Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Junichi Mitsuda"'
Autor:
Takahiro Tsujikawa, Kazuchika Ohno, Kei-ichi Morita, Sumiyo Saburi, Junichi Mitsuda, Kanako Yoshimura, Alisa Kimura, Hiroki Morimoto, Hiroshi Ogi, Saya Shibata, Takumi Akashi, Morito Kurata, Issei Imoto, Yasushi Shimizu, Satoshi Kano, Akihito Watanabe, Tomoko Yamazaki, Yukinori Asada, Ryuichi Hayashi, Yuki Saito, Hiroyuki Ozawa, Kiyoaki Tsukahara, Nobuhiko Oridate, Daisuke Sano, Arata Horii, Yushi Ueki, Takashi Maruo, Nobuaki Mukoyama, Nobuhiro Hanai, Takahito Fukusumi, Hiroshi Iwai, Takuo Fujisawa, Takashi Fujii, Ken-ichi Nibu, Shigemichi Iwae, Tsutomu Ueda, Nobuyuki Chikuie, Ryuji Yasumatsu, Mioko Matsuo, Hirohito Umeno, Takeharu Ono, Muneyuki Masuda, Satoshi Toh, Kyoko Itoh, Shigeru Hirano, Takahiro Asakage
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIn view of improving biomarkers predicting the efficacy of immunotherapy for head and neck squamous cell carcinoma (R/M HNSCC), this multicenter retrospective study aimed to identify clinical, tumor microenvironmental, and genomic factors t
Externí odkaz:
https://doaj.org/article/b5c525023e134051b6b1b1fa136b47f3
Autor:
Hiroki Ishii, Takahiro Tsujikawa, Naoki Oishi, Arisa Kinouchi, Kaname Sakamoto, Junichi Mitsuda, Hiroshi Ogi, Kyoko Itoh, Tetsuo Kondo, Shigeru Hirano, Daiju Sakurai
Publikováno v:
Clinical Case Reports, Vol 10, Iss 7, Pp n/a-n/a (2022)
Abstract Metastatic intrathyroid thymic carcinoma (ITTC) is a rare cancer with no effective drugs for controlling. This case report has shown genomic and immune microenvironment profiles in metastatic ITTC and emphasized an immunosuppression via a PD
Externí odkaz:
https://doaj.org/article/d373a705f9384055b200dd210b07c07e
Autor:
Kanako Yoshimura, Takahiro Tsujikawa, Junichi Mitsuda, Hiroshi Ogi, Sumiyo Saburi, Gaku Ohmura, Akihito Arai, Saya Shibata, Guillaume Thibault, Young Hwan Chang, Daniel R. Clayburgh, Satoru Yasukawa, Aya Miyagawa-Hayashino, Eiichi Konishi, Kyoko Itoh, Lisa M. Coussens, Shigeru Hirano
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundFunctional interactions between immune cells and neoplastic cells in the tumor immune microenvironment have been actively pursued for both biomarker discovery for patient stratification, as well as therapeutic anti-cancer targets to improve
Externí odkaz:
https://doaj.org/article/0dd2889cd18447c9a68d337c9bbb7a5b
Autor:
Junichi Mitsuda, Takahiro Tsujikawa, Kanako Yoshimura, Sumiyo Saburi, Masaho Suetsugu, Kayo Kitamoto, Mari Takenaka, Gaku Ohmura, Akihito Arai, Hiroshi Ogi, Kyoko Itoh, Shigeru Hirano
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Recent advances made in treatment for head and neck squamous cell carcinoma (HNSCC) highlight the need for new prediction tools to guide therapeutic strategies. In this study, we aimed to develop a HNSCC-targeting multiplex immunohistochemical (IHC)
Externí odkaz:
https://doaj.org/article/928af1fba9714bfdbf99965f04d7cb3b
