Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Junko Zenkoh"'
Autor:
Yasuhiko Haga, Yoshitaka Sakamoto, Keiko Kajiya, Hitomi Kawai, Miho Oka, Noriko Motoi, Masayuki Shirasawa, Masaya Yotsukura, Shun-Ichi Watanabe, Miyuki Arai, Junko Zenkoh, Kouya Shiraishi, Masahide Seki, Akinori Kanai, Yuichi Shiraishi, Yasushi Yatabe, Daisuke Matsubara, Yutaka Suzuki, Masayuki Noguchi, Takashi Kohno, Ayako Suzuki
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The mechanism underlying the development of tumors, particularly at early stages, still remains mostly elusive. Here, we report whole-genome long and short read sequencing analysis of 76 lung cancers, focusing on very early-stage lung adenoc
Externí odkaz:
https://doaj.org/article/04dd43d62a6b41fea8001fa49282ad6a
Autor:
Yuki Ozato, Yasuhiro Kojima, Yuta Kobayashi, Yuuichi Hisamatsu, Takeo Toshima, Yusuke Yonemura, Takaaki Masuda, Kouichi Kagawa, Yasuhiro Goto, Mitsuaki Utou, Mituko Fukunaga, Ayako Gamachi, Kiyomi Imamura, Yuta Kuze, Junko Zenkoh, Ayako Suzuki, Atsushi Niida, Haruka Hirose, Shuto Hayashi, Jun Koseki, Eiji Oki, Satoshi Fukuchi, Kazunari Murakami, Taro Tobo, Satoshi Nagayama, Mamoru Uemura, Takeharu Sakamoto, Masanobu Oshima, Yuichiro Doki, Hidetoshi Eguchi, Masaki Mori, Takeshi Iwasaki, Yoshinao Oda, Tatsuhiro Shibata, Yutaka Suzuki, Teppei Shimamura, Koshi Mimori
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111929- (2023)
Summary: The cellular interactions in the tumor microenvironment of colorectal cancer (CRC) are poorly understood, hindering patient treatment. In the current study, we investigate whether events occurring at the invasion front are of particular impo
Externí odkaz:
https://doaj.org/article/36523fb8ccbc455a9c49d7317c9ee01e
Autor:
Naoki Onoda, Ayako Kawabata, Kumi Hasegawa, Megumi Sakakura, Itaru Urakawa, Masahide Seki, Junko Zenkoh, Ayako Suzuki, Yutaka Suzuki
Publikováno v:
DNA research : an international journal for rapid publication of reports on genes and genomes. 29(2)
The kidney is a complex organ that consists of various types of cells. It is occasionally difficult to resolve molecular alterations and possible perturbations that the kidney experiences due to drug-induced damage. In this study, we performed spatia
Autor:
Keiichi Onodera, Junko Zenkoh, Hitomi Okazaki, Shoko Nakasone, Genichiro Ishii, Ayako Suzuki, Yutaka Suzuki, Masahiro Tsuboi, Katsuya Tsuchihara
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 158
Objectives Microtubule inhibitors (MTIs) are widely used as anti-cancer drugs for various types of tumors. Vinorelbine, an MTI, is utilized in postoperative adjuvant chemotherapy, especially for lung adenocarcinoma. However, no molecular markers are
Autor:
Ariungerel Gerelchuluun, Junko Zenkoh, Xiao-Kang Li, Koji Tsuboi, Lue Sun, Songjie Cai, Yuzi Wang
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 103:958-969
Purpose Danger signals and release of tumor-specific antigens after exposure to ionizing radiation can convert an irradiated tumor into an in situ vaccine. However, radiation alone is not sufficient to induce an effective systemic immune response. In
Publikováno v:
Translational Cancer Research. 6(1):136-148
Background: Localized radiotherapy is considered to act as an adjuvant for systemic anti-tumor immunity. We examined whether in situ-irradiated peripheral tumor cells can evoke an abscopal effect in the brain inhibiting malignant tumor growth. Method
Autor:
Koji Tsuboi, Ariungerel Gerelchuluun, Kenshi Suzuki, Zhengshan Hong, Biao Le, Takashi Moritake, Junji Urakawa, Masakazu Washio, Junko Zenkoh
Publikováno v:
Journal of Radiation Research
We generated low-flux X-ray micro-planar beams (MPBs) using a laboratory-scale industrial X-ray generator (60 kV/20 mA) with custom-made collimators with three different peak/pitch widths (50/200 μm, 100/400 μm, 50/400 μm). To evaluate normal skin
Autor:
Junko Zenkoh, Yun-Wen Zheng, Koji Tsuboi, Lue Sun, Kenshi Suzuki, Takashi Moritake, Zhengshan Hong, Hideki Taniguchi, Ariungerel Gerelchuluun
Publikováno v:
Journal of Radiation Research
One-third of patients with medulloblastoma die due to recurrence after various treatments including radiotherapy. Although it has been postulated that cancer stem-like cells are radio-resistant and play an important role in tumor recurrence, the "ste
Autor:
Shigeki Satoh, Hiroe Sawai, Hitoshi Kojo, Noriyuki Morikawa, Teruo Oku, Yoshitada Notsu, Tsuyoshi Mizutani, Noriaki Inamura, Ichiro Aramori, Yuki Sawada, Chie Hatori, Yoshito Abe, Hiroshi Kayakiri, Takayuki Inoue, Masayuki Asano, Junko Zenkoh, Kunio Nakahara
Publikováno v:
Molecular Pharmacology. 52:16-20
Kinins, members of a family of peptides released from kininogens by the action of kallikreins, exhibit a variety of biological activities including vasodilation, increased vascular permeability, contraction of smooth muscle cells, and activation of s
Autor:
Hitoshi Kojo, Junko Zenkoh, Ichiro Aramori, Morita Iwami, Kozo Nakamura, Masayuki Asano, Noriyuki Morikawa, Nuala O’Donnell, Yoshitada Notsu
Publikováno v:
Molecular Pharmacology. 51:171-176
We describe the receptor binding and antagonistic properties of two novel nonpeptide antagonists, FR167344 (3-bromo-8-[2,6-dichloro-3-[ N -[( E )-4-( N , N -dimethylcarbamoyl)cinnamidoacetyl]- N -methylamino]benzyloxy]-2-methylimidazo[1,2-a]pyridine