Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Junichi Iwakiri"'
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-19 (2020)
Abstract Background Analysis of secondary structures is essential for understanding the functions of RNAs. Because RNA molecules thermally fluctuate, it is necessary to analyze the probability distributions of their secondary structures. Existing met
Externí odkaz:
https://doaj.org/article/73f1f209cd4b4e1eb81137275f13e437
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 1, p e1009804 (2022)
Nonstructural protein 1 (nsp1) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a 180-residue protein that blocks translation of host mRNAs in SARS-CoV-2-infected cells. Although it is known that SARS-CoV-2's own RNA evades nsp1's h
Externí odkaz:
https://doaj.org/article/722c8425d04442239c1f7f3c8d1318dd
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S3, Pp 15-24 (2019)
Abstract Background Recently, next-generation sequencing techniques have been applied for the detection of RNA secondary structures, which is referred to as high-throughput RNA structural (HTS) analyses, and many different protocols have been used to
Externí odkaz:
https://doaj.org/article/9e593f3ccb9640669f50d86d6b815717
Publikováno v:
BMC Bioinformatics, Vol 19, Iss S1, Pp 85-95 (2018)
Abstract Background It is known that functional RNAs often switch their functions by forming different secondary structures. Popular tools for RNA secondary structures prediction, however, predict the single ‘best’ structures, and do not produce
Externí odkaz:
https://doaj.org/article/931a84668fd64b70be84d3a263748634
Publikováno v:
Biology Direct, Vol 12, Iss 1, Pp 1-8 (2017)
Abstract Long noncoding RNAs (lncRNAs) play a key role in normal tissue differentiation and cancer development through their tissue-specific expression in the human transcriptome. Recent investigations of macromolecular interactions have shown that t
Externí odkaz:
https://doaj.org/article/bc1c05d4ae82480dac6f416bd241cc48
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Long non-coding RNAs (lncRNAs) play critical roles in various biological processes, but the function of the majority of lncRNAs is still unclear. One approach for estimating a function of a lncRNA is the identification of its interaction target becau
Externí odkaz:
https://doaj.org/article/7cae0b81dc6a475cb53f7edf0b8f45da
Autor:
Junichi Iwakiri, Kumiko Tanaka, Takeshi Chujo, Hiro Takakuwa, Tomohiro Yamazaki, Goro Terai, Kiyoshi Asai, Tetsuro Hirose
Publikováno v:
RNA. 29:170-177
The mammalian cell nucleus contains dozens of membrane-less nuclear bodies that play significant roles in various aspects of gene expression. Several nuclear bodies are nucleated by specific architectural noncoding RNAs (arcRNAs) acting as structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b103ac02cb94595812aa98da3747700e
https://doi.org/10.1261/rna.079469.122
https://doi.org/10.1261/rna.079469.122
Autor:
Satoru Shinriki, Mayumi Hirayama, Akiko Nagamachi, Akihiko Yokoyama, Takeshi Kawamura, Akinori Kanai, Hidehiko Kawai, Junichi Iwakiri, Rin Liu, Manabu Maeshiro, Saruul Tungalag, Masayoshi Tasaki, Mitsuharu Ueda, Kazuhito Tomizawa, Naoyuki Kataoka, Takashi Ideue, Yutaka Suzuki, Kiyoshi Asai, Tokio Tani, Toshiya Inaba, Hirotaka Matsui
Publikováno v:
Leukemia. 36:2605-2620
Myeloid malignancies with DDX41 mutations are often associated with bone marrow failure and cytopenia before overt disease manifestation. However, the mechanisms underlying these specific conditions remain elusive. Here, we demonstrate that loss of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788aa1190ebda86839e97eca377f1e1b
https://doi.org/10.1038/s41375-022-01708-9
https://doi.org/10.1038/s41375-022-01708-9
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627679
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5891fa280ef4c8f14cfc4f6b0a620501
https://doi.org/10.1007/978-1-0716-2768-6_17
https://doi.org/10.1007/978-1-0716-2768-6_17
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627679
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4588d21241d5b479059f7815e27ca2f
https://doi.org/10.1007/978-1-0716-2768-6_11
https://doi.org/10.1007/978-1-0716-2768-6_11