Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Junko TOMIKAWA"'
Autor:
Junko Tomikawa
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Mammalian genomic DNA is packed in a small nucleus, and its folding and organization in the nucleus are critical for gene regulation and cell fate determination. In interphase, chromosomes are compartmentalized into certain nuclear spaces and territo
Externí odkaz:
https://doaj.org/article/147aa10e138d48e9982aaedf156a3c49
Autor:
Kyoko Oshina, Keiji Kuroda, Kazuhiko Nakabayashi, Junko Tomikawa, Mari Kitade, Rikikazu Sugiyama, Kenichiro Hata, Atsuo Itakura
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionChronic endometritis (CE) is a persistent inflammatory condition of the endometrium characterized by the infiltration of plasma cells in the endometrial stroma. CD138 immunohistochemistry is considered to improve the CE diagnosis rate.Met
Externí odkaz:
https://doaj.org/article/897d0dc4c62348f6a8a94ecb322bd6be
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101284- (2022)
Summary: Reprogramming of somatic nuclei toward the embryonic state has been studied using nuclear transfer (NT) to an oocyte at the metaphase II (MII) stage. In this NT, a somatic nucleus transplanted into an MII oocyte of the same species undergoes
Externí odkaz:
https://doaj.org/article/a9cefc5d018644dd95357c4d20c21e38
Autor:
Shiori MINABE, Sho NAKAMURA, Eri FUKUSHIMA, Marimo SATO, Kana IKEGAMI, Teppei GOTO, Makoto SANBO, Masumi HIRABAYASHI, Junko TOMIKAWA, Takuya IMAMURA, Naoko INOUE, Yoshihisa UENOYAMA, Hiroko TSUKAMURA, Kei-Ichiro MAEDA, Fuko MATSUDA
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 4, Pp 369-375 (2020)
Accumulating evidence suggests that kisspeptin-GPR54 signaling is indispensable for gonadotropin-releasing hormone (GnRH)/gonadotropin secretion and consequent reproductive functions in mammals. Conventional Kiss1 knockout (KO) mice and rats are repo
Externí odkaz:
https://doaj.org/article/0e9ff334730b491cb8b0553ce5c4f9ae
Autor:
Kana IKEGAMI, Teppei GOTO, Sho NAKAMURA, Youki WATANABE, Arisa SUGIMOTO, Sutisa MAJARUNE, Kei HORIHATA, Mayuko NAGAE, Junko TOMIKAWA, Takuya IMAMURA, Makoto SANBO, Masumi HIRABAYASHI, Naoko INOUE, Kei-ichiro MAEDA, Hiroko TSUKAMURA, Yoshihisa UENOYAMA
Publikováno v:
The Journal of Reproduction and Development, Vol 66, Iss 4, Pp 359-367 (2020)
The present study aimed to evaluate whether novel conditional kisspeptin neuron-specific Kiss1 knockout (KO) mice utilizing the Cre-loxP system could recapitulate the infertility of global Kiss1 KO models, thereby providing further evidence for the f
Externí odkaz:
https://doaj.org/article/c186e5926f0a4370bf0d6cf650553e0b
Autor:
Junko Tomikawa, Christopher A. Penfold, Takuma Kamiya, Risa Hibino, Ayumi Kosaka, Masayuki Anzai, Kazuya Matsumoto, Kei Miyamoto
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103290- (2021)
Summary: Nuclear transfer systems represent the efficient means to reprogram a cell and in theory provide a basis for investigating the development of endangered species. However, conventional nuclear transfer using oocytes of laboratory animals does
Externí odkaz:
https://doaj.org/article/c7e3d6fbfc5345d496084183d44da4a4
Autor:
Wataru Yoshida, Junko Tomikawa, Makoto Inaki, Hiroshi Kimura, Masafumi Onodera, Kenichiro Hata, Kazuhiko Nakabayashi
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131204 (2015)
Insulators are cis-elements that control the direction of enhancer and silencer activities (enhancer-blocking) and protect genes from silencing by heterochromatinization (barrier activity). Understanding insulators is critical to elucidate gene regul
Externí odkaz:
https://doaj.org/article/ea5206baad9a4a5d86dd6cd5cf4743b8
Autor:
Tomoko Miyata, Kenzo Sonoda, Junko Tomikawa, Chiharu Tayama, Kohji Okamura, Kayoko Maehara, Hiroaki Kobayashi, Norio Wake, Kiyoko Kato, Kenichiro Hata, Kazuhiko Nakabayashi
Publikováno v:
Sarcoma, Vol 2015 (2015)
Uterine leiomyosarcoma (LMS) is the worst malignancy among the gynecologic cancers. Uterine leiomyoma (LM), a benign tumor of myometrial origin, is the most common among women of childbearing age. Because of their similar symptoms, it is difficult to
Externí odkaz:
https://doaj.org/article/9798c746939a4d649e85de4b64438ff4
Autor:
Kei Miyamoto, Junko Tomikawa
Publikováno v:
The FEBS Journal. 289:7221-7233
The regulation of gene expression is a critical process for establishing and maintaining cellular identity. Gene expression is controlled through a chromatin-based mechanism in the nucleus of eukaryotic cells. Recent studies suggest that chromatin ac
Autor:
Yoshihisa Uenoyama, Teppei Goto, Shiori Minabe, Marimo Sato, Naoko Inoue, Takuya Imamura, Kei-ichiro Maeda, Fuko Matsuda, Junko Tomikawa, Makoto Sanbo, Masumi Hirabayashi, Sho Nakamura, Hiroko Tsukamura, Eri Fukushima, Kana Ikegami
Publikováno v:
Journal of Reproduction and Development. 66:369-375
Accumulating evidence suggests that kisspeptin-GPR54 signaling is indispensable for gonadotropin-releasing hormone (GnRH)/gonadotropin secretion and consequent reproductive functions in mammals. Conventional Kiss1 knockout (KO) mice and rats are repo