Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Junji Yokozawa"'
Autor:
Makoto Yagi, Nana Kanno, Daisuke Iwano, Takao Yaoita, Yoshiyuki Ueno, Yu Sasaki, Kazuhiro Sakuta, Yasuhiko Abe, Junji Yokozawa, Shoichi Nishise, Hiroaki Takeda, Kazuya Yoshizawa, Eiki Nomura, Takeshi Sato, Ko Nagino, Sumio Kawata
Publikováno v:
The Tohoku Journal of Experimental Medicine. 235:127-134
The prevalence of colorectal malignancies is increasing in the world. The parallel increase of metabolic syndrome gives a speculation between these two conditions, although the precise mechanism is still unclear. Interleukin-6 (IL-6) is a cytokine kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e85f3bbcc29a26302ad23107fc94f80
https://doi.org/10.1620/tjem.235.127
https://doi.org/10.1620/tjem.235.127
Autor:
Sumio Kawata, Hong-Jin Shu, Hitoshi Togashi, Junji Yokozawa, Junitsu Ito, Hisayoshi Watanabe, Hiroaki Haga, Koji Saito, Etsuko Hattori, Kazuo Okumoto, Takafumi Saito
Publikováno v:
Hepatology Research. 40:432-437
Aim: Musashi1 is an RNA-binding protein that regulates the Notch signaling pathway in stem cells. Our previous study revealed that Musashi1 is expressed in early hepatocytes during liver development in the mouse. However, whether this unique protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2879ca422be4ea97470dc0054bd4b31e
https://doi.org/10.1111/j.1872-034x.2009.00612.x
https://doi.org/10.1111/j.1872-034x.2009.00612.x
Autor:
Jun Takano, Hiroaki Takeda, Sayaka Otake, Yu Sasaki, Shoichi Nishise, Takao Yaoita, Junji Yokozawa, Daisuke Iwano, Takeshi Sato, Shoichiro Fujishima, Tadahisa Fukui, Tomohiko Orii, Ko Nagino, Sumio Kawata
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
Increased oxidative stress is generally thought to be associated with tumorigenesis. In this cross-sectional study, we evaluated plasma 8-hydroxydeoxyguanosine (8-OHdG) levels in patients with colorectal adenoma and cancer, as a surrogate marker of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86714c26d246d63fd8ee54e1a3c9d494
https://doi.org/10.3164/jcbn.10-12
https://doi.org/10.3164/jcbn.10-12
Autor:
Kumiko Ohwada, Takashi Sasaki, Junitsu Ito, Takafumi Saito, Sumio Kawata, Yayoi Sasaki, Junji Yokozawa
Publikováno v:
Journal of Gastroenterology. 44:583-591
It has been reported that angiotensin II type 1 receptor blocker (ARB) can ameliorate hepatic steatosis and insulin resistance. Stearoyl-CoA desaturase 1 (SCD-1), which catalyzes the cellular synthesis of monounsaturated fatty acids, affects lipid me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6ef5734ddba2b6c950b46aee315ad8
https://doi.org/10.1007/s00535-009-0042-x
https://doi.org/10.1007/s00535-009-0042-x
Autor:
Rumiko Saito, Kaname Kojima, Kaoru Tsuda, Atsushi Hozawa, Yukuto Sato, Nobuo Fuse, Yosuke Kawai, Shin Ito, Shigeo Kure, Junji Yokozawa, Inaho Danjoh, Masao Nagasaki, Hideyasu Kiyomoto, Yoko Kuroki, Takahiro Mimori, Yumi Yamaguchi-Kabata, Xiaoqing Pan, Fumiki Katsuoka, Kengo Kinoshita, Naoki Nariai, Shinichi Kuriyama, Sakae Saito, Osamu Tanabe, Jun Yasuda, Masayuki Yamamoto, Naoko Minegishi, James Douglas Engel, Satoshi Nishikawa, Nobuo Yaegashi
Publikováno v:
Nature Communications
The Tohoku Medical Megabank Organization reports the whole-genome sequences of 1,070 healthy Japanese individuals and construction of a Japanese population reference panel (1KJPN). Here we identify through this high-coverage sequencing (32.4 × on av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f188f3557eb7b4f54ab0c08192339df8
