Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Junnam, Lee"'
Autor:
Mingyun Bae, Gyuhee Kim, Tae-Rim Lee, Jin Mo Ahn, Hyunwook Park, Sook Ryun Park, Ki Byung Song, Eunsung Jun, Dongryul Oh, Jeong-Won Lee, Young Sik Park, Ki-Won Song, Jeong-Sik Byeon, Bo Hyun Kim, Joo Hyuk Sohn, Min Hwan Kim, Gun Min Kim, Eui Kyu Chie, Hyun-Cheol Kang, Sun-Young Kong, Sang Myung Woo, Jeong Eon Lee, Jai Min Ryu, Junnam Lee, Dasom Kim, Chang-Seok Ki, Eun-Hae Cho, Jung Kyoon Choi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Multi-cancer early detection remains a key challenge in cell-free DNA (cfDNA)-based liquid biopsy. Here, we perform cfDNA whole-genome sequencing to generate two test datasets covering 2125 patient samples of 9 cancer types and 1241 normal c
Externí odkaz:
https://doaj.org/article/df10ed343d5c4d9d913691c7935c3617
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
With advances in next-generation sequencing technology, non-invasive prenatal testing (NIPT) has been widely implemented to detect fetal aneuploidies, including trisomy 21, 18, and 13 (T21, T18, and T13). Most NIPT methods use cell-free DNA (cfDNA) f
Externí odkaz:
https://doaj.org/article/510ecafb3bb64e9292024d86c2119183
Autor:
Jiwoong Yu, Eunhae Cho, Joongwon Choi, Joung Eun Lim, Junnam Lee, Minyong Kang, Hyun Hwan Sung, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Hwang Gyun Jeon
Publikováno v:
Investigative and Clinical Urology, Vol 62, Iss 2, Pp 224-232 (2021)
Purpose: To investigate germline and somatic mutation profiles in Korean patients with prostate cancer using liquid biopsy and solid tissue testing and to evaluate the prognostic value of circulating tumor DNA (ctDNA) in predicting castration resista
Externí odkaz:
https://doaj.org/article/6045e84899b44ecdab745f0eac72a2d6
Autor:
Won Kyung Cho1, Junnam Lee2, Sung-Min Youn, Dongryul Oh1, Do Hoon Lim1, Han Gyul Yoon1,3, Eun-Hae Cho2 ehcho@gccorp.com, Jae Myoung Noh1 jm2.noh@samsung.com
Publikováno v:
Radiation Oncology Journal. Mar2023, Vol. 41 Issue 1, p32-39. 8p.
Autor:
Minyong Kang, Eunhae Cho, Jahyun Jang, Junnam Lee, Youngjoo Jeon, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Hwang Gyun Jeon
Publikováno v:
Investigative and Clinical Urology, Vol 60, Iss 4, Pp 227-234 (2019)
Purpose: To analyze the characteristics of somatic mutations and copy number alterations (CNAs) in Korean patients with advanced prostate cancer (PCa) by use of the Oncomine Comprehensive Panel (ThermoFisher Scientific) and low-coverage, whole-genome
Externí odkaz:
https://doaj.org/article/926e7734cf14406db79e65382adabaa2
Autor:
Chung Ryul Oh, Sun-Young Kong, Hyeon-Su Im, Hwa Jung Kim, Min Kyeong Kim, Kyong-Ah Yoon, Eun-Hae Cho, Ja-Hyun Jang, Junnam Lee, Jihoon Kang, Sook Ryun Park, Baek-Yeol Ryoo
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Although sorafenib is the global standard first-line systemic treatment for unresectable hepatocellular carcinoma (HCC), it does not have reliable predictive or prognostic biomarkers. Circulating cell-free DNA (cfDNA) has shown pr
Externí odkaz:
https://doaj.org/article/d4b0634ea94245ef911858c5c705d2ab
Autor:
Chung Un, Lee, Eunhae, Cho, Junnam, Lee, Joung Eun, Lim, Jae Hoon, Chung, Wan, Song, Minyong, Kang, Hyun Hwan, Sung, Byong Chang, Jeong, Seong Il, Seo, Seong Soo, Jeon, Hyun Moo, Lee, Hwang Gyun, Jeon
Publikováno v:
European Urology Focus. 9:89-95
Although patients with metastatic hormone-sensitive prostate cancer (mHSPC) undergo androgen deprivation therapy (ADT), the disease can progress to metastatic castration-resistant prostate cancer (mCRPC). There are no reliable biomarkers for predicti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92fc4d9cad29353b2430181507d6a43c
https://doi.org/10.1016/j.euf.2022.09.002
https://doi.org/10.1016/j.euf.2022.09.002
Autor:
Seong Eun Bak, Hanwool Kim, Jung Yoon Ho, Eun-Hae Cho, Junnam Lee, Sung Min Youn, Seong-Woo Park, Mi-Ryung Han, Soo Young Hur, Sung Jong Lee, Youn Jin Choi
Publikováno v:
Cancers; Volume 15; Issue 2; Pages: 530
Despite the progress in diagnostics and therapeutics, epithelial ovarian cancer (EOC) remains a fatal disease. Using shallow whole-genome sequencing of plasma cell-free DNA (cfDNA), we investigated biomarkers that could detect EOC and predict surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3b182474a7e4983d0187a8001911e9
Publikováno v:
Genomics & Informatics, Vol 10, Iss 4, Pp 234-238 (2012)
Genetic epidemiology studies have established that the natural variation of gene expression profiles is heritable and has genetic bases. A number of proximal and remote DNA variations, known as expression quantitative trait loci (eQTLs), that are ass
Externí odkaz:
https://doaj.org/article/aeba1a1e8c364d66b6e8e6eb6aa9a6af
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 45:1925-1928
Maternal copy number variation (CNV), especially at the X chromosome is an important cause of false positive noninvasive prenatal test (NIPT) results for sex chromosomal aneuploidy. In addition, some maternal CNV can cause significant anomalies if th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e4795870ba0249af122074d1a48050d
https://doi.org/10.1111/jog.14033
https://doi.org/10.1111/jog.14033