Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Junichi Hachisuka"'
Autor:
Charles Warwick, Joseph Salsovic, Junichi Hachisuka, Kelly M. Smith, Tayler D. Sheahan, Haichao Chen, James Ibinson, H. Richard Koerber, Sarah E. Ross
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Altered mechanosensation by application of capsaicin to the skin is thought to be spinally mediated. Here, the authors use Ca2+ imaging in spinal neurons and develop a cell profiling approach to identify populations involved in central sensitization.
Externí odkaz:
https://doaj.org/article/80ac351424da470497cb041b61dfcedc
Autor:
Junichi Hachisuka, Kyle M Baumbauer, Yu Omori, Lindsey M Snyder, H Richard Koerber, Sarah E Ross
Publikováno v:
eLife, Vol 5 (2016)
The somatosensory input that gives rise to the perceptions of pain, itch, cold and heat are initially integrated in the superficial dorsal horn of the spinal cord. Here, we describe a new approach to investigate these neural circuits in mouse. This s
Externí odkaz:
https://doaj.org/article/170e130e531246b294a1ba03662b4e5c
Publikováno v:
Case Reports in Dermatology, Vol 3, Iss 2, Pp 130-136 (2011)
Epidermal growth factor receptor (EGFR) inhibitors are increasingly used for cancer treatment, but commonly carry dermatologic side effects. Periungual inflammation is a particularly painful condition that additionally worsens quality of life. In thi
Externí odkaz:
https://doaj.org/article/5ca20114e1ff4e88be86e03f2e9c5c8d
Autor:
Kyle M Baumbauer, Jennifer J DeBerry, Peter C Adelman, Richard H Miller, Junichi Hachisuka, Kuan Hsien Lee, Sarah E Ross, H Richard Koerber, Brian M Davis, Kathryn M Albers
Publikováno v:
eLife, Vol 4 (2015)
How thermal, mechanical and chemical stimuli applied to the skin are transduced into signals transmitted by peripheral neurons to the CNS is an area of intense study. Several studies indicate that transduction mechanisms are intrinsic to cutaneous ne
Externí odkaz:
https://doaj.org/article/953da3fcf9af416198b70bda3b667ca0
Autor:
Junichi Hachisuka
Publikováno v:
The Nishinihon Journal of Dermatology. 85:135-136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3654858cd1b43d95a17bb9715480bcf
https://doi.org/10.2336/nishinihonhifu.85.135
https://doi.org/10.2336/nishinihonhifu.85.135
Autor:
Tayler D. Sheahan, Sarah E. Ross, Margaret C. Wright, Junichi Hachisuka, Kyle M. Baumbauer, Kuan H. Lee, Colleen Cassidy, Peter C. Adelman, Charles A. Warwick, H. Richard Koerber, Kelly M. Smith
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. This study suggests that activation of nonpeptidergic afferents becomes aversive after spared nerve injury through the recruitment of a normally silent polysynaptic pathway.
Most cutaneous C
Most cutaneous C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a785421dd7d694d6e42394c8f2a76c9
http://europepmc.org/articles/PMC8206522
http://europepmc.org/articles/PMC8206522
Publikováno v:
Science Translational Medicine. 13
Morphine-induced itch is a very common and debilitating side effect that occurs in laboring women who receive epidural analgesia and in patients who receive spinal morphine for relief of perioperative pain. Although antihistamines are still widely pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ba712000538eda04aac945efc7ce40
https://doi.org/10.1126/scitranslmed.abc3774
https://doi.org/10.1126/scitranslmed.abc3774
Publikováno v:
Pain. 159:1484-1493
Wind-up is a frequency-dependent increase in the response of spinal cord neurons, which is thought to underlie temporal summation of nociceptive input. However, whether spinoparabrachial neurons, which likely contribute to the affective component of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99018b9c96954a73c5fcf1af00e389cc
https://doi.org/10.1097/j.pain.0000000000001229
https://doi.org/10.1097/j.pain.0000000000001229
Publikováno v:
Pain. 159:603-609
Neuropathic itch is a pathological condition that is due to damage within the nervous system. This type of itch can be severe and unrelenting, which has a very negative impact on quality of life. Neuropathic itch is more common than generally appreci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c15481801286cd26206f7c539cda4cb
https://doi.org/10.1097/j.pain.0000000000001141
https://doi.org/10.1097/j.pain.0000000000001141
Publikováno v:
Pain. 161(1)
Spinal projection neurons are a major pathway through which somatic stimuli are conveyed to the brain. However, the manner in which this information is coded is poorly understood. Here, we report the identification of a modality-selective spinoparabr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c76a2bb1c6b5b533d6d2dda798667e
https://pubmed.ncbi.nlm.nih.gov/31577643
https://pubmed.ncbi.nlm.nih.gov/31577643