Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Junichiro Yuda"'
Autor:
Takafumi Tsushima, Nobue Sato, Yong‐Mei Guo, Hirotaka Nakamura, Kodai Kunisada, Song‐Gi Chi, Kenta Akie, Yuki Takahashi, Saki Nakamura, Kaoru Shimada, Genichiro Ishii, Yosuke Minami, Junichiro Yuda
Publikováno v:
eJHaem, Vol 5, Iss 3, Pp 642-645 (2024)
Externí odkaz:
https://doaj.org/article/f1890cd31aac44ff9522187493b7490c
Autor:
Junichiro Yuda, Christine Will, Darren C. Phillips, Linu Abraham, Cory Alvey, Abraham Avigdor, Wayne Buck, Lauren Besenhofer, Erwin Boghaert, Dong Cheng, Dan Cojocari, Kelly Doyle, T. Matthew Hansen, Kevin Huang, Eric F. Johnson, Andrew S. Judd, Russell A. Judge, John C. Kalvass, Aaron Kunzer, Lloyd T. Lam, Rachel Li, Ruth L. Martin, Anthony Mastracchio, Mike Mitten, Adam Petrich, Jin Wang, James E. Ward, Haichao Zhang, Xilu Wang, Johannes E. Wolff, Katherine M. Bell-McGuinn, Andrew J. Souers
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-14 (2023)
Abstract Background MCL-1 is a prosurvival B-cell lymphoma 2 family protein that plays a critical role in tumor maintenance and survival and can act as a resistance factor to multiple anticancer therapies. Herein, we describe the generation and chara
Externí odkaz:
https://doaj.org/article/a09a2953c50e4da8ad9915dfa149ffac
Autor:
Junichiro Yuda, Noriko Doki, Hiroshi Matsuoka, Takafumi Yokota, Akihiro Tomita, Naoto Takahashi, Itaru Matsumura, Kohmei Kubo, Tatsunori Goto, Keita Kirito, Akio Maki, Makoto Aoki, Alex Allepuz, Yosuke Minami
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 2990-2998 (2023)
Abstract Asciminib, a first‐in‐class, allosteric inhibitor of BCR‐ABL1 that acts by STAMP (Specifically Targeting the ABL Myristoyl Pocket), is a novel therapeutic option for patients with chronic myeloid leukemia (CML). In the global, phase 3,
Externí odkaz:
https://doaj.org/article/f3495850c1564a0f97780c72bafe4f5e
Autor:
Firas El Chaer, Lindsay Rein, Kazuya Shimoda, Junichiro Yuda, Tamanna Haque, James Mccloskey, Akiyoshi Takami, Masafumi Fukaya, Shuichi Shirane, Sujan Kabir, Jian Mei, Zhonggai LI, Mark Wade, Claudia Lebedinsky, Raajit K Rampal
Publikováno v:
HemaSphere, Vol 7, p e42358df (2023)
Externí odkaz:
https://doaj.org/article/ef0764327e2144cb9246525a9d8831ba
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)
Abstract Background The outcomes of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) can improve with allogeneic hematopoietic stem cell transplantation (HSCT) during the first complete remission after treatment with a tyrosi
Externí odkaz:
https://doaj.org/article/597cbb906d174e52b7970f3b4728ed99
Autor:
Daisuke Ikeda, SungGi Chi, Satoshi Uchiyama, Hirotaka Nakamura, Yong-Mei Guo, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5950 (2022)
The European LeukemiaNet (ELN) criteria define the adverse genetic factors of acute myeloid leukemia (AML). AML with adverse genetic factors uniformly shows resistance to standard chemotherapy and is associated with poor prognosis. Here, we focus on
Externí odkaz:
https://doaj.org/article/eed984e3ea8e462c801c8ffae5bdd3a1
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1944 (2021)
Several immune checkpoint molecules and immune targets in leukemic cells have been investigated. Recent studies have suggested the potential clinical benefits of immuno-oncology (IO) therapy against acute myeloid leukemia (AML), especially targeting
Externí odkaz:
https://doaj.org/article/978e16f782c141eda769df0858a6c1ac
Autor:
Stephen K. Tahir, Emiliano Calvo, Benedito A. Carneiro, Junichiro Yuda, Aditya Shreenivas, Mojca Jongen-Lavrencic, Eelke Gort, Kenichi Ishizawa, Daniel Morillo, Carla Biesdorf, Morey Smith, Dong Cheng, Monica Motwani, David Sharon, Tamar Uziel, Dimple A. Modi, Fritz G. Buchanan, Susan Morgan-Lappe, Bruno C. Medeiros, Darren C. Phillips
Publikováno v:
Blood, 141(17), 2114-2126. American Society of Hematology
Activation of apoptosis in malignant cells is an established strategy for controlling cancer and is potentially curative. To assess the impact of concurrently inducing the extrinsic and intrinsic apoptosis-signaling pathways in acute myeloid leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9298281c9a9769a2760e6484a88646b4
https://doi.org/10.1182/blood.2022017333
https://doi.org/10.1182/blood.2022017333
Autor:
Fumiaki Jinnouchi, Masayasu Hayashi, Katsuto Takenaka, Koji Kato, Takuya Nunomura, Shuichiro Takashima, Koichi Akashi, Jun Odawara, Takuji Yamauchi, Takahiro Shima, Goichi Yoshimoto, Junichiro Yuda, Toshihiro Miyamoto, Yasuo Mori, Kenjiro Kamezaki, Ayano Yurino
Publikováno v:
International Journal of Hematology. 115:96-106
Post-transplant cytomegalovirus (CMV) disease can be almost completely avoided by current infection control procedures. However, CMV reactivation occurs in more than half of patients, and some patients can develop clinically resistant CMV infections.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef079e583b161474ccbf12b28d29d931
https://doi.org/10.1007/s12185-021-03218-3
https://doi.org/10.1007/s12185-021-03218-3
Autor:
Kota Itahashi, Takuma Irie, Junichiro Yuda, Shogo Kumagai, Tokiyoshi Tanegashima, Yi-Tzu Lin, Sho Watanabe, Yasushi Goto, Jun Suzuki, Keiju Aokage, Masahiro Tsuboi, Yosuke Minami, Genichiro Ishii, Yuichiro Ohe, Wataru Ise, Tomohiro Kurosaki, Yutaka Suzuki, Shohei Koyama, Hiroyoshi Nishikawa
Publikováno v:
Science Immunology. 7
Regulatory T (T reg ) cells suppress effective antitumor immunity in tumor-bearing hosts, thereby becoming promising targets in cancer immunotherapy. Despite the importance of T reg cells in tumor immunity, little is known about their differentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4219696ac18a657b56b84ce301227a24
https://doi.org/10.1126/sciimmunol.abk0957
https://doi.org/10.1126/sciimmunol.abk0957