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Akademický článek

The role of ubiquitination and deubiquitination in the regulation of cell junctions

Autor: Junting Cai, Miranda K. Culley, Yutong Zhao, Jing Zhao

Publikováno v: Protein & Cell, Vol 9, Iss 9, Pp 754-769 (2017)

ABSTRACT Maintenance of cell junctions plays a crucial role in the regulation of cellular functions including cell proliferation, permeability, and cell death. Disruption of cell junctions is implicated in a variety of human disorders, such as inflam

Externí odkaz: https://doaj.org/article/8e5ba85282084253a1f0701e919b4ca0

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Akademický článek

AM966, an Antagonist of Lysophosphatidic Acid Receptor 1, Increases Lung Microvascular Endothelial Permeability through Activation of Rho Signaling Pathway and Phosphorylation of VE-Cadherin

Autor: Junting Cai, Jianxin Wei, Shuang Li, Tomeka Suber, Jing Zhao

Publikováno v: Mediators of Inflammation, Vol 2017 (2017)

Maintenance of pulmonary endothelial barrier integrity is important for reducing severity of lung injury. Lysophosphatidic acid (LPA) regulates cell motility, cytoskeletal rearrangement, and cell growth. Knockdown of LPA receptor 1 (LPA1) has been sh

Externí odkaz: https://doaj.org/article/abccfb681e0740e28f617d7b3d0972ac

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Induction of deubiquitinating enzyme USP50 during erythropoiesis and its potential role in the regulation of Ku70 stability

Autor: Jing Zhao, Junting Cai, Valerie Schrott, Grant C. Bullock, Yutong Zhao, Jianxin Wei

Publikováno v: Journal of investigative medicine : the official publication of the American Federation for Clinical Research

Anemia is a very common blood disorder that affects the lives of billions of people worldwide. Anemia is caused by the loss of blood, increased destruction of red blood cells (RBCs), or reduced production of RBCs. Erythropoiesis is the complex proces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0118f003e1ab257952a6aab96ef5857e
https://pubmed.ncbi.nlm.nih.gov/29101126

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AM966, an Antagonist of Lysophosphatidic Acid Receptor 1, Increases Lung Microvascular Endothelial Permeability through Activation of Rho Signaling Pathway and Phosphorylation of VE-Cadherin

Autor: Jianxin Wei, Shuang Li, Junting Cai, Tomeka Suber, Jing Zhao

Publikováno v: Mediators of Inflammation
Mediators of Inflammation, Vol 2017 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01d65087e6fcb036b047b6fad9f9e17
http://europepmc.org/articles/PMC5350330

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An Antagonist of Lysophosphatidic Acid Receptor1, Am966, Increases Pulmonary Endothelial Permeability through Activation of Ve-Cadherin

Autor: Jianxin Wei, Jing Zhao, Anastasia M. Jacko, Junting Cai

Publikováno v: Journal of Investigative Medicine. 64:965-966

Background Maintenance of pulmonary endothelial barrier integrity is important for reducing severity of lung injury. VE-cadherin is a major component of cell–cell adherens junctions in endothelium. In response to inflammatory stimuli, VE-cadherin i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::991d6d86096ba48f2ff430c577badd98
https://doi.org/10.1136/jim-2016-000120.112

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Akademický článek

Induction of deubiquitinating enzyme USP50 during erythropoiesis and its potential role in the regulation of Ku70 stability.

Autor: Junting Cai, Jianxin Wei, Schrott, Valerie, Jing Zhao, Bullock, Grant, Yutong Zhao, Cai, Junting, Wei, Jianxin, Zhao, Jing, Zhao, Yutong

Publikováno v: Journal of Investigative Medicine (Sage Publications Inc.); Jan2018, Vol. 66 Issue 1, p1-6, 6p

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