Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Junhong Guan"'
Publikováno v:
Protein & Cell, Vol 9, Iss 4, Pp 365-379 (2017)
ABSTRACT NEDDylation has been shown to participate in the DNA damage pathway, but the substrates of neural precursor cell expressed developmentally downregulated 8 (NEDD8) and the roles of NEDDylation involved in the DNA damage response (DDR) are lar
Externí odkaz:
https://doaj.org/article/0340c18d9be24f2dbb704d74f8550b9d
Publikováno v:
Cancer Biology & Medicine, Vol 6, Iss 3, Pp 192-196 (2009)
OBJECTIVE To investigate the images characteristics of primary malignant intracranial lymphoma . METHODS Retrospective study was conducted on CT/MRI imaging characteristics of 9 cases with primary malignant intracranial lymphoma.RESULTS The patients
Externí odkaz:
https://doaj.org/article/8fef67cb17dc4e14a8fe6db6531532a3
Autor:
Xiangyan Jiang, Yong Ma, Tao Wang, Huinian Zhou, Keshen Wang, Wengui Shi, Long Qin, Junhong Guan, Lianshun Li, Bo Long, Jianli Wang, Xiaoying Guan, Huili Ye, Jing Yang, Zeyuan Yu, Zuoyi Jiao
Publikováno v:
Gastroenterology. 164:1232-1247
Autor:
Xiao Sun, Lu Liu, Chao Wu, Xueying Li, Jinzhen Guo, Junqiu Zhang, Junhong Guan, Nan Wang, Liya Gu, Yang, X. Willian, Guo-Min Li
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/26/2024, Vol. 121 Issue 13, p1-12, 19p
Autor:
Junhong Guan, Guo-Min Li
Publikováno v:
NAR Cancer; Sep2023, Vol. 5 Issue 3, p1-13, 13p
Publikováno v:
Aging (Albany NY)
Intracerebral hemorrhage (ICH) is a common neurological condition that causes severe disability and even death. Even though the mechanism is not clear, increasing evidence shows the efficacy of atorvastatin on treating ICH. In this study, we examined
Publikováno v:
Nucleic acids research. 50(10)
Non-homologous end joining (NHEJ) is the major pathway that mediates the repair of DNA double-strand breaks (DSBs) generated by ionizing radiation (IR). Previously, the DNA helicase RECQL4 was implicated in promoting NHEJ, but its role in the pathway
Autor:
Changzheng Lu, Diego H. Castrillon, Kimberly Batten, Anli Zhang, Yong Liang, Zhenhua Ren, Jian Qiao, Mingming Yang, Tao Wang, Mingyi Chen, Steve Lu, Zhida Liu, Qihuang Jin, Hongyi Zhang, Luis A. Diaz, Bo Li, Chuanhui Han, Xuezhi Cao, Tianshi Lu, Dennis Stephens, Yang Xin Fu, Junhong Guan, Benoit Rousseau, Longchao Liu, Guo Min Li, Jiankun Zhu
Publikováno v:
Cancer Cell
Summary Increased neoantigens in hypermutated cancers with DNA mismatch repair deficiency (dMMR) are proposed as the major contributor to the high objective response rate in anti-PD-1 therapy. However, the mechanism of drug resistance is not fully un
Publikováno v:
Pathology - Research and Practice. 214:1474-1481
Long non-coding RNA urothelial carcinoma associated 1 (lncRNA UCA1) promotes cancer progression and enhances chemoresistance through miR-204-5p in a few cancers. However, no studies have investigated whether UCA1 regulates glioma metastasis through m
Publikováno v:
Journal of Biological Chemistry. 292:8472-8483
Herpes simplex virus 1 (HSV-1) infection manipulates distinct host DNA-damage responses to facilitate virus proliferation, but the molecular mechanisms remain to be elucidated. One possible HSV-1 target might be DNA damage-tolerance mechanisms, such