Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Junpei Kobayashi"'
Autor:
Tetsuya Akaishi, Junpei Kobayashi, Michiaki Abe, Kota Ishizawa, Ichiro Nakashima, Masashi Aoki, Tadashi Ishii
Publikováno v:
Journal of General and Family Medicine, Vol 20, Iss 5, Pp 193-198 (2019)
Abstract Background Several types of physical examinations are used in the diagnosis of meningitis, including nuchal rigidity, jolt accentuation, Kernig's sign, and Brudzinski's sign. Jolt accentuation was reported to have sensitivity of nearly 100%
Externí odkaz:
https://doaj.org/article/470904cb0f98468089596bd54a66984e
Autor:
Michinori Ezura, Akio Kikuchi, Nobuyuki Okamura, Aiko Ishiki, Takafumi Hasegawa, Ryuichi Harada, Shoichi Watanuki, Yoshihito Funaki, Kotaro Hiraoka, Toru Baba, Naoto Sugeno, Shun Yoshida, Junpei Kobayashi, Michiko Kobayashi, Ohito Tano, Shun Ishiyama, Takaaki Nakamura, Ichiro Nakashima, Shunji Mugikura, Ren Iwata, Yasuyuki Taki, Katsutoshi Furukawa, Hiroyuki Arai, Shozo Furumoto, Manabu Tashiro, Kazuhiko Yanai, Yukitsuka Kudo, Atsushi Takeda, Masashi Aoki
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Introduction: We aimed to determine whether in vivo tau deposits and monoamine oxidase B (MAO-B) detection using 18F-THK5351 positron emission tomography (PET) can assist in the differential distribution in patients with corticobasal syndrome (CBS),
Externí odkaz:
https://doaj.org/article/32c907a418364c868797fbcc1c7cd9a0
Autor:
Aya Inoue-Shibui, Masaaki Kato, Naoki Suzuki, Junpei Kobayashi, Yoshiki Takai, Rumiko Izumi, Yuuko Kawauchi, Hiroshi Kuroda, Hitoshi Warita, Masashi Aoki
Publikováno v:
BMC Neurology, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Riluzole is the only approved oral drug for amyotrophic lateral sclerosis (ALS). We performed a retrospective study including ALS patients treated with riluzole, focusing on adverse events. Methods Patients diagnosed with ALS acco
Externí odkaz:
https://doaj.org/article/f11da1a81b5a49ce96233869edac9bd4
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2018)
Parkinson's disease (PD) is the second most common devastating neurodegenerative disorder after Alzheimer's disease. The precise molecular and cellular basis underlying PD still remains uncertain; however, accumulating evidence suggests that neuronal
Externí odkaz:
https://doaj.org/article/b309dca39b5045a0bfad050c1ec396f0
Autor:
Aiko Ishiki, Michinori Ezura, Takafumi Hasegawa, Shunji Mugikura, Manabu Tashiro, Yasuyuki Taki, Michiko Kobayashi, Ren Iwata, Yoshihito Funaki, Akio Kikuchi, Ryuichi Harada, Shun Yoshida, Ryuji Oshima, Hiroyuki Arai, Shoichi Watanuki, Kotaro Hiraoka, Shozo Furumoto, Toru Baba, Ohito Tano, Junpei Kobayashi, Katsutoshi Furukawa, Kazuhiko Yanai, Nobuyuki Okamura, Masashi Aoki, Atsushi Takeda, Naoto Sugeno, Yukitsuka Kudo, Ichiro Nakashima
Publikováno v:
European Journal of Neurology. 26:1205-1211
Background and purpose Corticobasal syndrome (CBS) is pathologically characterized by tau deposits in neuronal and glial cells and by reactive astrogliosis. In several neurodegenerative disorders, 18 F-THK5351 has been observed to bind to reactive as
Publikováno v:
Brain and nerve = Shinkei kenkyu no shinpo. 72(2)
