Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Junji, Hirota"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract In the mouse, 129 functional class I odorant receptor (OR) genes reside in a ~ 3 megabase huge gene cluster on chromosome 7. The J element, a long-range cis-regulatory element governs the singular expression of class I OR genes by exerting i
Externí odkaz:
https://doaj.org/article/9b3dd9640ae447dd9ebacee6f028c225
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0267683 (2022)
Continuous turnover of taste bud cells in the oral cavity underlies the homeostasis of taste tissues. Previous studies have demonstrated that Sox2+ stem cells give rise to all types of epithelial cells including taste bud cells and non-gustatory epit
Externí odkaz:
https://doaj.org/article/38539b41f19e415b92e68798891ddb9c
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240848 (2020)
Taste bud cells arise from local epithelial stem cells in the oral cavity and are continuously replaced by newborn cells throughout an animal's life. However, little is known about the molecular and cellular mechanisms of taste cell turnover. Recentl
Externí odkaz:
https://doaj.org/article/99d3eef5a8464e6facb55567a509ae93
Autor:
Tetsuo Iwata, Yoshihito Niimura, Chizuru Kobayashi, Daichi Shirakawa, Hikoyu Suzuki, Takayuki Enomoto, Kazushige Touhara, Yoshihiro Yoshihara, Junji Hirota
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
“Each olfactory sensory neuron expresses a single odorant receptor gene from either class I or class II genes. Here, the authors identify an enhancer for mouse class I genes, that is highly conserved, and regulates most class I genes expression by
Externí odkaz:
https://doaj.org/article/24a502d9bbcc4cf79ef5efbba1d65d40
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189340 (2017)
Transient receptor potential channel M5 (Trpm5)-expressing cells, such as sweet, umami, and bitter taste cells in the oropharyngeal epithelium, solitary chemosensory cells in the nasal respiratory epithelium, and tuft cells in the small intestine, th
Externí odkaz:
https://doaj.org/article/faff682709db46548d7e82e236be2929
Publikováno v:
Cell and Tissue Research. 384:643-653
Individual olfactory sensory neurons (OSNs) in the mouse main olfactory epithelium express a single odorant receptor (OR) gene from the repertoire of either class I or class II ORs. The transcription factor Bcl11b determines the OR class to be expres
Publikováno v:
Cell and tissue research. 383(3)
Taste substances are detected by taste receptor cells in the taste buds in the oral epithelium. Individual taste receptor cells contribute to evoking one of the five taste qualities: sweet, umami, bitter, sour, and salty (sodium). They are continuous
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240848 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240848 (2020)
Taste bud cells arise from local epithelial stem cells in the oral cavity and are continuously replaced by newborn cells throughout an animal's life. However, little is known about the molecular and cellular mechanisms of taste cell turnover. Recentl
Autor:
Rei Kajitani, Hiro Kondo, Tetsuo Iwata, Akito Fujita, Yasue Hatanaka, Makoto Ohmoto, Takahiro Kashiwagi, Takehiko Itoh, Ichiro Matsumoto, Takayuki Enomoto, Kanako Nakayama, Junji Hirota, Hidefumi Nishida
Publikováno v:
Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-16 (2019)
Communications Biology, Vol 2, Iss 1, Pp 1-16 (2019)
Each olfactory sensory neuron (OSN) expresses a single odorant receptor (OR) gene from the class I or class II repertoire in mice. The mechanisms that regulate OR class choice in OSNs remain unknown. Here, we show that the transcription factor Bcl11b
Autor:
Hikoyu, Suzuki, Hidefumi, Nishida, Hiro, Kondo, Ryota, Yoda, Tetsuo, Iwata, Kanako, Nakayama, Takayuki, Enomoto, Jiaqi, Wu, Keiko, Moriya-Ito, Masao, Miyazaki, Yoshihiro, Wakabayashi, Takushi, Kishida, Masataka, Okabe, Yutaka, Suzuki, Takehiko, Ito, Junji, Hirota, Masato, Nikaido
Publikováno v:
Molecular biology and evolution. 35(12)
Pheromones are crucial for eliciting social and sexual behaviors in diverse animal species. The vomeronasal receptor type-1 (V1R) genes, encoding members of a pheromone receptor family, are highly variable in number and repertoire among mammals due t