Výsledky vyhledávání - "Junko Nobuhiro"

Novel synthesis of the 2-azaanthraquinone alkaloid, scorpinone, based on two microwave-assisted pericyclic reactions

Autor: Satoshi Hibino, Junko Nobuhiro, Tominari Choshi, Teppei Kumemura

Publikováno v: Tetrahedron Letters. 49:3725-3728

The total synthesis of the 2-azaanthraquinone alkaloid, scorpinone (4), isolated from the mycelium of a Bispora-like tropical fungus, has been completed in nine steps. The two key steps involve a microwave-assisted thermal electrocyclic reaction for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9473e700b83180173af56e30a241ce82
https://doi.org/10.1016/j.tetlet.2008.04.033

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Synthesis and Anti-tumor Activity of a Fluorinated Analog of Medroxyprogesterone Acetate (MPA), 9.ALPHA.-Fluoromedroxyprogesterone Acetate (FMPA)

Autor: Taketo Yamaji, Tominari Choshi, Satoshi Hibino, Hideo Nemoto, Masashi Yamada, Tsutomu Oikawa, Hiroshi Tsuboi, Yoshitatsu Ichihara, Hiroto Suzuki, Yoshio Sato, Natsuko Murata, Junko Nobuhiro, Shiho Fujimori, Masayuki Uchida

Publikováno v: Chemical and Pharmaceutical Bulletin. 54:1567-1570

We synthesized 9alpha-fluoromedroxyprogesterone acetate (FMPA) in order to test whether it is a more potent anti-angiogenic agent than medroxyprogesterone acetate (MPA), which has been widely used as a therapeutic agent for breast and endometrium can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7908238f09ba6acd68ad95b3567b1d8c
https://doi.org/10.1248/cpb.54.1567

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Synthesis and antimalarial activity of calothrixins A and B, and their N-alkyl derivatives

Autor: Kohji Matsumoto, Tominari Choshi, Mai Hourai, Kenji Sasaki, Minoru Ishikura, Yoshito Zamami, Shigeo Tohyama, Tatsunori Iwamura, Takumi Abe, Noriyuki Hatae, Satoshi Hibino, Junko Nobuhiro

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 22:4762-4764

We synthesized calothrixin B using our developed biomimetic method and derived N-alkyl-calothrixins A and B. The in vitro antimalarial activity of the calothrixin derivatives, including calothrixins A and B, against the Plasmodium falciparum FCR-3 st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362daec544773dd3b529b153ce02e58a
https://doi.org/10.1016/j.bmcl.2012.05.064

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Total Syntheses of β-Carboline Alkaloids, (R)-(−)-Pyridindolol K1, (R)-(−)-Pyridindolol K2, and (R)-(−)-Pyridindolol

Autor: Naoko Kanekiyo, Tominari Choshi, Junko Nobuhiro, Satoshi Hibino, Takeshi Kuwada

Publikováno v: The Journal of Organic Chemistry. 66:8793-8798

The total syntheses of beta-carboline alkaloids, (R)-(-)-pyridindolols (1, 5, and 6) are described. The two key steps involved are (1) a thermal electrocyclic reaction of the 3-alkenylindole-2-aldoxime 10 and (2) a thermal cyclization of 3-alkynylind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf2c0de7c8a175e0a82055aea1a9d6b
https://doi.org/10.1021/jo0105585

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Novel Syntheses of Murrayaquinone A and Furostifoline through 4-Oxygenated Carbazoles by Allene-Mediated Electrocyclic Reactions Starting from 2-Chloroindole-3-carbaldehyde

Autor: Tominari Choshi, Satoshi Hibino, Junko Nobuhiro, Hiroyuki Fujimoto, Hitomi Hagiwara

Publikováno v: Chemical and Pharmaceutical Bulletin. 49:881-886

The formal total synthesis of murrayaquinone A (1) and the total synthesis of furostifoline (5) were completed by the construction of 4-oxygenated 3-methylcarbazoles 7 based on a new type of electrocyclic reaction through 2-alkenyl-3-allenylindole in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa64bc51b7ad64ee3d7440fd4fd8487
https://doi.org/10.1248/cpb.49.881

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A new synthesis of the benzo[c]phenanthridines nornitidine, noravicine, and isodecarine, based on a microwave-assisted electrocyclic reaction of the aza 6π-electron system

Autor: Tominari Choshi, Satoshi Hibino, Junko Nobuhiro, Shuhei Azuma, Kakujiro Kohno

Publikováno v: Tetrahedron Letters. 50:590-592

A new and versatile synthetic route to a benzophenanthridine alkaloid was developed by a bond formation between C4b and N5 on the benzo[c]phenanthridine nucleus, using a microwave-assisted electrocyclic reaction of the aza 6π-electron system. This s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8460f8d7fc4054e254588a54a9e4dfcc
https://doi.org/10.1016/j.tetlet.2008.11.076

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ChemInform Abstract: Novel Syntheses of Murrayaquinone A and Furostifoline Through 4-Oxygenated Carbazoles by Allene-Mediated Electrocyclic Reactions Starting from 2-Chloroindole-3-carbaldehyde

Autor: Hitomi Hagiwara, Hiroyuki Fujimoto, Tominari Choshi, Junko Nobuhiro, Satoshi Hibino

Publikováno v: ChemInform. 32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b973c9e355d0650f41fb459d55a33da8
https://doi.org/10.1002/chin.200152202

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