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease. Although the standard dopamine replacement therapy can alleviate motor symptoms, presently there is no available treatment to stop or reverse dise
Autor:
Kiyotoshi Sekiguchi, Michinori Ezura, Naoto Sugeno, Akemi Ido-Fujibayashi, Mitsunori Fukuda, Mari Suzuki, Takafumi Hasegawa, Masashi Aoki, Toru Baba, Atsushi Takeda, Yoshitaka Nagai, Morio Ueyama, Akio Kikuchi, Junpei Kobayashi, Hideki Mochizuki, Shun Yoshida
Publikováno v:
Human Molecular Genetics. 27:823-836
Mutations in DNAJC13 gene have been linked to familial form of Parkinson's disease (PD) with Lewy pathology. DNAJC13 is an endosome-related protein and believed to regulate endosomal membrane trafficking. However, the mechanistic link between DNAJC13
Autor:
Jun Higuchi, Takaaki Nakamura, Ryuhei Harada, Junpei Kobayashi, Masaki Ogura, Kaoru Endo, Hiroshi Komamura
Publikováno v:
Journal of Infection and Chemotherapy. 25:362-364
Early neurosyphilis commonly appears in basilar meninges, and its meningeal inflammation can spread to neighboring cranial nerves, resulting in some cranial nerve palsies. Herein, we report a case of a 51-year-old man who presented with right periphe
Autor:
David, Seiffge, Gian Marco De Marchis, Masatoshi, Koga, Maurizio, Paciaroni, Duncan, Wilson, Manuel, Cappellari, Kosmas, Macha, Georgios, Tsivgoulis, Gareth, Ambler, Shoji, Arihiro, Leo, H Bonati, Bruno, Bonetti, Bernd, Kallmünzer, Keith, W Muir, Paolo, Bovi, Henrik, Gensicke, Manabu, Inoue, Stefan, Schwab, Shadi, Yaghi, Martin, M Brown, Philippe, Lyrer, Masahito, Takagi, Monica, Acciarrese, Hans Rolf Jager, Alexandros, A Polymeris, Kazunori, Toyoda, Michele, Venti, Christopher, Traenka, Hiroshi, Yamagami, Andrea, Alberti, Sohei, Yoshimura, Valeria, Caso, Stefan, T Engelter, David, J Werring, Kenichi, Todo, Kazumi, Kimura, Kensaku, Shibazaki, Yoshiki, Yagita, Eisuke, Furui, Ryo, Itabashi, Tadashi, Terasaki, Yoshiaki, Shiokawa, Teruyuki, Hirano, Rieko, Suzuki, Kenji, Kamiyama, Jyoji, Nakagawara, Shunya, Takizawa, Kazunari, Homma, Satoshi, Okuda, Yasushi, Okada, Koichiro, Maeda, Tomoaki, Kameda, Kazuomi, Kario, Yoshinari, Nagakane, Yasuhiro, Hasegawa, Hisanao, Akiyama, Satoshi, Shibuya, Hiroshi, Mochizuki, Yasuhiro, Ito, Takahiro, Nakashima, Hideki, Matsuoka, Kazuhiro, Takamatsu, Kazutoshi, Nishiyama, Kanta, Tanaka, Kaoru, Endo, Tetsuya, Miyagi, Masato, Osaki, Junpei, Kobayashi, Takuya, Okata, Eijiro, Tanaka, Yuki, Sakamoto, Keisuke, Tokunaga, Hotake, Takizawa, Junji, Takasugi, Soichiro, Matsubara, Kyoko, Higashida, Takayuki, Matsuki, Naoto, Kinoshita, Masayuki, Shiozawa, Toshihiro, Ide, Takeshi, Yoshimoto, Daisuke, Ando, Kyohei, Fujita, Masaya, Kumamoto, Teppei, Kamimura, Muneaki, Kikuno, Tadataka, Mizoguchi, Takeo, Sato, Karen, L Furie, Prasanna, Tadi, Cecilia, Becattini, Nicola, Falocci, Marialuisa, Zedde, Azmil, H Abdul-Rahim, Kennedy, R Lees, Cataldo, D’Amore, Maria, G Mosconi, Ludovica, A