Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Junji Kishimoto"'
Autor:
Shota Ikeda, Keisuke Shinohara, Koshiro Tagawa, Takeshi Tohyama, Junji Kishimoto, Masaya Kazurayama, Shinji Tanaka, Masamitsu Yamaizumi, Hirokazu Nagayoshi, Kensuke Toyama, Shouji Matsushima, Hiroyuki Tsutsui, Shintaro Kinugawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Electrocardiographic left ventricular hypertrophy (LVH) could predict adverse renal outcomes in patients with hypertension. This study aimed to investigate the association between electrocardiographic LVH and future decline in renal function
Externí odkaz:
https://doaj.org/article/0008dd0ed5604ee4bc632507d41cf8aa
Autor:
Kazuya Yokota, Hiroaki Sakai, Osamu Kawano, Yuichiro Morishita, Muneaki Masuda, Tetsuo Hayashi, Kensuke Kubota, Ryosuke Ideta, Yuto Ariji, Ryuichiro Koga, Satoshi Murai, Ryusei Ifuku, Masatoshi Uemura, Junji Kishimoto, Hiroko Watanabe, Yasuharu Nakashima, Takeshi Maeda
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0298836 (2024)
Traumatic spinal cord injury (TSCI) causes an insult to the central nervous system, often resulting in devastating temporary or permanent neurological impairment and disability, which places a substantial financial burden on the health-care system. T
Externí odkaz:
https://doaj.org/article/709772cbeca746358c6bd4e08a8d2bee
Autor:
Mitsuru Esaki, Eikichi Ihara, Noriaki Manabe, Noriyuki Kawami, Katsuhiko Iwakiri, Junichi Akiyama, Shiko Kuribayashi, Toshio Uraoka, Haruei Ogino, Takatoshi Chinen, Akiko Misumi, Hiroko Watanabe, Maya Suzuki, Junji Kishimoto, Yoshihiro Ogawa
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background We have determined that the impaired accommodation of the lower esophageal sphincter (LES) underlies the pathogenesis of esophagogastric junction outflow obstruction (EGJOO). We have also found that acotiamide may treat EGJOO by i
Externí odkaz:
https://doaj.org/article/f181278c7e594f55bf5d4cf7a45160ec
Autor:
Yoshimasa Shiraishi, Junji Kishimoto, Takayuki Shimose, Yukihiro Toi, Shunichi Sugawara, Isamu Okamoto
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-5 (2022)
Abstract Background First-line treatment of nonsquamous non–small cell lung cancer (NSCLC) has undergone a paradigm shift to platinum combination therapy together with immune checkpoint inhibitors (ICIs). However, phase III studies of combinations
Externí odkaz:
https://doaj.org/article/fad4a98eec924a8eac91b100e7450863
Autor:
Hiroaki Kubo, Hiromi Urata, Motohiro Sakai, Shunsuke Nonaka, Junji Kishimoto, Kazuhiko Saito, Masaru Tateno, Keiji Kobara, Daisuke Fujisawa, Naoki Hashimoto, Yuriko Suzuki, Yoko Honda, Tomohiro Nakao, Kotaro Otsuka, Shigenobu Kanba, Toshihide Kuroki, Takahiro A. Kato
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2023)
BackgroundsHikikomori, pathological social withdrawal, is becoming a crucial mental health issue in Japan and worldwide. We have developed a 3-day family intervention program for hikikomori sufferers based on Mental Health First Aid (MHFA) and Commun
Externí odkaz:
https://doaj.org/article/eb5d23f67d4d497cbdbeaf7ba5f2f2a0
Autor:
