng Zhang, Mei Yu
Publikováno v:
The Journal of Cell Biology
In this study, Fan et al. show that cTAGE5 interacts with the v-SNARE Sec22b to regulate proinsulin processing and COPII-dependent trafficking from the ER to the Golgi, thereby influencing glucose tolerance.
Proinsulin is synthesized in the endo
Proinsulin is synthesized in the endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17e5b91568f0ac46f2f02dfe102d977
http://europepmc.org/articles/PMC5716288
http://europepmc.org/articles/PMC5716288
Autor:
Tao Wang, Junwan Fan, Yaqing Wang, Fei Gao, Lei Shi, Mei Yu, Hongsheng Zhang, Yisheng Jiang, Liang Liu, Li Yao, Guanghou Shui, Yingchun Wang, Zhiheng Xu, Feng Zhang, Xiahe Huang, Qin Wang, Sin Man Lam, Xiaohui Zhang
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Normal neural development is essential for the formation of neuronal networks and brain function. Cutaneous T cell lymphoma-associated antigen 5 (cTAGE5)/meningioma expressed antigen 6 (MEA6) plays a critical role in the secretion of proteins. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa08bd235c1196a30979eec65e205cee
https://doi.org/10.1073/pnas.1804083115
https://doi.org/10.1073/pnas.1804083115