Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Junli, Gao"'
Autor:
Jing Sun, Yue Liu, Jianhui Zhao, Bin Lu, Siyun Zhou, Wei Lu, Jingsun Wei, Yeting Hu, Xiangxing Kong, Junshun Gao, Hong Guan, Junli Gao, Qian Xiao, Xue Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract This study aims to identify colorectal cancer (CRC)-related proteomic profiles and develop a prediction model for CRC onset by integrating proteomic profiles with genetic and non-genetic factors (QCancer-15) to improve the risk stratificatio
Externí odkaz:
https://doaj.org/article/1ff44e3713264dcb98354913a85c38c4
Autor:
Yang Che, Yewei Lu, Yelei Zhu, Tianfeng He, Xiangchen Li, Junli Gao, Junshun Gao, Xiaomeng Wang, Zhengwei Liu, Feng Tong
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundLeveraging well-established DNA-level drug resistance mechanisms, whole-genome sequencing (WGS) has emerged as a valuable methodology for predicting drug resistance. As the most effective second-line anti-tuberculosis (anti-TB) drugs, fluor
Externí odkaz:
https://doaj.org/article/b9c7677c302d43b2a1e6e8189a223752
Autor:
Yuhao Min, Xue Wang, Özkan İş, Tulsi A. Patel, Junli Gao, Joseph S. Reddy, Zachary S. Quicksall, Thuy Nguyen, Shu Lin, Frederick Q. Tutor-New, Jessica L. Chalk, Adriana O. Mitchell, Julia E. Crook, Peter T. Nelson, Linda J. Van Eldik, Todd E. Golde, Minerva M. Carrasquillo, Dennis W. Dickson, Ke Zhang, Mariet Allen, Nilüfer Ertekin-Taner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Progressive supranuclear palsy (PSP) is a neurodegenerative parkinsonian disorder characterized by cell-type-specific tau lesions in neurons and glia. Prior work uncovered transcriptome changes in human PSP brains, although their cell-specif
Externí odkaz:
https://doaj.org/article/7eb936ba3b1b4dcfaae93bda5909f002
Autor:
Yang Che, Xiangchen Li, Tong Chen, Yewei Lu, Guoxin Sang, Junli Gao, Junshun Gao, Zhengwei Liu, Tianfeng He, Yi Chen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundTuberculosis (TB), particularly drug-resistant TB (DR-TB), remains a significant public health concern in Ningbo, China. Understanding its molecular epidemiology and spatial distribution is paramount for effective control.MethodsFrom Decemb
Externí odkaz:
https://doaj.org/article/a053685d08b74f099f0eeeaa50ae3f45
Publikováno v:
PLoS ONE, Vol 19, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/26e00a1b01064d9ab7a0ed9a4aff3e1d
Autor:
Bilal Khalil, Deepak Chhangani, Melissa C. Wren, Courtney L. Smith, Jannifer H. Lee, Xingli Li, Christian Puttinger, Chih-Wei Tsai, Gael Fortin, Dmytro Morderer, Junli Gao, Feilin Liu, Chun Kim Lim, Jingjiao Chen, Ching-Chieh Chou, Cara L. Croft, Amanda M. Gleixner, Christopher J. Donnelly, Todd E. Golde, Leonard Petrucelli, Björn Oskarsson, Dennis W. Dickson, Ke Zhang, James Shorter, Shige H. Yoshimura, Sami J. Barmada, Diego E. Rincon-Limas, Wilfried Rossoll
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-27 (2022)
Abstract Background Cytoplasmic mislocalization and aggregation of TAR DNA-binding protein-43 (TDP-43) is a hallmark of the amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD) disease spectrum, causing both nuclear loss-of-function an
Externí odkaz:
https://doaj.org/article/bbd064334e3c44abbee70cb5d84f3100
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Colorectal cancer (CRC) is one of the most significant neoplasms with high morbidity and mortality. Activation of the programmed death protein 1/programmed death ligand 1 (PD-1/PD-L1) signaling pathway results in tumor immune evasion by suppressing t
Externí odkaz:
https://doaj.org/article/058dda2dc1d84cc29beb11de9a475c94
Autor:
Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease with ill-defined pathogenesis, calling for urgent developments of new therapeutic regimens. Herein, we applied PandaOmics, an AI-driven target discovery platform, to analyze th
Externí odkaz:
https://doaj.org/article/d12999749a99465fb2c046587d7bb7ef
Autor:
Junli Gao, Jiajun Wang
Publikováno v:
Applied Sciences, Vol 13, Iss 11, p 6614 (2023)
The interfacial friction performance of the liner system has an important influence on the overall stability of modern landfills, but the interface of the liner system using conventional geomembranes may have problems such as shear failure and slip a
Externí odkaz:
https://doaj.org/article/122b80f0b62841f681b6b4ce32167f29
Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD
Autor:
Xiaoqiang Tang, Arturo Toro, Sahana T.G., Junli Gao, Jessica Chalk, Björn E. Oskarsson, Ke Zhang
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-15 (2020)
Abstract Ever since a GGGGCC hexanucleotide repeat expansion mutation in C9ORF72 was identified as the most common cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), three competing but nonexclusive hypotheses to
Externí odkaz:
https://doaj.org/article/631998beccdd4479af9a1d5ea3d330c1