Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Junhui Qi"'
Autor:
Huanhuan Huang, Fanchao Meng, Yanjie Qi, Xiuping Yan, Junhui Qi, Yuanzhen Wu, Yiwei Lin, Xu Chen, Fan He
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background The association of hypertension and depression with mortality has not been fully understood. We aimed to explore the possible independent or joint association of hypertension and depression with mortality. Their interaction effect
Externí odkaz:
https://doaj.org/article/d5f2c7e365e44acc8473f2a49eee8328
Autor:
Zeran Yu, Junhui Qi, Lei Wang, Xiang Yang, Zhengqiao Liu, Xu Chen, Hongling Xu, Yajie Li, Yuyun Chen, Chengguo Dai, Zhen Gu
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundEndoscopic transnasal optic canal decompression is widely used in the treatment of traumatic optic neuropathy (TON) following head and craniofacial trauma. Intraoperative hemorrhage is a catastrophic surgical complication during optic canal
Externí odkaz:
https://doaj.org/article/3c145526e7e04043a3d45432f577b013
Autor:
Huanhuan Huang, Jie Luo, Yanjie Qi, Yuanzhen Wu, Junhui Qi, Xiuping Yan, Gaoyang Xu, Fan He, Yi Zheng
Publikováno v:
Schizophrenia, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract To explore the potential role of circular RNAs (circRNAs) in children developing very early-onset schizophrenia (VEOS). Total RNA was extracted from the plasma samples of 10 VEOS patients and eight healthy controls. Expression profiles of ci
Externí odkaz:
https://doaj.org/article/af9748dea73e4e708be9347d69b65ee5
Publikováno v:
Journal of Affective Disorders. 315:168-173
The association of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and monocyte to lymphocyte ratio (MLR) with depression has been investigated extensively while the results were conflicting. We aim to investigate whether NL
Publikováno v:
Medicinal Chemistry Research. 30:1328-1333
Neurolysin, a member of the metallopeptidase M3 family, plays an important role in many biological processes by regulating bioactive oligopeptides in the central nervous system and periphery. Small molecule modulators of neurolysin have therapeutic p
Publikováno v:
Iranian Journal of Pharmaceutical Research : IJPR
Rho-associated kinases (ROCK) are a class of serine/threonine kinases that play important roles in various biological processes. ROCK are becoming attractive targets for drug designing. A novel scaffold was designed according to molecular hybridizati
Autor:
Fei Zhao, Junhui Qiu, Dongyou Xiang, Pengrui Jiao, Yu Cao, Qingrui Xu, Dairong Qiao, Hui Xu, Yi Cao
Publikováno v:
PeerJ, Vol 12, p e17729 (2024)
Background Global public health is seriously threatened by the escalating issue of antimicrobial resistance (AMR). Antimicrobial peptides (AMPs), pivotal components of the innate immune system, have emerged as a potent solution to AMR due to their th
Externí odkaz:
https://doaj.org/article/9dc6b19685a24b998618c9cf1f845b77
Publikováno v:
Chemical Communications. 56:7621-7624
An amphiphilic dimeric-podophyllotoxin (PODO) phospholipid was synthesized to assemble into liposomes as a combination of prodrug and nanocarrier. The results have demonstrated that the cell membrane-like delivery system possessed an improved cellula
Publikováno v:
Chemical biologydrug designREFERENCES. 98(6)
A series of urea-based ROCK2 inhibitors were design and synthesized. The inhibitory activity on ROCK2 was screened by enzyme-linked immunosorbent assay (ELISA). The study results showed that the urea derivatives exhibited certain ROCK2 inhibitory act
Publikováno v:
Chemical Biology & Drug Design.
Pretubulysin, a biosynthetic precursor of the tubulysins, shows potent biological activity in a variety of tumor cell lines. Although there are several total synthesis routes to tubulysin and pretubulysin reported, the commercialization still has bee