Cimini, Monica, Carletti, Alberto, Rigatelli, Jukka, Putaala, Liisa, Tomppo, Turgut, Tatlisumak, Fabio, Bandini, Simona, Marcheselli, Alessandro, Pezzini, Loris, Poli, Alessandro, Padovani, Luca, Masotti, Vieri, Vannucchi, Sung-Il, Sohn, Gianni, Lorenzini, Rossana, Tassi, Francesca, Guideri, Maurizio, Acampa, Giuseppe, Martini, George, Ntaios, Efstathia, Karagkiozi, George, Athanasakis, Kostantinos, Makaritsis, Kostantinos, Vadikolias, Chrysoula, Liantinioti, Maria, Chondrogianni, Nicola, Mumoli, Domenico, Consoli, Franco, Galati, Simona, Sacco, Antonio, Carolei, Cindy, Tiseo, Francesco, Corea, Walter, Ageno, Marta, Bellesini, Giorgio, Silvestrelli, Alfonso, Ciccone, Umberto, Scoditti, Licia, Denti, Mancuso, Michelangelo, Miriam, Maccarrone, Orlandi, Giovanni, Nicola, Giannini, Gino, Gialdini, Tiziana, Tassinari, Maria Luisa De Lodovici, Giorgio, Bono, Christina, Rueckert, Antonio, Baldi, Danilo, Toni, Federica, Letteri, Martina, Giuntini, Enrico, M Lotti, Yuriy, Flomin, Alessio, Pieroni, Odysseas, Kargiotis, Theodore, Karapanayiotides, Serena, Monaco, Laszló, Csiba, Lilla, Szabó, Alberto, Chiti, Elisa, Giorli, Massimo Del Sette, Davide, Imberti, Dorjan, Zabzuni, Boris, Doronin, Vera, Volodina, Patrik, Michel, Peter, Vanacker, Kristian, Barlinn, Lars, P Pallesen, Ulf, Bodechtel, Leonardo, Ulivi, Dirk, Deleu, Gayane, Melikyan, Jessica, Bourlinn, Naveed, Akhar, Falsal, Ibrahin, Gourbali, Vanessa, Hawone, Baronello, Lisa, Hert, Nils, Peters, Marina, Maurer, Martina, Wiegert
Publikováno v:
Annals of Neurology
Seiffge, David J.; De Marchis, Gian Marco; Koga, Masatoshi; Paciaroni, Maurizio; Wilson, Duncan; Cappellari, Manuel; Macha Md, Kosmas; Tsivgoulis, Georgios; Ambler, Gareth; Arihiro, Shoji; Bonati, Leo H; Bonetti, Bruno; Kallmünzer, Bernd; Muir, Keith W; Bovi, Paolo; Gensicke, Henrik; Inoue, Manabu; Schwab, Stefan; Yaghi, Shadi; Brown, Martin M; ... (2020). Ischemic Stroke despite Oral Anticoagulant Therapy in Patients with Atrial Fibrillation. (In Press). Annals of neurology, 87(5), pp. 677-687. Wiley-Blackwell 10.1002/ana.25700
Seiffge, David J.; De Marchis, Gian Marco; Koga, Masatoshi; Paciaroni, Maurizio; Wilson, Duncan; Cappellari, Manuel; Macha Md, Kosmas; Tsivgoulis, Georgios; Ambler, Gareth; Arihiro, Shoji; Bonati, Leo H; Bonetti, Bruno; Kallmünzer, Bernd; Muir, Keith W; Bovi, Paolo; Gensicke, Henrik; Inoue, Manabu; Schwab, Stefan; Yaghi, Shadi; Brown, Martin M; ... (2020). Ischemic Stroke despite Oral Anticoagulant Therapy in Patients with Atrial Fibrillation. (In Press). Annals of neurology, 87(5), pp. 677-687. Wiley-Blackwell 10.1002/ana.25700
Objective:\ud It is not known whether patients with atrial fibrillation (AF) with ischemic stroke despite oral anticoagulant therapy are at increased risk for further recurrent strokes or how ongoing secondary prevention should be managed.\ud \ud Met
Autor:
Masashi Aoki, Yasuo Miki, Naoto Sugeno, Koichi Wakabayashi, Shun Yoshida, Koki Fujimori, Tetsuya Akiyama, Yasushi Kawata, Michinori Ezura, Mitsunori Fukuda, Atsushi Takeda, Junpei Kobayashi, Arata Tomiyama, Makoto Kanzaki, Toru Baba, Hiroyasu Hatakeyama, Hideyuki Okano, Takafumi Hasegawa, Tohru Yamakuni, Akio Kikuchi, Ichiro Kawahata
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(9)
The neuropathological hallmarks of Parkinson's disease (PD) include the appearance of α-synuclein (α-SYN)-positive Lewy bodies (LBs) and the loss of catecholaminergic neurons. Thus, a potential mechanism promoting the uptake of extracellular α-SYN