Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Junichi, Hara"'
Autor:
Pietro Giorgio Spezia, Kazunari Matsudaira, Fabio Filippini, Takako Miyamura, Keiko Okada, Yoshiro Nagao, Takafumi Ishida, Tetsuya Sano, Mauro Pistello, Fabrizio Maggi, Junichi Hara
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Cause of Kawasaki disease (KD) is unknown. KD is often resistant to treatment with intravenous immunoglobulin (IVIG). Sano’s score, which is derived from total bilirubin (TBIL), aspartate aminotransferase (AST) and C-reactive protein (CRP)
Externí odkaz:
https://doaj.org/article/48ef770ec1bd412d864579d21e748c14
Autor:
Ryo Morita, Ritsuko Kubota-Koketsu, Xiuyuan Lu, Tadahiro Sasaki, Emi E. Nakayama, Yu-chen Liu, Daisuke Okuzaki, Daisuke Motooka, James Badger Wing, Yasunori Fujikawa, Yuji Ichida, Kiyoko Amo, Tetsushi Goto, Junichi Hara, Michinori Shirano, Sho Yamasaki, Tatsuo Shioda
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106685- (2023)
Summary: A 25-year-old patient with a primary immunodeficiency lacking immunoglobulin production experienced a relapse after a 239-day period of persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Viral genetic sequenci
Externí odkaz:
https://doaj.org/article/f0e08f94d7854578b413062f38f95992
Autor:
Akie Kobayashi, Ryusei Ohtaka, Tsutomu Toki, Junichi Hara, Hideki Muramatsu, Rika Kanezaki, Yuka Takahashi, Tomohiko Sato, Takuya Kamio, Ko Kudo, Shinya Sasaki, Taro Yoshida, Taiju Utsugisawa, Hitoshi Kanno, Kenichi Yoshida, Yasuhito Nannya, Yoshiyuki Takahashi, Seiji Kojima, Satoru Miyano, Seishi Ogawa, Kiminori Terui, Etsuro Ito
Publikováno v:
eJHaem, Vol 3, Iss 1, Pp 163-167 (2022)
Abstract Diamond‐Blackfan anaemia (DBA) shares clinical features with two recently reported sporadic cases of dyserythropoietic anaemia with a cryptic GATA1 splicing mutation (c.871‐24 C>T). We hypothesized that some patients clinically diagnosed
Externí odkaz:
https://doaj.org/article/ab23682fb6af434fa7f986a01af0fcf7
Autor:
Yutaka Fukaya, Toshimi Kimura, Yukihiro Hamada, Kenichi Yoshimura, Hiroaki Hiraga, Yuki Yuza, Atsushi Ogawa, Junichi Hara, Katsuyoshi Koh, Atsushi Kikuta, Yuhki Koga, Hiroshi Kawamoto
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionGlucarpidase (CPG2) reduces the lethal toxicity of methotrexate (MTX) by rapid degradation.MethodsIn this study, a CPG2 population pharmacokinetics (popPK) analysis in healthy volunteers (phase 1 study) and a popPK-pharmacodynamics (popPK
Externí odkaz:
https://doaj.org/article/292f626a73b4408999f2f71b86f39e93
Autor:
Kazuki Tanimura, Kai Yamasaki, Yuki Okuhiro, Kota Hira, Chika Nitani, Keiko Okada, Hiroyuki Fujisaki, Kana Matsumoto, Junichi Hara
Publikováno v:
Case Reports in Oncology, Vol 14, Iss 1, Pp 24-28 (2021)
Ponatinib is a third-generation tyrosine kinase inhibitor (TKI) reported to show a higher efficacy for adult Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) than other TKIs. However, few studies describe ponatinib for pediatric
Externí odkaz:
https://doaj.org/article/2831b36850924622a7819ce0abc83cf9
Autor:
Junichi, Hara, Kimikazu, Matsumoto, Naoko, Maeda, Mariko, Takahara-Matsubara, Saori, Sugimoto, Hiroaki, Goto
Publikováno v:
Bone Marrow Transplantation. 58:123-128
Among pediatric malignancies, solid tumors, particularly within the central nervous system (CNS), are common. Thiotepa, a myeloablative, high-dose chemotherapeutic (HDT) treatment administered prior to autologous hematopoietic stem cell transplantati
Autor:
Naoyuki Miyagawa, Hiroaki Goto, Atsushi Ogawa, Atsushi Kikuta, Yoshiyuki Kosaka, Masahiro Sekimizu, Daisuke Tomizawa, Hidemi Toyoda, Hidefumi Hiramatsu, Junichi Hara, Shinji Mochizuki, Hideki Nakayama, Kenichi Yoshimura, Yuka Iijima-Yamashita, Masashi Sanada, Chitose Ogawa
Publikováno v:
International Journal of Hematology.
Autor:
Chihaya Imai, Atsushi Sato, Mitsuteru Hiwatari, Yasuto Shimomura, Toshinori Hori, Souichi Suenobu, Toshihiko Imamura, Junichi Hara, Daisuke Hasegawa, Hiroyuki Takahashi, Kunihiko Moriya, Saori Katayama, Daisuke Tomizawa, Hiroshi Moritake, Takashi Taga, Keizo Horibe, Katsuyoshi Koh, Atsushi Manabe, Yasuhiro Okamoto
Publikováno v:
International Journal of Hematology.
Autor:
Hisashi Ishida, Toshihiko Imamura, Yasuhisa Tatebe, Takashi Ishihara, Kimiyoshi Sakaguchi, Souichi Suenobu, Atsushi Sato, Yoshiko Hashii, Takao Deguchi, Yoshihiro Takahashi, Daiichiro Hasegawa, Takako Miyamura, Akihiro Iguchi, Koji Kato, Akiko Saito‐Moriya, Junichi Hara, Keizo Horibe
Publikováno v:
British Journal of Haematology.
Autor:
Keiji Tasaka, Hiroo Ueno, Kai Yamasaki, Takahiro Okuno, Tomoya Isobe, Shunsuke Kimura, Katsutsugu Umeda, Junichi Hara, Seishi Ogawa, Junko Takita
Publikováno v:
Cancer Science. 113(4):1535-1541
Neuroblastoma (NB) and pheochromocytoma (PCC) are derived from neural crest cells (NCCs); however, composite tumors with NB and PCC are rare, and their underlying molecular mechanisms remain unknown. To address this issue, we performed exome and tran