Yusuke Akiyama, Shunsuke Katsuki, Tetsuya Matoba, Yasuhiro Nakano, Susumu Takase, Soichi Nakashiro, Mitsutaka Yamamoto, Yasushi Mukai, Shujiro Inoue, Keiji Oi, Taiki Higo, Masao Takemoto, Nobuhiro Suematsu, Kenichi Eshima, Kenji Miyata, Makoto Usui, Kenji Sadamatsu, Toshiaki Kadokami, Kiyoshi Hironaga, Ikuyo Ichi, Koji Todaka, Junji Kishimoto, Hiroyuki Tsutsui
Publikováno v:
Nutrients, Vol 15, Iss 13, p 2997 (2023)
Oxysterols have been implicated in the pathogenesis of cardiovascular diseases. Serum levels of oxysterols could be positively correlated with cholesterol absorption and synthesis. However, physiological regulation of various serum oxysterols is larg
Externí odkaz:
https://doaj.org/article/4ade8779f9ba4675b38290dff44df39a
Autor:
Takeshi Tohyama, Tomomi Ide, Masataka Ikeda, Hidetaka Kaku, Nobuyuki Enzan, Shouji Matsushima, Kouta Funakoshi, Junji Kishimoto, Koji Todaka, Hiroyuki Tsutsui
Publikováno v:
ESC Heart Failure, Vol 8, Iss 5, Pp 4077-4085 (2021)
Abstract Aims Individual risk stratification is a fundamental strategy in managing patients with heart failure (HF). Artificial intelligence, particularly machine learning (ML), can develop superior models for predicting the prognosis of HF patients,
Externí odkaz:
https://doaj.org/article/808b126ae4174e40958441d28102a34b
Autor:
Keiichi Fukuda, Satoshi Yasuda, Hiroyuki Tsutsui, Toyoaki Murohara, Kohtaro Abe, Koichiro Tatsumi, Junji Kishimoto, Yu Taniguchi, Yuichi Tamura, Koji Todaka, Shun Minatsuki, Kazuya Hosokawa, Yuko Kobayakawa, Takumi Inami, Nobutaka Ikeda
Publikováno v:
BMJ Open, Vol 12, Iss 7 (2022)
Introduction Chronic thromboembolic pulmonary hypertension (CTEPH) is a complication of prior pulmonary thromboembolism (PE), caused by incomplete clot dissolution after PE. In patients with CTEPH, lifelong anticoagulation is mandatory to prevent rec
Externí odkaz:
https://doaj.org/article/6b5f9a98c35d4546ad6c27984161fa58
Autor:
Kiminori Kimura, Tatsuya Kanto, Shinji Shimoda, Kenichi Harada, Masamichi Kimura, Koji Nishikawa, Jun Imamura, Eiichi Ogawa, Masanao Saio, Yoshihiro Ikura, Takuji Okusaka, Kazuaki Inoue, Tetsuya Ishikawa, Ichiro Ieiri, Junji Kishimoto, Koji Todaka, Terumi Kamisawa
Publikováno v:
EBioMedicine, Vol 80, Iss , Pp 104069- (2022)
Summary: Background: We conducted an exploratory study to assess the safety tolerability, and anti-fibrotic effects of PRI-724, a CBP/β-catenin inhibitor, in patients with hepatitis C virus (HCV)- and hepatitis B virus (HBV)-induced cirrhosis. Metho
Externí odkaz:
https://doaj.org/article/a68a8544980a4b5a8162b15098cfe871
Autor:
Hiroshi Matsuoka, Yutaka Ogata, Michio Nakamura, Yoshihisa Shibata, Yoshinori Munemoto, Hiroyuki Bando, Koji Nishijima, Hiroyuki Okuda, Itsuro Terada, Takeru Shiroiwa, Junji Kishimoto, Kotaro Maeda
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 4, Iss 2, Pp 79-84 (2020)
Objectives: In recent years, CapeOX therapy for patients with colorectal cancer is widely used. We previously reported that a multidisciplinary approach decreases the worsening of adverse events and increases patient satisfaction. In this study, we c
Externí odkaz:
https://doaj.org/article/c21b3df7ca2c4269ac978e9b684d4d46