Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Junki Maruyama"'
Autor:
Vladimir Perovic, Kristina Stevanovic, Natalya Bukreyeva, Slobodan Paessler, Junki Maruyama, Sergi López-Serrano, Ayub Darji, Milan Sencanski, Draginja Radosevic, Simone Berardozzi, Bruno Botta, Mattia Mori, Sanja Glisic
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4911 (2024)
The influenza A virus nonstructural protein 1 (NS1), which is crucial for viral replication and immune evasion, has been identified as a significant drug target with substantial potential to contribute to the fight against influenza. The emergence of
Externí odkaz:
https://doaj.org/article/9eea7d0871e047f4a013bed4a1c970c9
Autor:
Rachel A. Reyna, Kirsten E. Littlefield, Nathan Shehu, Tomoko Makishima, Junki Maruyama, Slobodan Paessler
Publikováno v:
Viruses, Vol 16, Iss 2, p 266 (2024)
Lassa virus (LASV) is a zoonotic pathogen endemic throughout western Africa and is responsible for a human disease known as Lassa fever (LF). Historically, LASV has been emphasized as one of the greatest public health threats in West Africa, with up
Externí odkaz:
https://doaj.org/article/0eba0fa94bca4fe08943835468dcac3e
Autor:
Xia Cao, Junki Maruyama, Heyue Zhou, Yanwen Fu, Lisa Kerwin, Colin Powers, Rachel A. Sattler, John T. Manning, Alok Singh, Reyna Lim, Laura D. Healy, Sachi Johnson, Elizabeth Paz Cabral, Donghui Li, Lucy Lu, Arthur Ledesma, Daniel Lee, Susan Richards, Laura Rivero-Nava, Yan Li, Weiqun Shen, Karen Stegman, Benjamin Blair, Shinji Urata, Magumi Kishimoto-Urata, Jamie Ko, Na Du, Kyndal Morais, Kate Lawrence, Ianne Rivera, Chin-I. Pai, Damien Bresson, Mark Brunswick, Yanliang Zhang, Henry Ji, Slobodan Paessler, Robert D. Allen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Coronavirus disease 2019 (COVID-19) continues to significantly impact the global population, thus countermeasure platforms that enable rapid development of therapeutics against variants of SARS-CoV-2 are essential. We report use of a phage d
Externí odkaz:
https://doaj.org/article/37fca7f29c8b45c4a5a9a070e9d4f804
Autor:
John Tyler Manning, Junki Maruyama, Timothy Wanninger, Rachel A. Reyna, Heather L. Stevenson, Bi-Hung Peng, Emily K. Mantlo, Cheng Huang, Slobodan Paessler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Junin virus (JUNV) is a member of the Arenaviridae family of viruses and is the pathogen responsible for causing Argentine hemorrhagic fever, a potentially lethal disease endemic to Argentina. A live attenuated vaccine for human use, called Candid#1,
Externí odkaz:
https://doaj.org/article/2d710306a8a443ac96bf8436d9e66e77
Autor:
Megumi Kishimoto-Urata, Shinji Urata, Ryoji Kagoya, Fumiaki Imamura, Shin Nagayama, Rachel A. Reyna, Junki Maruyama, Tatsuya Yamasoba, Kenji Kondo, Sanae Hasegawa-Ishii, Slobodan Paessler
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The impact of SARS-CoV-2 on the olfactory pathway was studied over several time points using Syrian golden hamsters. We found an incomplete recovery of the olfactory sensory neurons, prolonged activation of glial cells in the olfactory bulb,
Externí odkaz:
https://doaj.org/article/12fd7fed7a19441e9c5c48c110348f87
Autor:
Rachel A. Reyna, Megumi Kishimoto-Urata, Shinji Urata, Tomoko Makishima, Slobodan Paessler, Junki Maruyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for a pandemic affecting billions of people worldwide. Apart from the extreme global economic impact, the pandemic will likely have a lasting impact through long-ter
Externí odkaz:
https://doaj.org/article/651bb99cbac24de89e0f4b794c2dc9b0
Autor:
Timothy G. Wanninger, Daniel E. Millian, Omar A. Saldarriaga, Junki Maruyama, Takeshi Saito, Rachel A. Reyna, Satoshi Taniguchi, Esteban Arroyave, Melanie E. Connolly, Heather L. Stevenson, Slobodan Paessler
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Macrophages contribute to Ebola virus disease through their susceptibility to direct infection, their multi-faceted response to ebolaviruses, and their association with pathological findings in tissues throughout the body. Viral attachment and entry
Externí odkaz:
https://doaj.org/article/0e598ebfe61d445e90ebbd0d0dd49c8e
Autor:
Junki Maruyama, Rachel A Reyna, Megumi Kishimoto-Urata, Shinji Urata, John T Manning, Nantian Harsell, Rebecca Cook, Cheng Huang, Janko Nikolich-Zugich, Tomoko Makishima, Slobodan Paessler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010557 (2022)
Lassa virus (LASV) is the causative agent of Lassa fever (LF), which presents as a lethal hemorrhagic disease in severe cases. LASV-induced hearing loss in survivors is a huge socioeconomic burden, however, the mechanism(s) leading to hearing loss is
Externí odkaz:
https://doaj.org/article/c6d8f5e163c24ea4afd188ae99ac0294
Autor:
Takeshi Saito, Rachel A. Reyna, Satoshi Taniguchi, Kirsten Littlefield, Slobodan Paessler, Junki Maruyama
Publikováno v:
Vaccines, Vol 11, Iss 3, p 635 (2023)
The viral family Arenaviridae contains several members that cause severe, and often lethal, diseases in humans. Several highly pathogenic arenaviruses are classified as Risk Group 4 agents and must be handled in the highest biological containment fac
Externí odkaz:
https://doaj.org/article/46d512d400454aedb1023576dcadb5e1
Autor:
Rachel A. Reyna, Junki Maruyama, Emily K. Mantlo, John T. Manning, Satoshi Taniguchi, Tomoko Makishima, Igor S. Lukashevich, Slobodan Paessler
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2433 (2022)
Lassa virus (LASV) is a zoonotic virus endemic to western Africa that can cause a potentially lethal and hemorrhagic disease, Lassa fever (LF). Survivors suffer a myriad of sequelae, most notably sudden onset sensorineural hearing loss (SNHL), the me
Externí odkaz:
https://doaj.org/article/079040d536fa4f48af28498cfb54eb63