Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Junichi Yokotani"'
Autor:
Yukihiko Aikawa, Tadakazu Takakura, Keiichi Tsuchida, Shuichi Hirono, Hisaaki Chaki, Hiroaki Gouda, Shunichi Shiozawa, Junichi Yokotani
Publikováno v:
Journal of Medicinal Chemistry. 47:4239-4246
The transcription factor activator protein-1 (AP-1) is an attractive target for the treatment of immunoinflammatory diseases, such as rheumatoid arthritis. Using the three-dimensional (3D) X-ray crystallographic structure of the DNA-bound basic regio
Autor:
Yoichi MATSUNAGA, Nobuhiro SAITO, Akihiro FUJII, Junichi YOKOTANI, Tadakazu TAKAKURA, Tomoaki NISHIMURA, Hiroyuki ESAKI, Tatsuo YAMADA
Publikováno v:
Biochemical Journal. 361:547-556
In the present study we identified the epitopes of antibodies against amyloid β-(1–42)-peptide (Aβ1–42): 4G8 reacted with peptides corresponding to residues 17–21, 6F/3D reacted with peptides corresponding to residues 9–14, and anti 5-10 re
Publikováno v:
Chemical and Pharmaceutical Bulletin. 44:1326-1331
Human C-type natriuretic peptide 22 (hCNP22), the third member of the natriuretic peptide family, was efficiently synthesized by Fmoc-based peptide chain construction on a 2-chlorotrityl (Clt) resin, followed by deprotection using tetrafluoroboric ac
Autor:
Keiichi, Tsuchida, Hisaaki, Chaki, Tadakazu, Takakura, Junichi, Yokotani, Yukihiko, Aikawa, Shunichi, Shiozawa, Hiroaki, Gouda, Shuichi, Hirono
Publikováno v:
Journal of medicinal chemistry. 47(17)
The transcription factor activator protein-1 (AP-1) is an attractive target for the treatment of immunoinflammatory diseases, such as rheumatoid arthritis. Using the three-dimensional (3D) X-ray crystallographic structure of the DNA-bound basic regio
Autor:
Tatsuo Yamada, Yoichi Matsunaga, Junichi Yokotani, Aradhana Awasthi, Tadakazu Takakura, Akihiro Fujii
Publikováno v:
Regulatory peptides. 120(1-3)
Insoluble Abeta1-42 is the main component of the amyloid plaque. We have previously demonstrated that exposure to low pH can confer the molten globule state on soluble Abeta1-42 in vitro [Biochem. J. 361 (2000) 547] and unfolding experiments with gua