http://europepmc.org/articles/PMC4560751
http://europepmc.org/articles/PMC4560751
Autor:
Yukuto Sato, Kengo Kinoshita, Xiaoqing Pan, Masayuki Yamamoto, Inaho Danjoh, Shin Ito, Mitsuyo Matsumoto, Kaoru Tsuda, Naoki Nariai, Tomo Saito, Matsuyuki Shirota, Rumiko Saito, Satoshi Nishikawa, Junji Yokozawa, Ikuko N. Motoike, Hisaaki Kudo, Masao Nagasaki, Ichiko Nishijima, Kaname Kojima, Naoko Minegishi, Osamu Tanabe, Jun Yasuda, Kazuhiko Igarashi, Nobuo Fuse, Sakae Saito, Fumiki Katsuoka, Yumi Yamaguchi-Kabata
Publikováno v:
BMC Genomics
Background Validation of single nucleotide variations in whole-genome sequencing is critical for studying disease-related variations in large populations. A combination of different types of next-generation sequencers for analyzing individual genomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56966fe35554c93d5385dbd34859f8c
https://doi.org/10.1186/1471-2164-15-673
https://doi.org/10.1186/1471-2164-15-673
Autor:
Masao Nagasaki, Xiaoqing Pan, Jun Yasuda, Shin Ito, Kaoru Tsuda, Masayuki Yamamoto, Junji Yokozawa, Fumiki Katsuoka
Publikováno v:
Analytical biochemistry. 466
Library quantitation is a critical step to obtain high data output in Illumina HiSeq sequencers. Here, we introduce a library quantitation method that uses the Illumina MiSeq sequencer designated as quantitative MiSeq (qMiSeq). In this procedure, 96
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4e8eeceb18b7e10bcc821f1b50da9d
https://pubmed.ncbi.nlm.nih.gov/25173513
https://pubmed.ncbi.nlm.nih.gov/25173513
Publikováno v:
Journal of Blood & Lymph.
Lymphatic vessels not only play a physiological role in maintenance of homeostasis and the immune response together with blood vessels, but also participate in the development of pathological states such as inflammation and cancer metastasis [1]. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca2c526f6d89141a381ceaaf3ea9b710
https://doi.org/10.4172/2165-7831.1000127
https://doi.org/10.4172/2165-7831.1000127
Publikováno v:
Biochemical and biophysical research communications. 425(2)
It has been suggested that intestinal lymph flow plays an important role in insulin secretion and glucose metabolism after meals. In this study, we investigated the influence of ligation of the mesenteric lymph duct on glucose metabolism and islet β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e71fd5d78bdec424431d23c1b496f4
https://pubmed.ncbi.nlm.nih.gov/22842578
https://pubmed.ncbi.nlm.nih.gov/22842578
Autor:
Masaaki Aoyama, Hiroaki Ohya, Norikazu Kainuma, Akihiko Suzuki, Hala Badawi, Yasuhito Tanaka, Takao Akatsuka, Kazuhiko Sugahara, Masashi Mizokami, Junji Yokozawa, Hitoshi Togashi, Ichiro Yamaguchi, Chika Hashimoto, Takafumi Saito, Sumio Kawata
Publikováno v:
Journal of hepatology. 49(1)
We investigated what can be revealed by extending the sensitivity of HBsAg detection to below the present limit.We examined the sensitivity of this immunoassay in comparison with real-time PCR detection of HBV DNA using serially diluted sera from HBV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85abe18ef6ca6cb74bf7cae6b52049f7
https://pubmed.ncbi.nlm.nih.gov/19012990
https://pubmed.ncbi.nlm.nih.gov/19012990