Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Junko Kasuya"'
Autor:
Hung-Lin Chen, Junko Kasuya, Patrick Lansdon, Garrett Kaas, Hanxi Tang, Maggie Sodders, Toshihiro Kitamoto
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 4, Pp 1327-1340 (2020)
Voltage-gated sodium (Nav) channels play a central role in the generation and propagation of action potentials in excitable cells such as neurons and muscles. To determine how the phenotypes of Nav-channel mutants are affected by other genes, we perf
Externí odkaz:
https://doaj.org/article/f5ab4e7a195444719b5afd416a7dde6d
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 2 (2009)
The fruit fly Drosophila melanogaster is an excellent model organism to identify genes and genetic pathways important for learning and memory. However, its small size makes surgical treatment and electrophysiological manipulation technically difficul
Externí odkaz:
https://doaj.org/article/c5ed20be311d439997ba7c37fef75f89
Autor:
Maggie Sodders, Hung-Lin Chen, Toshihiro Kitamoto, Junko Kasuya, Garrett A. Kaas, Hanxi Tang, Patrick Lansdon
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 4, Pp 1327-1340 (2020)
Voltage-gated sodium (Nav) channels play a central role in the generation and propagation of action potentials in excitable cells such as neurons and muscles. To determine how the phenotypes of Nav-channel mutants are affected by other genes, we perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41033a68f5b9d98b2451479cc5ec6574
https://doi.org/10.1534/g3.119.401025
https://doi.org/10.1534/g3.119.401025
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fae1cabd3198b96a69a3dbb64dbf8ee
https://doi.org/10.2139/ssrn.4240653
https://doi.org/10.2139/ssrn.4240653
Autor:
Atulya Iyengar, Toshihiro Kitamoto, Patrick Lansdon, Hung-Lin Chen, Junko Kasuya, Chun-Fang Wu
Publikováno v:
Journal of Neurogenetics. 33:164-178
The Drosophila mutant paraShu harbors a dominant, gain-of-function allele of the voltage-gated sodium channel gene, paralytic (para). The mutant flies display severe seizure-like phenotypes...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3f4d2db4719cefccfe4c4e6bf5e756a
https://doi.org/10.1080/01677063.2019.1597082
https://doi.org/10.1080/01677063.2019.1597082
Autor:
Hung-Lin Chen, Patrick Lansdon, Toshihiro Kitamoto, Maggie Sodders, Hanxi Tang, Garrett A. Kaas, Junko Kasuya
Voltage-gated sodium (Nav) channels play a central role in the generation and propagation of action potentials in excitable cells such as neurons and muscles. To determine how the phenotypes of Nav-channel mutants are affected by other genes, we perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0679dea38d69407516bf0e3f176f592
https://doi.org/10.1101/2020.01.21.906156
https://doi.org/10.1101/2020.01.21.906156
Autor:
Junko, Kasuya, Atulya, Iyengar, Hung-Lin, Chen, Patrick, Lansdon, Chun-Fang, Wu, Toshihiro, Kitamoto
Publikováno v:
J Neurogenet
The Drosophila mutant para(Shu) harbors a dominant, gain-of-function allele of the voltage-gated sodium channel gene, paralytic (para). The mutant flies display severe seizure-like phenotypes, including neuronal hyperexcitability, spontaneous spasms,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::575adddde738e8072682287d3f8f535c
https://pubmed.ncbi.nlm.nih.gov/31096839
https://pubmed.ncbi.nlm.nih.gov/31096839
Autor:
J. Robert Manak, Toshihiro Kitamoto, Anthony J. Lilienthal, Atulya Iyengar, Alexander G. Bassuk, Salleh N. Ehaideb, Elizabeth A. Wignall, William H. Evans, Haley Koerselman, Junko Kasuya
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Genetically tractable fruit flies have been used for decades to study seizure disorders. However, there is a paucity of data specifically correlating fly and human seizure phenotypes. We have previously shown that mutation of orthologous PR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96453f706e674915575305f5fd09ba28
https://doi.org/10.1002/acn3.334
https://doi.org/10.1002/acn3.334
Autor:
Garrett A, Kaas, Junko, Kasuya, Patrick, Lansdon, Atsushi, Ueda, Atulya, Iyengar, Chun-Fang, Wu, Toshihiro, Kitamoto
Publikováno v:
eNeuro
Shudderer (Shu) is an X-linked dominant mutation in Drosophila melanogaster identified more than 40 years ago. A previous study showed that Shu caused spontaneous tremors and defects in reactive climbing behavior, and that these phenotypes were signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89de4cd1c9bedf4c6eed984015b9ae95
https://pubmed.ncbi.nlm.nih.gov/27844061
https://pubmed.ncbi.nlm.nih.gov/27844061
Publikováno v:
Journal of Neurogenetics. 24:33-41
Nociception is a mechanism fundamental to the ability of animals to avoid noxious stimuli capable of causing serious tissue damage. It has been established that in the fruit fly Drosophila melanogaster, the transient receptor potential (TRP) channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43832fda70544288070d35f6ebb921a4
https://doi.org/10.3109/01677060903419751
https://doi.org/10.3109/01677060903419751