Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Juni Palmgren"'
Autor:
Keith Humphreys, Alexander Grankvist, Monica Leu, Per Hall, Jianjun Liu, Samuli Ripatti, Karola Rehnström, Leif Groop, Lars Klareskog, Bo Ding, Henrik Grönberg, Jianfeng Xu, Nancy L Pedersen, Paul Lichtenstein, Morten Mattingsdal, Ole A Andreassen, Colm O'Dushlaine, Shaun M Purcell, Pamela Sklar, Patrick F Sullivan, Christina M Hultman, Juni Palmgren, Patrik K E Magnusson
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22547 (2011)
Patterns of genetic diversity have previously been shown to mirror geography on a global scale and within continents and individual countries. Using genome-wide SNP data on 5174 Swedes with extensive geographical coverage, we analyzed the genetic str
Externí odkaz:
https://doaj.org/article/cf12f40b551a42d5a2409e1be5738add
Autor:
Boel Brynedal, Kristina Duvefelt, Gudrun Jonasdottir, Izaura M Roos, Eva Akesson, Juni Palmgren, Jan Hillert
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e664 (2007)
A recent high-density linkage screen confirmed that the HLA complex contains the strongest genetic factor for the risk of multiple sclerosis (MS). In parallel, a linkage disequilibrium analysis using 650 single nucleotide polymorphisms (SNP) markers
Externí odkaz:
https://doaj.org/article/7c44940149cb4ae19c5b85ae6f93012e
Autor:
Kristjana Einarsdóttir, Keith Humphreys, Carine Bonnard, Juni Palmgren, Mark M Iles, Arvid Sjölander, Yuqing Li, Kee Seng Chia, Edison T Liu, Per Hall, Jianjun Liu, Sara Wedrén
Publikováno v:
PLoS Medicine, Vol 3, Iss 6, p e168 (2006)
BACKGROUND: Checkpoint kinase 2 (CHEK2) averts cancer development by promoting cell cycle arrest and activating DNA repair in genetically damaged cells. Previous investigation has established a role for the CHEK2 gene in breast cancer aetiology, but
Externí odkaz:
https://doaj.org/article/c151b726ac9b4d14a23a69df16373dd5
Autor:
Pär Sparén, Nathalie Ylitalo, Hans-Olov Adami, Joakim Dillner, Juni Palmgren, Lisen Arnheim Dahlström, Alexander Ploner, Karin Sundström
PDF file - 259K, Modeling and adjusting viral load over time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad466f0e653c33ebd067149635fdf2d5
https://doi.org/10.1158/1055-9965.22436130
https://doi.org/10.1158/1055-9965.22436130
Autor:
Kamila Czene, Henrik Grönberg, Jonas Bergh, Per Hall, Johan Lindberg, Mattias Rantalainen, Jan Frisell, Johan Hartman, Keith Humphreys, Sven Törnberg, Juni Palmgren, Camilla Cristando, Gabriela Prochazka, Johanna Holm, Linda Sofie Lindström, Nicholas P. Tobin, Daniel Klevebring, Emma Ivansson, Jingmei Li
Supplementary Table 1. List of 516 deep-sequenced cancer-related genes; Supplementary Table 2. Clinicopathological characteristics of screen-detected (n=109) versus interval breast cancers (n=111) in the validation dataset; Supplementary Table 3. Cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25117c0f6e3fd3ca085da05368f32adb
https://doi.org/10.1158/1078-0432.22466696
https://doi.org/10.1158/1078-0432.22466696
Autor:
Pär Sparén, Nathalie Ylitalo, Hans-Olov Adami, Joakim Dillner, Juni Palmgren, Lisen Arnheim Dahlström, Alexander Ploner, Karin Sundström
Background: A strong association has been shown between high viral DNA load (VL) of human papillomavirus (HPV) type 16 and risk for cervical cancer in situ (CIS). However, little data is available for the significance of VL in invasive squamous cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3103b294ff21980cbce22dda7b9621cd
https://doi.org/10.1158/1055-9965.c.6515247.v1
https://doi.org/10.1158/1055-9965.c.6515247.v1
Autor:
Kamila Czene, Henrik Grönberg, Jonas Bergh, Per Hall, Johan Lindberg, Mattias Rantalainen, Jan Frisell, Johan Hartman, Keith Humphreys, Sven Törnberg, Juni Palmgren, Camilla Cristando, Gabriela Prochazka, Johanna Holm, Linda Sofie Lindström, Nicholas P. Tobin, Daniel Klevebring, Emma Ivansson, Jingmei Li
Purpose: Interval breast cancer is of clinical interest, as it exhibits an aggressive phenotype and evades detection by screening mammography. A comprehensive picture of somatic changes that drive tumors to become symptomatic in the screening interva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48650183ba5c4bf9fcebbd1a80a0faf
https://doi.org/10.1158/1078-0432.c.6526403.v1
https://doi.org/10.1158/1078-0432.c.6526403.v1
Autor:
Juni Palmgren, Pål R. Njølstad, Hakon Heimer, Eero Vuorio, Eivind Hovig, Preben Bo Mortensen, Hreinn Stefánsson, Kristian Hveem, Nelson B. Freimer, Ole A. Andreassen, Paul W. Franks, Søren Brunak, Aarno Palotie, Camilla Stoltenberg, Gun Peggy Knudsen, Tõnu Esko, Thomas Werge, David M. Hougaard, Mads Melbye, U. Thorsteinsdottir, Joakim Dillner, Wenche Reed, Anu Jalanko, Marc Vaudel, Nathan O. Stitziel, Patrick F. Sullivan, Andres Metspalu, Jaakko Kaprio, Leif Groop, Anders D. Børglum, Kari Stefansson
Publikováno v:
Njølstad, P R, Andreassen, O A, Brunak, S, Børglum, A D, Dillner, J, Esko, T, Franks, P W, Freimer, N, Groop, L, Heimer, H, Hougaard, D M, Hovig, E, Hveem, K, Jalanko, A, Kaprio, J, Knudsen, G P, Melbye, M, Metspalu, A, Mortensen, P B, Palmgren, J, Palotie, A, Reed, W, Stefánsson, H, Stitziel, N O, Sullivan, P F, Thorsteinsdóttir, U, Vaudel, M, Vuorio, E, Werge, T, Stoltenberg, C & Stefánsson, K 2019, ' Roadmap for a precision-medicine initiative in the Nordic region ', Nature Genetics, vol. 51, no. 6, pp. 924-930 . https://doi.org/10.1038/s41588-019-0391-1
The Nordic region, comprising primarily Denmark, Estonia, Finland, Iceland, Norway and Sweden, has many of the necessary characteristics for being at the forefront of genome-based precision medicine. These include egalitarian and universal healthcare
Autor:
Sven Törnberg, Juni Palmgren, Camilla Cristando, Daniel Klevebring, Emma Ivansson, Jan Frisell, Jonas Bergh, Linda S. Lindström, Per Hall, Keith Humphreys, Gabriela Prochazka, Jingmei Li, Johan Hartman, Johan Lindberg, Nicholas P. Tobin, Kamila Czene, Johanna B. Holm, Henrik Grönberg, Mattias Rantalainen
Publikováno v:
Clinical Cancer Research. 23:2584-2592
Purpose: Interval breast cancer is of clinical interest, as it exhibits an aggressive phenotype and evades detection by screening mammography. A comprehensive picture of somatic changes that drive tumors to become symptomatic in the screening interva
Autor:
Tõnu Esko, Ola Spjuth, Huei-Yi Shen, Eco J. C. de Geus, Mats-Ake Persson, Andres Metspalu, Jon Heggland, Leif Groop, Sandra Ose, Isabel Fortier, Johan Rung, Claes Ladenvall, Dorret I. Boomsma, Cornelia M. van Duijn, Samuli Ripatti, Linda Zaharenko, Arnulf Langhammer, Jouke-Jan Hottenga, Annette Peters, Janis Klovins, Christian Gieger, Jennifer R. Harris, Joern Dietrich, Kristian Hveem, Inga Prokopenko, Juni Palmgren, Melanie Waldenberger, Mark I. McCarthy, Jani Heikkinen, Nancy L. Pedersen, Janina S. Ried, Janna Hastings, Jan-Eric Litton, Juha Karvanen, Gonneke Willemsen, Maria Krestyaninova
Publikováno v:
European Journal of Human Genetics
Spjuth, O, Krestyaninova, M, Hastings, J, Shen, H Y, Heikkinen, J, Waldenberger, M, Langhammer, A, Ladenvall, C, Esko, T, Persson, M Å, Heggland, J, Dietrich, J, Ose, S, Gieger, C, Ried, J S, Peters, A, Fortier, I, de Geus, E J C, Klovins, J, Zaharenko, L, Willemsen, G, Hottenga, J J, Litton, J E, Karvanen, J, Boomsma, D I, Groop, L, Rung, J, Palmgren, J, Pedersen, N L, McCarthy, M I, van Duijn, C M, Hveem, K, Metspalu, A, Ripatti, S, Prokopenko, I & Harris, J R 2016, ' Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research ', European Journal of Human Genetics, vol. 24, no. 4, pp. 521-528 . https://doi.org/10.1038/ejhg.2015.165
European Journal of Human Genetics, 24(4), 521-528. Nature Publishing Group
Eur. J. Hum. Genet. 24, 521-528 (2015)
European Journal of Human Genetics; (2015)
Spjuth, O, Krestyaninova, M, Hastings, J, Shen, H Y, Heikkinen, J, Waldenberger, M, Langhammer, A, Ladenvall, C, Esko, T, Persson, M Å, Heggland, J, Dietrich, J, Ose, S, Gieger, C, Ried, J S, Peters, A, Fortier, I, de Geus, E J C, Klovins, J, Zaharenko, L, Willemsen, G, Hottenga, J J, Litton, J E, Karvanen, J, Boomsma, D I, Groop, L, Rung, J, Palmgren, J, Pedersen, N L, McCarthy, M I, van Duijn, C M, Hveem, K, Metspalu, A, Ripatti, S, Prokopenko, I & Harris, J R 2016, ' Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research ', European Journal of Human Genetics, vol. 24, no. 4, pp. 521-528 . https://doi.org/10.1038/ejhg.2015.165
European Journal of Human Genetics, 24(4), 521-528. Nature Publishing Group
Eur. J. Hum. Genet. 24, 521-528 (2015)
European Journal of Human Genetics; (2015)
A wealth of biospecimen samples are stored in modern globally distributed biobanks. Biomedical researchers worldwide need to be able to combine the available resources to improve the power of large-scale studies. A prerequisite for this effort is to