Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Junichi, Omura"'
Publikováno v:
Pulmonary Therapy, Vol 10, Iss 3, Pp 297-313 (2024)
Abstract Introduction The pathogenesis and clinical profiles of patients with pulmonary hypertension (PH) associated with interstitial lung disease (ILD-PH) are poorly understood. Whether and to what extent pulmonary arterial hypertension (PAH)-speci
Externí odkaz:
https://doaj.org/article/36828f3a71ff497fa89abaf5c104080d
Publikováno v:
Pulmonary Therapy, Vol 10, Iss 1, Pp 21-49 (2023)
Abstract Introduction Pulmonary hypertension (PH) is often complicated by chronic lung diseases (CLDs) such as chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD). Differentiating between PH associated with CLD (group 3 P
Externí odkaz:
https://doaj.org/article/cd649a56162d4a5a89fe3aa4bbf8e49d
Autor:
Junichi Omura, Yogeshwar Makanji, Nobuhiro Tanabe, Dae Young Yu, Jin Yu Tan, Sooyeol Lim, Mahsa H. Kouhkamari, Jeremy Casorso, David Bin-Chia Wu, Paul Bloomfield
Publikováno v:
Pulmonary Therapy, Vol 9, Iss 4, Pp 511-526 (2023)
Abstract Introduction Real-world data on the comparative effectiveness of endothelin receptor antagonists (ERAs; macitentan, bosentan, ambrisentan) for pulmonary arterial hypertension (PAH), particularly in Asian countries, are scarce. We evaluated t
Externí odkaz:
https://doaj.org/article/84065d105090462abee8d697d08b7e49
Publikováno v:
JGH Open, Vol 6, Iss 11, Pp 763-773 (2022)
Abstract Background and Aim Portopulmonary hypertension (PoPH) is a complication associated with portal hypertension. Since the epidemiological study in Japan was limited, this study aimed to investigate the characteristics, treatment patterns, and p
Externí odkaz:
https://doaj.org/article/6cdb067168774334ab65277eaaf2c9cd
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 3, Pp n/a-n/a (2023)
Abstract Pulmonary arterial hypertension (PAH) is a fatal disease that often occurs at an early age. In recent years, aggressive treatment with multiple drugs from the early‐stage diagnosis is expected to improve the prognosis. Indeed, a high rate
Externí odkaz:
https://doaj.org/article/baecf2445f6547ee9bd3b418f2361d88
Publikováno v:
Pulmonary Therapy, Vol 10, Iss 1, Pp 51-52 (2023)
Externí odkaz:
https://doaj.org/article/42ff2b6ae0f443edb14123721af5097a
Autor:
Lorna E. Latimer, Marieke Duiverman, Mahmoud I. Abdel-Aziz, Gulser Caliskan, Sara M. Mensink-Bout, Alberto Mendoza-Valderrey, Aurelien Justet, Junichi Omura, Srikanthan Karthi, Jana De Brandt
Publikováno v:
Breathe, Vol 15, Iss 4, Pp e143-e149 (2019)
Externí odkaz:
https://doaj.org/article/ac6860648f074f49b44325f83c33f7b9
Autor:
Tomohiro Ohtsuki, Kimio Satoh, Toru Shimizu, Shohei Ikeda, Nobuhiro Kikuchi, Taijyu Satoh, Ryo Kurosawa, Masamichi Nogi, Shinichiro Sunamura, Nobuhiro Yaoita, Junichi Omura, Tatsuo Aoki, Shunsuke Tatebe, Koichiro Sugimura, Jun Takahashi, Satoshi Miyata, Hiroaki Shimokawa
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 23 (2019)
Background Circulating proteins are exposed to vascular endothelial layer and influence their functions. Among them, adipsin is a member of the trypsin family of peptidases and is mainly secreted from adipocytes, monocytes, and macrophages, catalyzin
Externí odkaz:
https://doaj.org/article/facf05007d0043f8af15ebbce81c047b
Autor:
Tsukasa Shimauchi, Olivier Boucherat, Tetsuro Yokokawa, Yann Grobs, WenHui Wu, Mark Orcholski, Sandra Martineau, Junichi Omura, Eve Tremblay, Kana Shimauchi, Valérie Nadeau, Sandra Breuils-Bonnet, Roxane Paulin, François Potus, Steeve Provencher, Sébastien Bonnet
Publikováno v:
JACC: Basic to Translational Science. 7:384-403
The authors show that increased poly(adenosine diphosphate-ribose) polymerase 1 (PARP1) and pyruvate kinase muscle isozyme 2 (PKM2) expression is a common feature of a decompensated right ventricle in patients with pulmonary arterial hypertension and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246bb85dc13ed096d9328c3bce296223
https://doi.org/10.1016/j.jacbts.2022.01.005
https://doi.org/10.1016/j.jacbts.2022.01.005
Autor:
Junichi Omura, Sandra Breuils-Bonnet, Eve Tremblay, Alice Bourgeois, Steeve Provencher, Yann Grobs, Tsukasa Shimauchi, Geraldine Vitry, Wen-Hui Wu, Victoria Toro, Mark Orcholski, Roxane Paulin, Sandra Martineau, Valérie Nadeau, Sébastien Bonnet, Pasquale Ferraro, Charlotte Romanet, François Potus, Olivier Boucherat
Publikováno v:
Thorax. 77:247-258
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterised by exuberant tissue remodelling and associated with high unmet medical needs. Outcomes are even worse when IPF results in secondary pulmonary hypertension (PH). Imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ae239beee2050e9a91d1c3a7d936c9a
https://doi.org/10.1136/thoraxjnl-2021-217377
https://doi.org/10.1136/thoraxjnl-2021-217377