Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Junia Dushime"'
Autor:
Oliver Mikse, Tahirih L. Lamothe, Lisa M Olson, Nidhi Jain, Jennifer L. Proctor, Ryan Knihtila, Sean McDonough, John C. Davis, Anthony E. Boitano, Rahul Palchaudhuri, Michael P. Cooke, Ganapathy N. Sarma, Bradley R. Pearse, Prashant raj Bhattarai, Leanne Lanieri, Junia Dushime, Kellie Latimer
Publikováno v:
Transplantation and Cellular Therapy. 27:S49-S50
Autor:
Ryan Knihtila, Michael P. Cooke, Tahirih L. Lamothe, Leanne Lanieri, Sean McDonough, Anthony E. Boitano, Prashant raj Bhattarai, John C. Davis, Rahul Palchaudhuri, Junia Dushime, Jennifer L. Proctor, Oliver Miske, Nidhi Jain, Ganapathy N. Sarma, Bradley R. Pearse, Kellie Latimer
Publikováno v:
Blood. 136:47-48
Hematopoietic stem cell transplant (HSCT) can be a highly effective, and often curative, treatment for patients with AML. At present, myeloablative conditioning (MAC) regimens are associated with severe acute and long-term toxicities. A subset of tra
Autor:
Renpeng Liu, Lintao Wang, Thomas Ryll, Alexandru C. Lazar, Xuan Chen, Megan Bogalhas, Junia Dushime
Publikováno v:
mAbs. 9:490-497
Antibody-drug conjugates (ADCs) are promising biotherapeutic agents for the treatment of cancer. The careful monitoring of critical quality attributes is important for ADCs' development, manufacturing and production. In this work, the effect of the p
Autor:
Rahul Palchaudhuri, Junia Dushime, Jason Neale, Ganapathy N. Sarma, Bradley R. Pearse, Melissa L. Brooks, Charlotte Mcdonagh, Jennifer L. Proctor, Anthony E. Boitano, Tahirih L. Lamothe, Ryan Knihtila, Nidhi Jain, Rajiv Panwar, Qing Li, Sean McDonough, John C. Davis, Michael P. Cooke, Lena Kien, Kellie Latimer
Publikováno v:
Biology of Blood and Marrow Transplantation. 26:S35-S36
Current approaches to conditioning prior to transplant and gene therapy employ non-specific genotoxic agents that are associated with severe acute and long-term toxicities. Consequently, many transplant eligible patients either refuse transplant or r
Autor:
Anthony E. Boitano, Kellie Latimer, Rahul Palchaudhuri, Sean McDonough, Nathaniel S. Linde, Ganapathy N. Sarma, Lena Kien, Robert E. Donahue, Bradley R. Pearse, Junia Dushime, John F. Tisdale, Jennifer L. Proctor, Michael P. Cooke, Allen E. Krouse, Melissa L. Brooks, Qing Li, Aylin C. Bonifacino, Rajiv Panwar, Naoya Uchida, Pranoti Sawant, Sharon L. Hyzy, Charlotte Mcdonagh
Publikováno v:
Biology of Blood and Marrow Transplantation. 26:S6
Autologous hematopoietic stem cell transplantation (Auto-HSCT) with gene-modification represents a potential cure for multiple genetic diseases, but its broad curative potential, is limited because of morbidity/mortality from cytotoxic chemotherapy-b
Autor:
Nathaniel S. Linde, Kellie Latimer, Lena Kien, John F. Tisdale, Aylin C. Bonifacino, Qing Li, Rajiv Panwar, Naoya Uchida, Robert E. Donahue, Anthony E. Boitano, Melissa L. Brooks, Sharon L. Hyzy, Rahul Palchaudhuri, Michael P. Cooke, Sean McDonough, Ganapathy N. Sarma, Bradley R. Pearse, Junia Dushime, Charlotte Mcdonagh, Allen E. Krouse, Pranoti Sawant, Jennifer L. Proctor
Publikováno v:
Blood. 134:610-610
Autologous hematopoietic stem cell transplantation (Auto-HSCT) with gene-modification techniques represents a potential cure for multiple genetic blood diseases. Despite its broad curative potential, auto-gene modified HSCT is currently limited due t
Autor:
Rahul Palchaudhuri, Ganapathy N. Sarma, Bradley R. Pearse, Sharon L. Hyzy, Rajiv Panwar, Junia Dushime, Michael P. Cooke, Melissa L. Brooks, Hillary L. Adams, Anthony E. Boitano, Jennifer L. Proctor, Pranoti Sawant, Qing Li, Sean McDonough, Charlotte Mcdonagh, Tahirih L. Lamothe, Nidhi Jain, Lena Kien
Publikováno v:
Biology of Blood and Marrow Transplantation. 25:S29-S30
Current regimens for patient preparation, or conditioning, prior to bone marrow transplantation (BMT) limit the use of this curative procedure due to regimen-related mortality and morbidities. To address this, we developed a CD117-ADC to specifically
Autor:
Andrew D Gabros, Brad R. Pearse, Lena Kien, Geoff O Gillard, Sharon L. Hyzy, Anthony E. Boitano, Anjali Bhat, Rahul Palchaudhuri, Sean McDonough, Jennifer L. Proctor, Charlotte Mcdonagh, Junia Dushime, Ganapathy N. Sarma, Danielle Ladwig, Patrick C. Falahee, Nidhi Jain, Michael P. Cooke, Tahirih L. Lamothe, Pranoti Sawant, Hillary L. Adams, Qing Li, Sharon Aslanian, Rajiv Panwar
Publikováno v:
Biology of Blood and Marrow Transplantation. 25:S32
Introduction Bone Marrow Transplant (BMT) is a potentially curative treatment for malignant and non-malignant blood disorders. Current regimens for patient preparation, or conditioning, prior to BMT limit the use of this curative procedure due to reg
Autor:
Andrew D Gabros, Charlotte Mcdonagh, Junia Dushime, Rahul Palchaudhuri, Ganapathy N. Sarma, Bradley R. Pearse, Qing Li, Lena Kien, Sean McDonough, Hillary L. Adams, Anthony E. Boitano, Melissa L. Brooks, Jennifer L. Proctor, Danielle Ladwig, Michael P. Cooke, Sharon L. Hyzy, Rajiv Panwar, Sharon Aslanian
Publikováno v:
Biology of Blood and Marrow Transplantation. 25:S100
Allogeneic bone marrow transplant (BMT) is a potentially curative approach in patients with refractory or high-risk hematologic malignancies, like acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Current regimens for patient preparat
Autor:
Rahul Palchaudhuri, Ganapathy N. Sarma, Bradley R. Pearse, Jennifer L. Proctor, Qing Li, Lena Kien, Junia Dushime, Nathan M Kallen, Pranoti Sawant, Michael P. Cooke, Anthony E. Boitano, Sharon L. Hyzy, Rajiv Panwar, Sean McDonough, Melissa L. Brooks, Molly A McShea, Charlotte Mcdonagh, Hillary L. Adams
Publikováno v:
Blood. 132:3314-3314
Background: Genotoxic conditioning prior to allogeneic and autologous bone marrow transplantation (BMT) limits the use of these potentially curative treatments due to risks of regimen-related morbidities and mortality, including risks of organ toxici