Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Junji, Iwahara"'
Autor:
Binhan Yu, Junji Iwahara
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2279-2285 (2021)
Ionic interactions are crucial to biological functions of DNA, RNA, and proteins. Experimental research on how ions behave around biological macromolecules has lagged behind corresponding theoretical and computational research. In the 21st century, q
Externí odkaz:
https://doaj.org/article/5dd73fd8813b4c42b92efc892df448ae
Publikováno v:
Methods. 210:1-9
Nuclear magnetic resonance (NMR) spectroscopy is a versatile tool used to investigate the dynamic properties of biological macromolecules and their complexes. NMR relaxation data can provide order parameters S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe4e6ce3deb54d1e2d7c6df2b6776c9
https://doi.org/10.1016/j.ymeth.2022.12.004
https://doi.org/10.1016/j.ymeth.2022.12.004
Publikováno v:
The Journal of Physical Chemistry Letters. 13:10025-10029
Electrostatic potentials around macromolecules in the presence of mobile charges are difficult to assess especially for highly charged systems. Here, we report measurements of local electrostatic potentials around DNA by paramagnetic NMR. Through qua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6682ddbac6127a73d77b0a7948fe7767
https://doi.org/10.1021/acs.jpclett.2c02623
https://doi.org/10.1021/acs.jpclett.2c02623
Publikováno v:
Biophysical Journal. 121:3562-3570
Counterions are important constituents for the structure and function of nucleic acids. Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c221c21f494fbfd8efcf596405e1151
https://doi.org/10.1016/j.bpj.2022.06.022
https://doi.org/10.1016/j.bpj.2022.06.022
Autor:
Binhan Yu, Junji Iwahara
Publikováno v:
Biopolymers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34a0449bcd76e1e81d939ae19f5a3861
https://doi.org/10.1002/bip.23553
https://doi.org/10.1002/bip.23553
Publikováno v:
Biochemistry. 61:1415-1418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb90a6f9f87262ee3309096b68693741
https://doi.org/10.1021/acs.biochem.2c00299
https://doi.org/10.1021/acs.biochem.2c00299
Publikováno v:
J Phys Chem B
Experimental validation of theoretical models for protein electrostatics remains rare. Recently, we have developed a paramagnetic NMR-based method for de novo determination of effective near-surface electrostatic potentials, which allows for straight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb2242973945a1c1156611560feb7b2
https://doi.org/10.1021/acs.jpcb.1c10930
https://doi.org/10.1021/acs.jpcb.1c10930
Publikováno v:
Nucleic Acids Research.
In eukaryotes, many DNA/RNA-binding proteins possess intrinsically disordered regions (IDRs) with large negative charge, some of which involve a consecutive sequence of aspartate (D) or glutamate (E) residues. We refer to them as D/E repeats. The fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d0e6a90d222c25c261c76c7832aed7
https://doi.org/10.1093/nar/gkad045
https://doi.org/10.1093/nar/gkad045
Publikováno v:
Analytical Chemistry. 94:2444-2452
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2195c6f364d37b5cf6e2750f62b5a7fd
https://doi.org/10.1021/acs.analchem.1c04197
https://doi.org/10.1021/acs.analchem.1c04197
Publikováno v:
J Phys Chem Lett
Hindered rotation about a sp(2) C-N bond is known to occur in arginine (Arg), asparagine (Asn), and glutamine (Gln) side chains of proteins. However, very little is known about the rotational dynamics of Asn and Gln side-chain NH(2) groups. Here, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4058c56bc6af007130291fc60dd0c557
https://doi.org/10.1021/acs.jpclett.1c03467
https://doi.org/10.1021/acs.jpclett.1c03467