Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Junko Maruyama"'
Autor:
Jane Chanda Kabwe, Hirofumi Sawada, Yoshihide Mitani, Hironori Oshita, Naoki Tsuboya, Erquan Zhang, Junko Maruyama, Yoshiki Miyasaka, Hideyoshi Ko, Kazunobu Oya, Hiromasa Ito, Noriko Yodoya, Shoichiro Otsuki, Hiroyuki Ohashi, Ryuji Okamoto, Kaoru Dohi, Yuhei Nishimura, Tomoji Mashimo, Masahiro Hirayama, Kazuo Maruyama
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-22 (2022)
Abstract Background Patients with pulmonary arterial hypertension (PAH) carrying bone morphogenetic protein receptor type 2 (Bmpr2) mutations present earlier with severe hemodynamic compromise and have poorer survival outcomes than those without muta
Externí odkaz:
https://doaj.org/article/92a8518c4a4b459c8d7fad7b798a5a72
Autor:
Masako Kawai, Erquan Zhang, Jane Chanda Kabwe, Amphone Okada, Junko Maruyama, Hirofumi Sawada, Kazuo Maruyama
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Rats with chronic hypoxia-induced non-inflammatory pulmonary hypertension (PH) are resistant to ventilator-induced lung injury. We investigated the effect of high tidal volume ventilation in another model of PH, monocrotaline (MCT
Externí odkaz:
https://doaj.org/article/1e537076e92a4f41bb8ab98a649f7107
Autor:
Toshikazu Ito, Erquan Zhang, Ayaka Omori, Jane Kabwe, Masako Kawai, Junko Maruyama, Amphone Okada, Ayumu Yokochi, Hirofumi Sawada, Yoshihide Mitani, Kazuo Maruyama
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background Preventing pulmonary vascular remodeling is a key strategy for pulmonary hypertension (PH). Causes of PH include pulmonary vasoconstriction and inflammation. This study aimed to determine whether cilostazol (CLZ), a phosphodiester
Externí odkaz:
https://doaj.org/article/c584309c6a5d45aaa3503139a0958425
Autor:
Taichi Kato, Yoshihide Mitani, Masahiro Masuya, Junko Maruyama, Hirofumi Sawada, Hiroyuki Ohashi, Yukiko Ikeyama, Shoichiro Otsuki, Noriko Yodoya, Tsutomu Shinohara, Eri Miyata, Erquan Zhang, Naoyuki Katayama, Hideto Shimpo, Kazuo Maruyama, Yoshihiro Komada, Masahiro Hirayama
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
The aim of this study was to investigate whether a dual endothelin receptor antagonist bosentan modulates the kinetics of bone marrow-derived stem cells in inhibiting the development of pulmonary hypertension. Bone marrow chimeric mice, transplanted
Externí odkaz:
https://doaj.org/article/bf44ce81bd394bbc85490e0ec709ec61
Autor:
Hiroki Shoji, Yoko Yoshida, Takayuki Jujo Sanada, Akira Naito, Junko Maruyama, Erquan Zhang, Kengo Sumi, Seiichiro Sakao, Kazuo Maruyama, Hiroyoshi Hidaka, Koichiro Tatsumi
Publikováno v:
Cells, Vol 11, Iss 1, p 66 (2021)
Pulmonary arterial hypertension (PAH) is characterized by elevated pulmonary arterial pressure and right heart failure. Selective pulmonary vasodilators have improved the prognosis of PAH; however, they are not able to reverse pulmonary vascular remo
Externí odkaz:
https://doaj.org/article/c606b099d8604ba3880cb1ddc26466da
Autor:
Keiichi Yamanaka, Takehisa Nakanishi, Hiromitsu Saito, Junko Maruyama, Kenichi Isoda, Ayumu Yokochi, Kyoko Imanaka-Yoshida, Kenshiro Tsuda, Masato Kakeda, Ryuji Okamoto, Satoshi Fujita, Yoichiro Iwakura, Noboru Suzuki, Masaaki Ito, Kazuo Maruyama, Esteban C Gabazza, Toshimichi Yoshida, Motomu Shimaoka, Hitoshi Mizutani
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104479 (2014)
The skin is an immune organ that contains innate and acquired immune systems and thus is able to respond to exogenous stimuli producing large amount of proinflammatory cytokines including IL-1 and IL-1 family members. The role of the epidermal IL-1 i
Externí odkaz:
https://doaj.org/article/44539c1c1144487abe8361230c7ef2ad
Autor:
Yasuharu Yamada, Junzo Iemura, Atushi Kambara, Noboru Tateishi, Yuji Kozaki, Masako Yamada, Junko Maruyama, Eiichi Azuma
Publikováno v:
The Journal of ExtraCorporeal Technology. 55:23-29
Background: Postoperative atrial fibrillation (POAF) is defined as new-onset AF in the immediate postoperative period. The relatively high incidence of POAF after cardiac surgery is well described, but pathophysiological mechanisms underlying the ini
Autor:
Takehisa Nakanishi, Shohei Iida, Junko Maruyama, Hayato Urushima, Masako Ichishi, Yoshiaki Matsushima, Kento Mizutani, Yuichi Nakayama, Kyoko Sugioka, Mai Nishimura, Ai Umaoka, Yoichiro Iwakura, Makoto Kondo, Koji Habe, Daisuke Tsuruta, Osamu Yamamoto, Yasutomo Imai, Keiichi Yamanaka
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5434
The skin is one of the major immune organs producing large amounts of proinflammatory and inflammatory cytokines in response to internal or exogenous stimuli, inducing systemic inflammation in various internal organs. In recent years, organ damage as
Autor:
Jane Kabwe, Hirofumi Sawada, Masako Kawai, Kazuo Maruyama, Ayumu Yokochi, Yoshihide Mitani, Amphone Okada, Ayaka Omori, Toshikazu Ito, Junko Maruyama, Erquan Zhang
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-17 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Preventing pulmonary vascular remodeling is a key strategy for pulmonary hypertension (PH). Causes of PH include pulmonary vasoconstriction and inflammation. This study aimed to determine whether cilostazol (CLZ), a phosphodiesterase-3 inh
Autor:
Hironori Oshita, Hirofumi Sawada, Yoshihide Mitani, Naoki Tsuboya, Jane C. Kabwe, Junko Maruyama, Ali Yusuf, Hiromasa Ito, Ryuji Okamoto, Shoichiro Otsuki, Noriko Yodoya, Hiroyuki Ohashi, Kazunobu Oya, Yuhko Kobayashi, Issei Kobayashi, Kaoru Dohi, Yuhei Nishimura, Shinji Saitoh, Kazuo Maruyama, Masahiro Hirayama
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 323(2)
Pulmonary arterial hypertension (PAH) is a fatal disease, which is characterized by occlusive pulmonary vascular disease (PVD) in small pulmonary arteries. It remains unknown whether perinatal insults aggravate occlusive PVD later in life. We tested