Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Junmin Fu"'
Autor:
Shuai Shao, Huan Xia, Min Hu, Chengjuan Chen, Junmin Fu, Gaona Shi, Qinglan Guo, Yu Zhou, Wenjie Wang, Jiangong Shi, Tiantai Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-11 (2020)
Abstract Background Isotalatizidine is a representative C19-diterpenoid alkaloid extracted from the lateral roots of Aconitum carmichaelii, which has been widely used to treat various diseases on account of its analgesic, anti-inflammatory, anti-rheu
Externí odkaz:
https://doaj.org/article/2796c883d6434012a29172576a513aae
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Dendritic cells (DCs) are antigen-presenting cells that play a pivotal role in adaptive cell-mediated immunity by priming and activating T cells against specific tumour and pathogenic antigens. Methotrexate (MTX), a folate derivative, fun
Externí odkaz:
https://doaj.org/article/ebd509183ad54ec5bc144479e05b19ba
Autor:
Jinze Li, Xiaowei Ma, Yu Wang, Chengjuan Chen, Min Hu, Linlin Wang, Junmin Fu, Gaona Shi, Dongming Zhang, Tiantai Zhang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Neuroinflammatory reactions mediated by microglia and astrocytes have been shown to play a key role in early progression of Alzheimer’s disease (AD). Increased evidences have demonstrated that neurons exacerbate local inflammatory reactions by prod
Externí odkaz:
https://doaj.org/article/eb1a668134af417e8f4bc33f3e178c08
Publikováno v:
Oncology Reports. 50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d84b9c7610f12e089a0f6e80fddd844d
https://doi.org/10.3892/or.2023.8573
https://doi.org/10.3892/or.2023.8573
Autor:
Yu Zhou, Tiantai Zhang, Gaona Shi, Shuai Shao, Xinpeng Li, Chengjuan Chen, Junmin Fu, Min Hu, Dan Zhang, Song Wu, Dongmei Wang
Publikováno v:
European Journal of Medicinal Chemistry. 168:207-220
A series of novel isoflavone analogs were designed, synthesized, and evaluated as multitarget-directed ligands for the treatment of Alzheimer's disease. In vitro evaluations revealed that some ligands had multifunctional profiles, including potent bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad70c04d3c2e8aecf3cc64cd8187cc3
https://doi.org/10.1016/j.ejmech.2019.02.053
https://doi.org/10.1016/j.ejmech.2019.02.053
Autor:
Yingda Zang, Shuai Shao, Gaona Shi, Dong-Ming Zhang, Tao Sun, Tiantai Zhang, Yu Zhou, Chengjuan Chen, Junmin Fu, Lei Wu, Guoyuan Zhu
Publikováno v:
International immunopharmacology. 94
Inflammatory bowel disease (IBD) is generally characterized by chronic inflammatory disorders of the gastrointestinal tract that are known as ulcerative colitis (UC) or Crohn's disease (CD). Although the underlying mechanism of action of IBD is uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3880dc133a11f8192092d5bd9fe00c9a
https://pubmed.ncbi.nlm.nih.gov/33611058
https://pubmed.ncbi.nlm.nih.gov/33611058
Publikováno v:
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Dendritic cells (DCs) are antigen-presenting cells that play a pivotal role in adaptive cell-mediated immunity by priming and activating T cells against specific tumour and pathogenic antigens. Methotrexate (MTX), a folate derivative, fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04bd48f180982c80318696830835bc2
https://pubmed.ncbi.nlm.nih.gov/33613696
https://pubmed.ncbi.nlm.nih.gov/33613696
Autor:
Junmin Fu, Chengjuan Chen, Gaona Shi, Min Hu, Yu Zhou, Yingda Zang, Lei Wu, Shuai Shao, Tiantai Zhang, Dong-Ming Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 126, Iss, Pp 110084-(2020)
Sepsis is a main reason for death in intensive care units, inflammation is closely related to sepsis. Anti-inflammation plays an important role in treating of sepsis. ZT01 is a triptolide derivative with strong anti-inflammatory activity and low toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9297ad76e184077d39efc07e25692b12
https://pubmed.ncbi.nlm.nih.gov/32171166
https://pubmed.ncbi.nlm.nih.gov/32171166
Autor:
Ke Liu, Chengjuan Chen, Tiantai Zhang, Dong-Ming Zhang, Fangfang Lai, Yingda Zang, Junmin Fu, Chuang-Jun Li, Jie Ma, Xiaoguang Chen
Publikováno v:
European journal of medicinal chemistry. 190
A series of novel triptolide/furoxans hybrids were designed and synthesized as analogues of triptolide, which is a naturally derived compound isolated from the thunder god vine (Tripterygium wilfordii Hook. F). Some of these synthesized compounds exh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405047dec9fbc6723b1b52816823f19b
https://pubmed.ncbi.nlm.nih.gov/32028140
https://pubmed.ncbi.nlm.nih.gov/32028140
Autor:
Shuai, Shao, Huan, Xia, Min, Hu, Chengjuan, Chen, Junmin, Fu, Gaona, Shi, Qinglan, Guo, Yu, Zhou, Wenjie, Wang, Jiangong, Shi, Tiantai, Zhang
Publikováno v:
Journal of Neuroinflammation
Background Isotalatizidine is a representative C19-diterpenoid alkaloid extracted from the lateral roots of Aconitum carmichaelii, which has been widely used to treat various diseases on account of its analgesic, anti-inflammatory, anti-rheumatic, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24375da01e8536781da665baa1a71c55
https://pubmed.ncbi.nlm.nih.gov/31924228
https://pubmed.ncbi.nlm.nih.gov/31924228