Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Junji Ichihara"'
Autor:
Yuka Kimura, Shunsuke Nakazawa, Kantaro Nishigori, Yuki Mori, Junji Ichihara, Yoshichika Yoshioka
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 2, Pp n/a-n/a (2023)
Abstract The dopamine D1 receptor (D1R) is associated with schizophrenia, Parkinson's disease, and attention deficit hyperactivity disorder. Although the receptor is considered a therapeutic target for these diseases, its neurophysiological function
Externí odkaz:
https://doaj.org/article/1218c93d99e040d4b942b565981e822b
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127048 (2015)
Biomarkers useful for diagnosis and evaluation of treatment for patients with Fabry disease are urgently needed. Recently, plasma globotriaosylsphingosine (lyso-Gb3) and lyso-Gb3-related analogues have attracted attention as promising biomarkers of F
Externí odkaz:
https://doaj.org/article/f6938910f51742d6954bb853c3532174
Autor:
Yuka Kimura, Shunsuke Nakazawa, Kantaro Nishigori, Yuki Mori, Junji Ichihara, Yoshichika Yoshioka
Publikováno v:
Pharmacology Research & Perspectives. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc9a56ace9c3a57a4359e2791ffe83a7
https://doi.org/10.1002/prp2.1055
https://doi.org/10.1002/prp2.1055
Application of Zwitterionic Polymer Hydrogels to Optical Tissue Clearing for 3D Fluorescence Imaging
Autor:
Tetsuro Nariai, Akikazu Matsumoto, Chie Kojima, Takayuki Koda, Junji Ichihara, Kikuya Sugiura
Publikováno v:
Macromolecular bioscience. 21(9)
Zwitterionic polymers have both anion and cation groups in the side chain and have been used in various biomedical applications because of the unique properties. In this study, zwitterionic polymer hydrogels are applied to optical tissue clearing for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e3b3e7ef0befc4eeac82547c0b6bb6
https://pubmed.ncbi.nlm.nih.gov/34155811
https://pubmed.ncbi.nlm.nih.gov/34155811
Autor:
Masayuki Mizuno, Tsuyoshi Iwasaki, Takeshi Okanoue, Kazuto Yamazaki, Junji Ichihara, Toshihide Shima, Hayao Ebise, Keito Yoshimura
Publikováno v:
Hepatology. 63:462-473
It is important that patients with nonalcoholic steatohepatitis (NASH) are diagnosed and treated early to prevent serious complications, such as liver cirrhosis or hepatocellular carcinoma. However, current methods for NASH diagnosis are invasive giv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3defce710b41db5cc3850d4f289fe50
https://doi.org/10.1002/hep.28226
https://doi.org/10.1002/hep.28226
Publikováno v:
Analytical Biochemistry. 491:23-30
The glucagon-like peptide-1 receptor (GLP-1R) is an important physiologic regulator of insulin secretion and a major therapeutic target for diabetes mellitus. GLP-1 (7-36) amide (active form of GLP-1) is truncated to GLP-1 (9-36) amide, which has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17079a725dac394dc0d01b9f7d4b7b6
https://doi.org/10.1016/j.ab.2015.08.026
https://doi.org/10.1016/j.ab.2015.08.026
Autor:
Toshihiro Kai, Masayuki Mizuno, Hayao Ebise, Toshihide Shima, Mikio Aoki, Takeshi Okanoue, Junji Ichihara
Publikováno v:
Journal of gastroenterology. 53(1)
Recently we reported novel noninvasive scoring systems for diagnosing nonalcoholic steatohepatitis (NASH) and related fibrosis, namely FM-NASH index and FM-fibro index. They are highly accurate, however, they contain some items not widely used in cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344f3dc19e31c34ab7c15081f42b2f94
https://pubmed.ncbi.nlm.nih.gov/28589339
https://pubmed.ncbi.nlm.nih.gov/28589339
Autor:
Toru Kimura, Hironori Ishikawa, Masaharu Kanaoka, Koji Hayashi, Takao Kawamura, Mutsuo Taiji, Junji Ichihara, Masayuki Heishi
Publikováno v:
The Journal of Toxicological Sciences. 33:339-347
Large-scale clinical studies have shown that the biguanide drug metformin, widely used for type 2 diabetes, to be very safe. By contrast, another biguanide, phenformin, has been withdrawn from major markets because of a high incidence of serious adve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e545246c56e132b516af524b4b6b78
https://doi.org/10.2131/jts.33.339
https://doi.org/10.2131/jts.33.339
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 63
Dopamine plays a key role in the regulation of sleep–wake states, as revealed by the observation that dopamine-releasing agents such as methylphenidate have wake-promoting effects. However, the precise mechanisms for the wake-promoting effect produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48f0fae0bd0221c73f9612a7d634ec6
https://pubmed.ncbi.nlm.nih.gov/25985889
https://pubmed.ncbi.nlm.nih.gov/25985889
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127048 (2015)
PLoS ONE
PLoS ONE
Biomarkers useful for diagnosis and evaluation of treatment for patients with Fabry disease are urgently needed. Recently, plasma globotriaosylsphingosine (lyso-Gb3) and lyso-Gb3-related analogues have attracted attention as promising biomarkers of F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ca1f50bd10752b9768d7049bae44f0
http://europepmc.org/articles/PMC4428877?pdf=render
http://europepmc.org/articles/PMC4428877?pdf=render