Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Junier Marrero-Gutiérrez"'
Autor:
Rui M Patrício da Silva-Júnior, Ana Carolina Bueno, Clarissa Silva Martins, Fernanda Coelli-Lacchini, Jorge Guilherme Okanobo Ozaki, Danillo Cunha de Almeida-e-Silva, Junier Marrero-Gutiérrez, Antônio Carlos dos Santos, Carlos Garcia-Peral, Hélio Rubens Machado, Marcelo Volpon dos Santos, Paula Lamparelli Elias, Ayrton C Moreira, Leandro M Colli, Ricardo Z N Vêncio, Sonir R Antonini, Margaret de Castro
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 108:1452-1463
Objective To explore pituitary tumors by methylome and transcriptome signatures in a heterogeneous ethnic population. Methods In this retrospective cross-sectional study, clinicopathological features, methylome, and transcriptome were evaluated in pi
Autor:
Ana Carolina Bueno, Mônica F Stecchini, Junier Marrero-Gutiérrez, Candy Bellido More, Leticia Ferro Leal, Débora Cristiane Gomes, Daniel Ferreira de Lima Neto, Silvia Regina Brandalise, Izilda Aparecida Cardinalli, José Andres Yunes, Thais Junqueira, Carlos Alberto Scrideli, Carlos Augusto Fernandes Molina, Fernando Silva Ramalho, Silvio Tucci, Fernanda Borchers Coeli-Lacchini, Ayrton Custodio Moreira, Leandra Ramalho, Ricardo Zorzetto Nicoliello Vêncio, Margaret De Castro, Sonir Roberto R Antonini
Publikováno v:
European Journal of Endocrinology. 186:573-585
Objective Pediatric adrenocortical tumors (pACT) display complex genomic backgrounds, lacking robust prognostic markers and targeted therapeutic options. Vitamin D3 receptor (VDR) promoter hypermethylation and underexpression were reported in adrenoc
Autor:
Ana Carolina, Bueno, Rui M P, da Silva, Mônica F, Stecchini, Junier, Marrero-Gutiérrez, Danillo C, de Almeida E Silva, Izilda, Cardinalli, Carlos Alberto, Scrideli, Thais, Junqueira, Carlos A F, Molina, Fernando Silva, Ramalho, Silvio, Tucci, Fernanda Borchers, Coeli-Lacchini, Ayrton Custodio, Moreira, Leandra N Z, Ramalho, Silvia, Brandalise, José Andres, Yunes, Margaret, de Castro, Ricardo Zorzetto Nicoliello, Vêncio, Sonir R R, Antonini
Publikováno v:
Endocrine-Related Cancer.
Children diagnosed with adrenocortical tumors (pACT) have variable outcomes and, to date, the disease lacks robust prognostic biomarkers. The prognostic potential of tumor methylation has been demonstrated in several cancers. We aimed to evaluate the
Autor:
Ana Carolina Bueno, Candy Bellido More, Junier Marrero-Gutiérrez, Danillo C. de Almeida e Silva, Leticia Ferro Leal, Ana Paula Montaldi, Fernando Silva Ramalho, Ricardo Zorzetto Nicoliello Vêncio, Margaret de Castro, Sonir Roberto R. Antonini
Publikováno v:
Molecular and Cellular Endocrinology. 558:111757
To evaluate the therapeutic potential of vitamin D receptor (VDR) signaling in adrenocortical carcinoma (ACC) cells.We evaluated VDR's methylation pattern in H295R ACC cells, and investigated the effects of calcitriol and seocalcitol treatments on ad
Autor:
Rui M.P. da Silva-Júnior, Ricardo Z. N. Vêncio, Izilda Aparecida Cardinalli, Fernando Silva Ramalho, Sonir Roberto Rauber Antonini, Fernanda Borchers Coeli-Lacchini, Margaret de Castro, Ayrton Custódio Moreira, Carlos Augusto Fernandes Molina, Carlos Alberto Scrideli, Silvio Tucci, José Andrés Yunes, Leandra Naira Zambelli Ramalho, Junier Marrero Gutiérrez, Ana Carolina Bueno, Silvia Regina Brandalise, Monica F Stecchini
Publikováno v:
Journal of the Endocrine Society. 5:A99-A100
Pediatric adrenocortical tumors (pACTs) display complex genomic background and lack robust prognostic biomarkers. However, pACT methylation profiling was recently associated with patient prognosis. In order to evaluate whether tumor DNA methylation i
Autor:
Alexis Acosta-Maspons, Laura Sánchez-Baldoquín, Tirso Pons, Edgar Sepúlveda-García, Lien González, Junier Marrero-Gutiérrez, Mario Rocha-Sosa
Publikováno v:
Planta. 239(1)
Metacaspases are cysteine proteases present in plants, fungi, prokaryotes, and early branching eukaryotes, although a detailed description of their cellular function remains unclear. Currently, three-dimensional (3D) structures are only available for