Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Junseon Min"'
Autor:
Seyed Eghtasadi, Daniel Shapiro, Sonal Deshpande, Junseon Min, David Fiflis, Dahlia Rohm, YIfan Dai, Aravind Asokan, Charles Gersbach, Ashutosh Chilkoti
Biomolecular condensates composed of proteins and RNA, known as ribonucleoprotein granules, are one approach by which cells regulate post-transcriptional gene expression. The formation of ribonucleoprotein granules typically involves the liquid-liqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5914500793d53418df22a8c8b58bf85a
https://doi.org/10.21203/rs.3.rs-1982007/v1
https://doi.org/10.21203/rs.3.rs-1982007/v1
Publikováno v:
Biomacromolecules
Valency is a fundamental principle to control macromolecular interactions and is used to target specific cell types by multivalent ligand-receptor interactions using self-assembled nanoparticle carriers. At the concentrations encountered in solid tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a66ae33aed6e2399f537dbe22992fe6
https://europepmc.org/articles/PMC9339257/
https://europepmc.org/articles/PMC9339257/
Publikováno v:
ACS nano. 14(1)
Multivalent nanoparticles that target a cell surface receptor that is overexpressed by cancer cells are a promising delivery system for cancer therapy. However, the impact of the receptor density and nanoparticle ligand valency on the cell uptake has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20840c13d35b8e0250342cfc07ad994
https://pubmed.ncbi.nlm.nih.gov/31899613
https://pubmed.ncbi.nlm.nih.gov/31899613
Publikováno v:
RSC Advances. 6:19208-19213
A polyvalent antibody-binding lumazine synthase protein cage nanoparticle (ABD–AaLS) is constructed by genetically fusing lumazine synthase and antibody-binding domains. ABD–AaLS effectively captures targeting antibodies in an orientation-control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a78e883710f9c9ef6721e66773d7660a
https://doi.org/10.1039/c6ra00233a
https://doi.org/10.1039/c6ra00233a
Publikováno v:
Biomacromolecules. 15:3794-3801
Protein cage nanoparticles are excellent candidates for use as multifunctional delivery nanoplatforms because they are built from biomaterials and have a well-defined structure. A novel protein cage nanoparticle, encapsulin, isolated from thermophili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b83852defea7fc75591943eff4ff94d
https://doi.org/10.1021/bm501066m
https://doi.org/10.1021/bm501066m
Publikováno v:
Macromolecular Bioscience. 14:557-564
Genetic and chemical engineering approaches are used to employ P22 viral capsids as nanoplatforms for developing an efficient delivery vehicle. Catechol ligands are chemically attached to the interior surface of P22 viral capsid for subsequent encaps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c6949df0e1adc726120a298465eec73
https://doi.org/10.1002/mabi.201300401
https://doi.org/10.1002/mabi.201300401
Publikováno v:
RSC Adv.. 4:48596-48600
Lumazine synthase protein cage nanoparticle isolated from Aquifex aeolicus (AaLS) is developed as a modular delivery nanoplatform that genetically acquires either tumor vasculature targeting peptides or hepatocellular carcinoma cell surface targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2a1e0d6bdfc329d3c2e9f775c5485d0
https://doi.org/10.1039/c4ra10187a
https://doi.org/10.1039/c4ra10187a
Publikováno v:
Scientific Reports
SCIENTIFIC REPORTS(6)
SCIENTIFIC REPORTS(6)
We construct a novel recombinant secondary antibody mimic, GST-ABD, which can bind to the Fc regions of target-bound primary antibodies and acquire multiple HRPs simultaneously. We produce it in tenth of mg quantities with a bacterial overexpression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53cb7b309d336c53d189ae2f1631cd0
https://doi.org/10.1038/srep24159
https://doi.org/10.1038/srep24159
Autor:
Junseon Min, Hyun-Woo Rhee, Jisu Lee, Eun Kyung Song, Tae Joo Park, Moonil Kim, Sebyung Kang, Yoonji Bae
Publikováno v:
Chemical communications (Cambridge, England). 51(54)
A recombinant target-specific signal amplifier was constructed by genetically fusing the enhanced ascorbate peroxidase 2 (APEX2) and an antibody-binding domain (ABD). The fusion protein APEX2–ABD possessed the peroxidase activity and the antibody-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c91c964e41944cc084c4741dd66db4c
https://pubmed.ncbi.nlm.nih.gov/26063640
https://pubmed.ncbi.nlm.nih.gov/26063640
Publikováno v:
Biomacromolecules. 14(7)
P22 viral capsids and ferritin protein cages are utilized as templating macromolecules to conjugate Gd(III)-chelating agent complexes, and we systematically investigates the effects of the macromolecules' size and the conjugation positions of Gd(III)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4129dcc3aa6df913e63e493b12d316
https://pubmed.ncbi.nlm.nih.gov/23758486
https://pubmed.ncbi.nlm.nih.gov/23758486