Autor:
Takahiro Tsujikawa, Alisa Kimura, Hiroki Morimoto, Sumiyo Saburi, Junichi Mitsuda, Kanako Yoshimura, Daichi Mori, Gaku Ohmura, Shigeyuki Mukudai, Yoichiro Sugiyama, Shigeru Hirano
Publikováno v:
JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY. 32:117-120
Autor:
Aoi Ikeda, Youichirou Sugiyama, Junichi Mitsuda, Akihito Arai, Hiroki Morimoto, Arisa Kimura, Kanako Yoshimura, Sumiyo Saburi, Gaku Oomura, Takahiro Tsujikawa, Shigeru Hirano
Publikováno v:
JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY. 32:197-202
Autor:
Alisa Kimura, Takahiro Tsujikawa, Junichi Mitsuda, Aya Miyagawa-Hayashino, Hiroki Morimoto, Sumiyo Saburi, Kanako Yoshimura, Gaku Ohmura, Sigeyuki Mukudai, Hikaru Nagao, Yoichiro Sugiyama, Hiroshi Ogi, Saya Shibata, Eiichi Konishi, Kyoko Itoh, Shigeru Hirano
Publikováno v:
Cancer Research. 83:5172-5172
Understanding longitudinal changes of tumor-immune microenvironment during chemo/targeted therapies contributes to the development of optimized combinations of immunotherapy with chemotherapy and targeted therapy for patients with head and neck squam
Autor:
Hiroki Morimoto, Takahiro Tsujikawa, Aya Miyagawa-Hayashino, Alisa Kimura, Sumiyo Saburi, Junichi Mitsuda, Kanako Yoshimura, Gaku Ohmura, Shigeyuki Mukudai, Hikaru Nagao, Yoichiro Sugiyama, Shibata Saya, Hiroshi Ogi, Eiichi Konishi, Kyoko Itoh, Shigeru Hirano
Publikováno v:
Cancer Research. 83:4453-4453
Neutrophil-to-lymphocyte ratio (NLR) in peripheral blood is an emerging biomarker candidate of immunotherapy in a wide range of cancers. However, little is known about the potential relationships between the tumor immune microenvironment and systemic
Autor:
Akihito Arai, Junichi Mitsuda, Rena Takabatake, Keiko Hashimoto, Takahiro Tsujikawa, Koichi Yoshizawa, Kanako Yoshimura, Yoichiro Sugiyama, Sumiyo Saburi, Mari Takenaka, Shigeru Hirano
Publikováno v:
JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY. 30:79-85
Autor:
Takahiro Tsujikawa, Kazuchika Ohno, Sumiyo Saburi, Junichi Mitsuda, Kanako Yoshimura, Alisa Kimura, Hiroki Morimoto, Gaku Ohmura, Akihito Arai, Hiroshi Ogi, Saya Shibata, Yosuke Ariizumi, Akihisa Tasaki, Ryosuke Takahashi, Yumiko Tateishi, Hiroaki Kawabe, Sadakatsu Ikeda, Kei-ichi Morita, Tatsuhiko Tsunoda, Takumi Akashi, Morito Kurata, Issei Imoto, Yasushi Shimizu, Akihito Watanabe, Yukinori Asada, Ryuichi Hayashi, Yuki Saito, Hiroyuki Ozawa, Kiyoaki Tsukahara, Nobuhiko Oridate, Arata Horii, Takashi Maruo, Nobuhiro Hanai, Hidenori Inohara, Hiroshi Iwai, Takashi Fujii, Ken-ichi Nibu, Shigemichi Iwae, Tsutomu Ueda, Ryuji Yasumatsu, Hirohito Umeno, Muneyuki Masuda, Kyoko Itoh, Shigeru Hirano, Takahiro Asakage
Publikováno v:
Cancer Research. 82:5210-5210
Background: Biomarkers predicting therapeutic response to immunotherapy have been widely explored via monitoring the liquid and tissue-derived components. Increasing treatment options for recurrent/metastatic head and neck squamous cell carcinoma (R/