Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Junhua Mai"'
Autor:
Aidan Shen, Aliesha Garrett, Cheng-Chi Chao, Dongliang Liu, Chao Cheng, Zhaohui Wang, Chen Qian, Yangzhi Zhu, Junhua Mai, Chongming Jiang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Tissue-resident memory T cells (TRM) are a specialized subset of long-lived memory T cells that reside in peripheral tissues. However, the impact of TRM-related immunosurveillance on the tumor-immune microenvironment (TIME) and tumor progression acro
Externí odkaz:
https://doaj.org/article/5997ee97a822453ab95d8ce4ff25267d
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1274-1286 (2023)
Lipid-formulated RNA vaccines have been widely used for disease prevention and treatment, yet their mechanism of action and individual components contributing to such actions remain to be delineated. Here, we show that a therapeutic cancer vaccine co
Externí odkaz:
https://doaj.org/article/dcb7dd80bf5a4f62871443eed64df822
Autor:
Ruogu Qi, Shengliang Li, Feng Li, Junhua Mai, Yu Wang, Guixian Zhu, Dechen Zhang, Zheng Li, Haifa Shen, Jianliang Shen, Xuewu Liu
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 10, Pp n/a-n/a (2023)
Scavenging excessively secreted cytokines from plasma is vital for treating cytokine storm syndrome (CSS). Therefore, appropriate adsorbent materials are highly desired for efficient and selectively capturing the plasma cytokines. For this purpose, i
Externí odkaz:
https://doaj.org/article/a3f6b39f293e40de9af77b1889d19ec8
Autor:
Cristian Rodriguez-Aguayo, Emine Bayraktar, Cristina Ivan, Burcu Aslan, Junhua Mai, Guangan He, Lingegowda S. Mangala, Dahai Jiang, Archana S. Nagaraja, Bulent Ozpolat, Arturo Chavez-Reyes, Mauro Ferrari, Rahul Mitra, Zahid H. Siddik, Haifa Shen, Xianbin Yang, Anil K. Sood, Gabriel Lopez-Berestein
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104194- (2022)
Externí odkaz:
https://doaj.org/article/a73feb5a217c497ea1881e81754eb4e1
Autor:
Mei Song, Oladapo O. Yeku, Sarwish Rafiq, Terence Purdon, Xue Dong, Lijing Zhu, Tuo Zhang, Huan Wang, Ziqi Yu, Junhua Mai, Haifa Shen, Briana Nixon, Ming Li, Renier J. Brentjens, Xiaojing Ma
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Ovarian cancer cells often metastasize to the peritoneal cavity, forming spheroid-like structures and promoting a highly immunosuppressive tumor microenvironment. Here, the authors show that the ubiquitin ligase UBR5 is required for ovarian cancer gr
Externí odkaz:
https://doaj.org/article/0a29ad9f32554973937d9a3a66e49066
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 546-556 (2020)
Liposomes, as one of the most successful nanotherapeutics, have a major impact on many biomedical areas. In this study, we performed laser scanning confocal microscope (LSCM) and immunohistochemistry (IHC) assays to investigate the intra-tumor transp
Externí odkaz:
https://doaj.org/article/ecb9d348b535411d861d6cbb94871973
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Myeloid-derived suppressor cells (MDSCs) play a critical role in tumor growth and metastasis. Since they constantly infiltrate into the tumor tissue, these cells are considered as an ideal carrier for tumor-targeted drug delivery. We recently identif
Externí odkaz:
https://doaj.org/article/03a17ce8a2154d8da44237f78bc43cb6
Autor:
Thomas Welte, Junhua Mai, Zhe Zhang, Shaohui Tian, Guodong Zhang, Yitian Xu, Licheng Zhang, Shu-shia Chen, Tian Wang, Haifa Shen
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103349- (2021)
Summary: Myeloid-derived suppressor cells (MDSCs) infiltrate cancer tissue, promote tumor growth, and are associated with resistance to cancer therapies. However, there is no practical approach available to distinguish MDSCs from mature counterparts
Externí odkaz:
https://doaj.org/article/7c73f5260e8348c5902ad6ec129b4de4
Autor:
Junhua Mai, Zhaoqi Li, Xiaojun Xia, Jingxin Zhang, Jun Li, Haoran Liu, Jianliang Shen, Maricela Ramirez, Feng Li, Zheng Li, Kenji Yokoi, Xuewu Liu, Elizabeth A. Mittendorf, Mauro Ferrari, Haifa Shen
Publikováno v:
Advanced Science, Vol 8, Iss 12, Pp n/a-n/a (2021)
Abstract Success in anticancer immune therapy relies on stimulation of tumor antigen‐specific T lymphocytes and effective infiltration of the T cells into tumor tissue. Here, a therapeutic vaccine that promotes proliferation and tumor infiltration
Externí odkaz:
https://doaj.org/article/5d52de9d474d48ab82ccf9b9aec7deb3
Autor:
Cristian Rodriguez-Aguayo, Emine Bayraktar, Cristina Ivan, Burcu Aslan, Junhua Mai, Guangan He, Lingegowda S. Mangala, Dahai Jiang, Archana S. Nagaraja, Bulent Ozpolat, Arturo Chavez-Reyes, Mauro Ferrari, Rahul Mitra, Zahid H. Siddik, Haifa Shen, Xianbin Yang, Anil K. Sood, Gabriel Lopez-Berestein
Publikováno v:
EBioMedicine, Vol 40, Iss , Pp 290-304 (2019)
Background: Inflammatory mediator prostaglandin E2–prostaglandin E2 receptor EP3 (PTGER3) signaling is critical for tumor-associated angiogenesis, tumor growth, and chemoresistance. However, the mechanism underlying these effects in ovarian cancer
Externí odkaz:
https://doaj.org/article/9272908bda63485c88ebd0ea725b30e5