Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Junko NIO-KOBAYASHI"'
Publikováno v:
Cells, Vol 13, Iss 7, p 612 (2024)
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) featuring numerous neuropathologies, including optic neuritis (ON) in some patients. However, the molecular mechanisms of ON remain unknown. Galectin
Externí odkaz:
https://doaj.org/article/903f36b11c044ca9911064e6e50191d8
Autor:
Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Atsushi Enomoto, Masashi Akiyama, Ryosuke Ichihara, Hisashi Haga
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract The process by which cancer cells invade as a cell cluster, known as collective invasion, is associated with metastasis and worse prognosis of cancer patients; therefore, inhibition of collective invasion is considered to improve cancer trea
Externí odkaz:
https://doaj.org/article/5a3bf3f44d854df0aedbe3b5626f2c03
Autor:
Takaaki Furihata, Shingo Takada, Naoya Kakutani, Satoshi Maekawa, Masaya Tsuda, Junichi Matsumoto, Wataru Mizushima, Arata Fukushima, Takashi Yokota, Nobuyuki Enzan, Shouji Matsushima, Haruka Handa, Yoshizuki Fumoto, Junko Nio-Kobayashi, Toshihiko Iwanaga, Shinya Tanaka, Hiroyuki Tsutsui, Hisataka Sabe, Shintaro Kinugawa
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Takaaki Furihata et al. report a new mouse model with heart-specific deletion of the mitochondrial protein, mitoNEET. Their results suggest that loss of mitoNEET expression may contribute to age-associated heart failure in older adults.
Externí odkaz:
https://doaj.org/article/3f63983eae254d919bb87225d2d4c10c
Autor:
Katarzyna J. Siemienowicz, Yili Wang, Magda Marečková, Junko Nio-Kobayashi, Paul A. Fowler, Mick T. Rae, W. Colin Duncan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Maternal exposure to increased steroid hormones, including estrogens, androgens or glucocorticoids during pregnancy results in chronic conditions in offspring that manifest in adulthood. Little is known about effects of progesterone administ
Externí odkaz:
https://doaj.org/article/f3674f2be6cf4291a7eee02f7f0513c8
Autor:
Junko Nio-Kobayashi, Tetsuya Itabashi
Publikováno v:
Frontiers in Neuroanatomy, Vol 15 (2021)
Galectins are β-galactoside-binding lectins consisting of 15 members in mammals. Galectin-1,-3,-4,-8, and -9 are predominantly expressed in the central nervous system (CNS) and regulate various physiological and pathological events. This review summ
Externí odkaz:
https://doaj.org/article/bdd7f3358cb1405d9c0f0e3565ff8979
Autor:
Zhouoxing Wei, Kenta Shimizu, Rakiiya S. Sarii, Devinda S. Muthusinghe, Sithumini M. W. Lokupathirage, Junko Nio-Kobayashi, Kumiko Yoshimatsu
Publikováno v:
Viruses, Vol 14, Iss 10, p 2247 (2022)
Hantaan virus is the causative agent of hemorrhagic fever with renal syndrome (HFRS). The Hantaan virus strain, Korean hemorrhagic fever virus clone-5 (KHF5), causes weight loss and renal hemorrhage in laboratory mice. Clone-4 (KHF4), which has a sin
Externí odkaz:
https://doaj.org/article/1c21e77ba3904005a99690d2f06f680d
Autor:
Junnosuke Mae, Kazuki Nagaya, Yuko Okamatsu-Ogura, Ayumi Tsubota, Shinya Matsuoka, Junko Nio-Kobayashi, Kazuhiro Kimura
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Brown adipose tissue (BAT) is a specialized tissue that regulates non-shivering thermogenesis. In Syrian hamsters, interscapular adipose tissue is composed primarily of white adipocytes at birth, which is converted to BAT through the proliferation an
Externí odkaz:
https://doaj.org/article/024a792a459e4a75a34371cda9f8c82d
Autor:
Yuko Okamatsu-Ogura, Keigo Fukano, Ayumi Tsubota, Junko Nio-Kobayashi, Kyoko Nakamura, Masami Morimatsu, Hiroshi Sakaue, Masayuki Saito, Kazuhiro Kimura
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract We previously reported brown adipocytes can proliferate even after differentiation. To test the involvement of mature adipocyte proliferation in cell number control in fat tissue, we generated transgenic (Tg) mice over-expressing cell-cycle
Externí odkaz:
https://doaj.org/article/6838be41498147fd85b58353ef6e9288
Autor:
Yasunobu Arima, Takuto Ohki, Naoki Nishikawa, Kotaro Higuchi, Mitsutoshi Ota, Yuki Tanaka, Junko Nio-Kobayashi, Mohamed Elfeky, Ryota Sakai, Yuki Mori, Tadafumi Kawamoto, Andrea Stofkova, Yukihiro Sakashita, Yuji Morimoto, Masaki Kuwatani, Toshihiko Iwanaga, Yoshichika Yoshioka, Naoya Sakamoto, Akihiko Yoshimura, Mitsuyoshi Takiguchi, Saburo Sakoda, Marco Prinz, Daisuke Kamimura, Masaaki Murakami
Publikováno v:
eLife, Vol 6 (2017)
Impact of stress on diseases including gastrointestinal failure is well-known, but molecular mechanism is not understood. Here we show underlying molecular mechanism using EAE mice. Under stress conditions, EAE caused severe gastrointestinal failure
Externí odkaz:
https://doaj.org/article/6445d973bd714f3daf24e52765425cf7
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166579 (2016)
Hyperplasia of brown adipose tissue (BAT) is a fundamental mechanism for adaptation to survive in the cold environment in rodents. To determine which cell types comprising BAT contribute to tissue hyperplasia, immunohistochemical analysis using a pro
Externí odkaz:
https://doaj.org/article/6a8cc593f71c4ad393f3c8666683d721