Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Junjie Nie"'
Autor:
Shangshang Hu, Qianni Xiao, Rui Gao, Jian Qin, Junjie Nie, Yuhan Chen, Jinwei Lou, Muzi Ding, Yuqin Pan, Shukui Wang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract Background Numerous studies have indicated that cancer-associated fibroblasts (CAFs) play a crucial role in the progression of colorectal cancer (CRC). However, there are still many unknowns regarding the exact role of CAF subtypes in CRC. M
Externí odkaz:
https://doaj.org/article/b0bcef19083c42288cbfd5709e86b5b7
Autor:
Junjie Nie, Xinwei Liu, Mu Xu, Xiaoxiang Chen, Shangshang Hu, Xinliang Gu, Huiling Sun, Tianyi Gao, Yuqin Pan, Shukui Wang
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102097- (2024)
Background: Synthetic lethality (SL) emerges as a novel concept being explored to combat cancer progression and resistance to conventional therapy. Despite the efficacy of chemotherapy in select cases of colorectal cancer (CRC), a substantial proport
Externí odkaz:
https://doaj.org/article/c52fdd620065474c93cffcd50cdfa24b
Autor:
Xiangxiang Liu, Jian Qin, Junjie Nie, Rui Gao, Shangshang Hu, Huiling Sun, Shukui Wang, Yuqin Pan
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundLiver metastasis (LM) is a leading cause of cancer-related deaths in CRC patients, whereas the associated mechanisms have not yet been fully elucidated. Therefore, it is urgently needed to deeply explore novel metastasis accelerators and th
Externí odkaz:
https://doaj.org/article/ab50999adcb94d8b97521c311c1a7846
Publikováno v:
Analytical Cellular Pathology, Vol 2023 (2023)
Currently, 80%–90% of liver cancers are hepatocellular carcinomas (HCC). HCC patients develop insidiously and have an inferior prognosis. The methyltransferase-like (METTL) family principal members are strongly associated with epigenetic and tumor
Externí odkaz:
https://doaj.org/article/34d6b5d3e407414ca4d7f9bd52baa130
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 824-837 (2022)
As the most prevalent type of RNA modification in eukaryotes, N6-methyladenosine (m6A) can modulate RNA fates such as processing, splicing, maturation, export, stability, translation, and degradation. Circular RNAs (circRNAs), a novel type of non-cod
Externí odkaz:
https://doaj.org/article/9234a453a7eb4eabaaaa30cb21bc805b
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: The traditional TNM staging system is often insufficient to differentiate the survival discrepancies of colorectal cancer (CRC) patients at TNM stage I/II. Our study aimed to reclassify stage I/II CRC patients into several subgroups with
Externí odkaz:
https://doaj.org/article/fe90441b78854ae0a8e66e493efb9f6f
Autor:
Tianyi Gao, Dan Yuan, Bangshun He, Yingdong Gao, Caidong Liu, Huilin Sun, Junjie Nie, Shukui Wang, Zhenlin Nie
Publikováno v:
Heliyon, Vol 8, Iss 3, Pp e09033- (2022)
The emergence of 5-Fluorouracil (5-FU) resistance is the barrier to effective clinical outcomes for colorectal cancer (CRC) patients. Autophagy was found to be involved in protecting tumor cells from 5-FU. However, the specific role of autophagy-rela
Externí odkaz:
https://doaj.org/article/bddfa64c56554b8dac9a49c2802cb9ea
Autor:
Pei Tan, Huiling Sun, Mu Xu, Xiangxiang Liu, Jian Qin, Junjie Nie, Xiaodan Qin, Shukui Wang, Yuqin Pan
Publikováno v:
Cancer Science. 114:1396-1409
Emerging evidence has suggested that circular RNAs (circRNAs) have vital functions during the initiation and progression of various diseases. However, circRNA potential mechanisms in colorectal cancer (CRC) are largely unknown. Here, we sought to inv
Autor:
Junjie Nie, Jude Juventus Aweya, Zhixue Yu, Hui Zhou, Fan Wang, Defu Yao, Zhihong Zheng, Shengkang Li, Hongyu Ma, Yueling Zhang
Publikováno v:
The Journal of Immunology. 209:476-487
Although invertebrates’ innate immunity relies on several immune-like molecules, the diversity of these molecules and their immune response mechanisms are not well understood. Here, we show that Penaeus vannamei hemocyanin (PvHMC) undergoes specifi
Autor:
Junjie Nie, Haoyu Wang, Pei Tan, Huiling Sun, Xiangxiang Liu, Tianyi Gao, Yuqin Pan, Shukui Wang
Thioredoxin reductase (TXNRD1) acts as part of a major enforcer of redox homeostasis in the intracellular environment. However, its prognostic value and the relationship between TXNRD1 and core ferroptosis-related genes in hepatocellular carcinoma re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0871100419cd5fb85835fb6a6c86cc6
https://doi.org/10.21203/rs.3.rs-2965547/v1
https://doi.org/10.21203/rs.3.rs-2965547/v1